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6DRH
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BU of 6drh by Molmil
ADP-ribosyltransferase toxin/immunity pair
Descriptor: ADP-ribosyl-(Dinitrogen reductase) hydrolase, MAGNESIUM ION, PAAR repeat-containing protein, ...
Authors:Bosch, D.E, Ting, S, Allaire, M, Mougous, J.D.
Deposit date:2018-06-11
Release date:2018-10-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins.
Cell, 175, 2018
6DRE
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BU of 6dre by Molmil
ADP-ribosyltransferase toxin/immunity pair
Descriptor: ADP-ribosyl-(Dinitrogen reductase) hydrolase, MAGNESIUM ION, PAAR repeat-containing protein
Authors:Bosch, D.E, Ting, S, Allaire, M, Mougous, J.D.
Deposit date:2018-06-11
Release date:2018-10-31
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Bifunctional Immunity Proteins Protect Bacteria against FtsZ-Targeting ADP-Ribosylating Toxins.
Cell, 175, 2018
3K81
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BU of 3k81 by Molmil
Structure of the central interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies
Descriptor: MP18 RNA editing complex protein, Single strand antibody VHH domain
Authors:Park, Y.-J, Hol, W.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
8VWP
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BU of 8vwp by Molmil
Langya Virus attachment (G) glycoprotein with K85L/L86K mutation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Langya virus attachment (G) protein
Authors:Gibson, C.G, McCallum, M.M, Veesler, D.V, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-02-02
Release date:2024-05-01
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.21 Å)
Cite:Structure and design of Langya virus glycoprotein antigens.
Proc.Natl.Acad.Sci.USA, 121, 2024
8VQB
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BU of 8vqb by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (3 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQ9
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BU of 8vq9 by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
8VQA
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BU of 8vqa by Molmil
Prefusion stabilized structure of the SARS-CoV-2 fusion machinery
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S2
Authors:Lee, J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2024-01-18
Release date:2024-07-24
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines.
Nat Commun, 15, 2024
7M5E
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BU of 7m5e by Molmil
MERS-CoV S bound to the broadly neutralizing B6 Fab fragment (C3 refinement)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FOLIC ACID, ...
Authors:Sauer, M.M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-03-23
Release date:2021-05-26
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural basis for broad coronavirus neutralization.
Nat.Struct.Mol.Biol., 28, 2021
7U2Q
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BU of 7u2q by Molmil
Influenza Neuraminidase N1-CA09-sNAp-155
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza N1-CA09-sNAp-155
Authors:Acton, O.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-02-24
Release date:2022-04-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure-based design of stabilized recombinant influenza neuraminidase tetramers.
Nat Commun, 13, 2022
7U2T
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BU of 7u2t by Molmil
Influenza Neuraminidase N1-MI15-sNAp-174
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Influenza N1-MI15-sNAp-174
Authors:Acton, O.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-02-24
Release date:2022-04-20
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (3.25 Å)
Cite:Structure-based design of stabilized recombinant influenza neuraminidase tetramers.
Nat Commun, 13, 2022
7U0L
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BU of 7u0l by Molmil
Crystal structure of the CCoV-HuPn-2018 RBD (domain B) in complex with canine APN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-02-18
Release date:2022-08-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
Cell, 185, 2022
7USB
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BU of 7usb by Molmil
CCoV-HuPn-2018 S in the swung out conformation (local refinement of domain 0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-23
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
Cell, 185, 2022
7US9
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BU of 7us9 by Molmil
CCoV-HuPn-2018 S in the proximal conformation (local refinement of domain 0)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-23
Release date:2022-08-24
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
Cell, 185, 2022
7US6
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BU of 7us6 by Molmil
Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the proximal conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-23
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
Cell, 185, 2022
7USA
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BU of 7usa by Molmil
Structure of the human coronavirus CCoV-HuPn-2018 spike glycoprotein with domain 0 in the swung out conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2022-04-23
Release date:2022-08-24
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein.
Cell, 185, 2022
3K80
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BU of 3k80 by Molmil
Structure of essential protein from Trypanosoma brucei
Descriptor: Antibody, MP18 RNA editing complex protein
Authors:Wu, M.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
3K7U
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BU of 3k7u by Molmil
Structure of essential protein from Trypanosoma brucei
Descriptor: Antibody, MP18 RNA editing complex protein
Authors:Wu, M.
Deposit date:2009-10-13
Release date:2010-11-17
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
J.Struct.Biol., 174, 2011
3KZ9
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BU of 3kz9 by Molmil
Crystal structure of the master transcriptional regulator, SmcR, in Vibrio vulnificus provides insight into its DNA recognition mechanism
Descriptor: SULFATE ION, SmcR
Authors:Kim, M.H, Kim, Y, Choi, W.-C, Hwang, J.
Deposit date:2009-12-08
Release date:2010-03-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The crystal structure of SmcR, a quorum-sensing master regulator of Vibrio vulnificus, provides insight into its regulation of transcription
J.Biol.Chem., 285, 2010
2FJP
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BU of 2fjp by Molmil
Human dipeptidyl peptidase IV/CD26 in complex with an inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-(4-{(1S,2S)-2-AMINO-1-[(DIMETHYLAMINO)CARBONYL]-3-[(3S)-3-FLUOROPYRROLIDIN-1-YL]-3-OXOPROPYL}PHENYL)-1H-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-4-IUM, ...
Authors:Scapin, G, Patel, S.B, Becker, J.W.
Deposit date:2006-01-03
Release date:2006-07-04
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.
J.Med.Chem., 49, 2006
5YSO
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BU of 5yso by Molmil
Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434
Descriptor: 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma
Authors:Cho, S.J, Chin, J.W, Yoon, H.S, Jeon, Y.H, Bae, J.H, Song, J.Y.
Deposit date:2017-11-14
Release date:2018-12-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERR gamma ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Clin.Cancer Res., 25, 2019

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數據於2024-11-06公開中

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