9F9G
 
 | | Laser excitation effects on BR: Reprocessed Dark from Nogly et al. | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 1-[2,6,10.14-TETRAMETHYL-HEXADECAN-16-YL]-2-[2,10,14-TRIMETHYLHEXADECAN-16-YL]GLYCEROL, Bacteriorhodopsin, ... | | Authors: | Bertrand, Q, Weinert, T, Standfuss, J. | | Deposit date: | 2024-05-07 | | Release date: | 2025-01-22 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Structural effects of high laser power densities on an early bacteriorhodopsin photocycle intermediate.
Nat Commun, 15, 2024
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5O5W
 | | Molybdenum storage protein room-temperature structure determined by serial millisecond crystallography | | Descriptor: | (mu3-oxo)-tris(mu2-oxo)-nonakisoxo-trimolybdenum (VI), ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Steffen, B, Weinert, T, Ermler, U, Standfuss, J. | | Deposit date: | 2017-06-02 | | Release date: | 2017-09-27 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons.
Nat Commun, 8, 2017
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6RO0
 | | CRYSTAL STRUCTURE OF GENETICALLY DETOXIFIED PERTUSSIS TOXIN GDPT. | | Descriptor: | GLYCEROL, Islet-activating protein S2, Islet-activating protein S3, ... | | Authors: | Bertrand, T. | | Deposit date: | 2019-05-10 | | Release date: | 2020-06-03 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.13 Å) | | Cite: | Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity.
Commun Biol, 3, 2020
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8CLB
 | | Colchicine bound to tubulin (T2R-TTL) complex | | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Wranik, M, Kepa, M.W, Bertrand, Q, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CLE
 | | Vinblastine bound to tubulin (T2R-TTL) complex | | Descriptor: | (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wranik, M, Bertrand, Q, Kepa, M.W, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CL7
 | | Krokinobacter eikastus rhodopsin 2 (KR2) in dark state | | Descriptor: | EICOSANE, RETINAL, Sodium pumping rhodopsin | | Authors: | Bertrand, Q, Wranik, M, Kepa, M.W, Weinert, T, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CL8
 | | Krokinobacter eikastus rhodopsin 2 (KR2) extrapolated map 1us after light activation | | Descriptor: | EICOSANE, RETINAL, Sodium pumping rhodopsin | | Authors: | Bertrand, Q, Kepa, M.W, Weinert, T, Wranik, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CL9
 | | Tubulin-DARPin D1 complex | | Descriptor: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Wranik, M, Bertrand, Q, Weinert, T, Kepa, M.W, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CLH
 | | Drug cocktail (Colchicine, Epothilone A, Peloruside, Ansamitocin P3, Vinblastine) bound to tubulin (T2R-TTL) complex | | Descriptor: | (1S,2S,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate, (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, CALCIUM ION, ... | | Authors: | Wranik, M, Bertrand, Q, Kepa, M.W, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CLG
 | | Epothilone A and Colchicine bound to tubulin (T2R-TTL) complex | | Descriptor: | CALCIUM ION, EPOTHILONE A, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wranik, M, Bertrand, Q, Kepa, M.W, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CLD
 | | Ansamitocin P3 bound to tubulin (T2R-TTL) complex | | Descriptor: | (1S,2S,3S,5S,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl 2-methylpropanoate, CALCIUM ION, Detyrosinated tubulin alpha-1B chain, ... | | Authors: | Wranik, M, Kepa, M.W, Bertrand, Q, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CL6
 | | Lysozyme in matrix of hydroxyethylcellulose (HEC) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, LYSOZYME, ... | | Authors: | Bertrand, Q, Kepa, M.W, Weinert, T, Wranik, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.32 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CLF
 | | Z-SolQ2Br bound to tubulin (T2R-TTL) complex | | Descriptor: | 5-[[4-(2-bromoethyl)-3,5-dimethoxy-phenyl]diazenyl]-2-methoxy-phenol, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Wranik, M, Bertrand, Q, Kepa, M, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CL5
 | | Lysozyme in matrix of lipidic cubic phase of monoolein (LCP) | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, LYSOZYME, ... | | Authors: | Bertrand, Q, Kepa, M.W, Weinert, T, Wranik, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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8CLC
 | | Tubulin (T2R-TTL) complex | | Descriptor: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | | Authors: | Wranik, M, Bertrand, Q, Kepa, M.W, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Nat Commun, 14, 2023
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9H20
 | | Continuous dark state structure of Sensory Rhodopsin II solved by serial millisecond crystallography | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2, ... | | Authors: | Ortolani, G, Bosman, R, Branden, G, Neutze, R. | | Deposit date: | 2024-10-10 | | Release date: | 2025-04-30 | | Last modified: | 2025-05-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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8CLA
 | | Z-SBTubA4 photoswitch bound to tubulin-DARPin D1 complex | | Descriptor: | 2-methoxy-5-[2-(5,6,7-trimethoxy-1,3-benzothiazol-2-yl)ethyl]phenol, CALCIUM ION, Designed Ankyrin Repeat Protein (DARPIN) D1, ... | | Authors: | Wranik, M, Bertrand, Q, Kepa, M.W, Weinert, T, Steinmetz, M, Standfuss, J. | | Deposit date: | 2023-02-16 | | Release date: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free electron lasers
To Be Published
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9H1X
 | | Continuously illuminated structure of Sensory Rhodopsin II solved by serial millisecond crystallography | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2 | | Authors: | Ortolani, G, Bosman, R, Branden, G, Neutze, R. | | Deposit date: | 2024-10-10 | | Release date: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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9H1W
 | | Grouped 150-240 ms dark structure of sensory rhodopsin-II solved by serial millisecond crystallography | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2, ... | | Authors: | Ortolani, G, Bosman, R, Branden, G, Neutze, R. | | Deposit date: | 2024-10-10 | | Release date: | 2025-04-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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8PWG
 | | Light structure of sensory rhodopsin-II solved by serial millisecond crystallography 90-120 milliseconds time-bin | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2 | | Authors: | Ortolani, G, Bosman, R, Branden, G, Neutze, R. | | Deposit date: | 2023-07-20 | | Release date: | 2025-02-05 | | Last modified: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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8PWI
 | | Light structure of sensory rhodopsin-II solved by serial millisecond crystallography 60-90 milliseconds time-bin | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2 | | Authors: | Bosman, R, Ortolani, G, Branden, G, Neutze, R. | | Deposit date: | 2023-07-20 | | Release date: | 2025-02-05 | | Last modified: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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8PWQ
 | | Light structure of sensory rhodopsin-II solved by serial millisecond crystallography 120-150 milliseconds time-bin | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2 | | Authors: | Bosman, R, Ortolani, G, Branden, G, Neutze, R. | | Deposit date: | 2023-07-21 | | Release date: | 2025-02-05 | | Last modified: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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8PWJ
 | | Light structure of sensory rhodopsin-II solved by serial millisecond crystallography. 30-60 milliseconds time-bin | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2 | | Authors: | Bosman, R, Ortolani, G, Branden, G, Neutze, R. | | Deposit date: | 2023-07-20 | | Release date: | 2025-02-05 | | Last modified: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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8PWP
 | | Light structure of sensory rhodopsin-II solved by serial millisecond crystallography 0-30 milliseconds time-bin | | Descriptor: | CHLORIDE ION, RETINAL, Sensory rhodopsin-2 | | Authors: | Ortolani, G, Bosman, R, Branden, G, Neutze, R. | | Deposit date: | 2023-07-21 | | Release date: | 2025-02-05 | | Last modified: | 2025-04-23 | | Method: | X-RAY DIFFRACTION (2.08 Å) | | Cite: | Structural basis for the prolonged photocycle of sensory rhodopsin II revealed by serial synchrotron crystallography.
Nat Commun, 16, 2025
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5TUD
 | | Structural Insights into the Extracellular Recognition of the Human Serotonin 2B Receptor by an Antibody | | Descriptor: | 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562 chimera, Anti-5-HT2B Fab heavy chain, Anti-5-HT2B Fab light chain, ... | | Authors: | Ishchenko, A, Wacker, D, Kapoor, M, Zhang, A, Han, G.W, Basu, S, Boutet, S, James, D, Wang, D, Weierstall, U, Liu, W, Katritch, V, Stevens, R.C, Cherezov, V. | | Deposit date: | 2016-11-05 | | Release date: | 2017-07-26 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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