8CLA

Z-SBTubA4 photoswitch bound to tubulin-DARPin D1 complex

Summary for 8CLA

• Entry DOI: 10.2210/pdb8cla/pdb
• Descriptor: Tubulin alpha-1B chain, Tubulin beta-2B chain, Designed Ankyrin Repeat Protein (DARPIN) D1, ... (9 entities in total)
• Functional Keywords: drug-tubulin-complex cell cycle inhibition, cell cycle
• Biological source: synthetic construct; More
• Total number of polymer chains: 3
• Total formula weight: 114510.76

Authors

Wranik, M.,Bertrand, Q.,Kepa, M.W.,Weinert, T.,Steinmetz, M.,Standfuss, J. (deposition date: 2023-02-16, release date: 2024-02-28)

• Primary citation: Wranik, M.,Kepa, M.W.,Beale, E.V.,James, D.,Bertrand, Q.,Weinert, T.,Furrer, A.,Glover, H.,Gashi, D.,Carrillo, M.,Kondo, Y.,Stipp, R.T.,Khusainov, G.,Nass, K.,Ozerov, D.,Cirelli, C.,Johnson, P.J.M.,Dworkowski, F.,Beale, J.H.,Stubbs, S.,Schneider, M.,Krauskopf, K.,Gao, L.,Thorn-Seshold, O.,Bostedt, C.,Bacellar, C.,Steinmetz, M.O.,Milne, C.,Standfuss, J.; A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free electron lasers; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)