7CYG
| Crystal structure of a cysteine-pair mutant (Y113C-P190C) of a bacterial bile acid transporter before disulfide bond formation | Descriptor: | Transporter, sodium/bile acid symporter family | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-09-03 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.198 Å) | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
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7CYK
| Crystal structure of a second cysteine-pair mutant (V110C-I197C) of a bacterial bile acid transporter before disulfide bond formation | Descriptor: | MERCURY (II) ION, Transporter, sodium/bile acid symporter family | Authors: | Wang, X, Lyu, Y, Ji, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-09-03 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.785 Å) | Cite: | An engineered disulfide bridge traps and validates an outward-facing conformation in a bile acid transporter. Acta Crystallogr D Struct Biol, 77, 2021
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7W2B
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7W2H
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7W2C
| The closed conformation of the sigma-1 receptor from Xenopus laevis complexed with PRE084 | Descriptor: | 2-morpholin-4-ylethyl 1-phenylcyclohexane-1-carboxylate, GOLD ION, Sigma non-opioid intracellular receptor 1, ... | Authors: | Meng, F, Sun, Z, Zhou, X. | Deposit date: | 2021-11-23 | Release date: | 2022-03-16 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.335 Å) | Cite: | An open-like conformation of the sigma-1 receptor reveals its ligand entry pathway. Nat Commun, 13, 2022
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7W2E
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7W2G
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7W2D
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7W2F
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7Y5G
| Cryo-EM structure of a eukaryotic ZnT8 in the presence of zinc | Descriptor: | ZINC ION, Zinc transporter 8 | Authors: | Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X. | Deposit date: | 2022-06-17 | Release date: | 2022-12-14 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism. J.Struct.Biol., 215, 2022
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7Y5H
| Cryo-EM structure of a eukaryotic ZnT8 at a low pH | Descriptor: | ZINC ION, Zinc transporter 8 | Authors: | Zhang, S, Fu, C, Luo, Y, Sun, Z, Su, Z, Zhou, X. | Deposit date: | 2022-06-17 | Release date: | 2022-12-14 | Last modified: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.72 Å) | Cite: | Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn 2+ -releasing mechanism. J.Struct.Biol., 215, 2022
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7C72
| Structure of a mycobacterium tuberculosis puromycin-hydrolyzing peptidase | Descriptor: | D-MALATE, GLYCEROL, Prolyl oligopeptidase | Authors: | Ruiz-Carrillo, D, Zhao, Y.H, Feng, Q, Zhou, X, Zhang, Y, Jiang, J, Lukman, M. | Deposit date: | 2020-05-22 | Release date: | 2021-03-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.00004458 Å) | Cite: | Mycobacterium tuberculosis puromycin hydrolase displays a prolyl oligopeptidase fold and an acyl aminopeptidase activity. Proteins, 89, 2021
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7DIX
| Crystal structure of LeuT in lipidic cubic phase at pH 5 | Descriptor: | Na(+):neurotransmitter symporter (Snf family), SELENOMETHIONINE, SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7DJC
| Crystal structure of the G26C/Q250A mutant of LeuT | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-20 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7DJ1
| Crystal structure of the G26C mutant of LeuT | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.528 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7DJ2
| Crystal structure of the G26C/E290S mutant of LeuT | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7DII
| Crystal structure of LeuT in lipidic cubic phase at pH 7 | Descriptor: | LEUCINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION | Authors: | Fan, J, Xiao, Y, Sun, Z, Zhou, X. | Deposit date: | 2020-11-19 | Release date: | 2021-04-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.403 Å) | Cite: | Crystal structures of LeuT reveal conformational dynamics in the outward-facing states. J.Biol.Chem., 296, 2021
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7WXG
| GPR domain closed form of Drosophila P5CS filament with glutamate, ATP, and NADPH | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-03-30 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WXF
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7WXI
| GPR domain of Drosophila P5CS filament with glutamate and ATPgammaS | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-03-30 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WXH
| GPR domain open form of Drosophila P5CS filament with glutamate, ATP, and NADPH | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-03-30 | Last modified: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WX4
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7WX3
| GK domain of Drosophila P5CS filament with glutamate, ATP, and NADPH | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Delta-1-pyrroline-5-carboxylate synthase, GAMMA-GLUTAMYL PHOSPHATE, ... | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2022-02-14 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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7WD4
| Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, NS3 helicase | Authors: | Wang, D.P, Wang, M.Y, Zhou, X, Wang, W.M, Cao, J.M. | Deposit date: | 2021-12-21 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the Ilheus virus helicase: implications for enzyme function and drug design To Be Published
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7F5X
| GK domain of Drosophila P5CS filament with glutamate | Descriptor: | Delta-1-pyrroline-5-carboxylate synthase, GAMMA-L-GLUTAMIC ACID | Authors: | Liu, J.L, Zhong, J, Guo, C.J, Zhou, X. | Deposit date: | 2021-06-23 | Release date: | 2022-04-06 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of dynamic P5CS filaments. Elife, 11, 2022
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