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4JMG
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BU of 4jmg by Molmil
Crystal structure of the synthetic protein in complex with pY peptide
Descriptor: Clamp Ptpn11_pY580, MAGNESIUM ION, Tyrosine-protein phosphatase non-receptor type 11
Authors:Yasui, N, Smith, L, Koide, S.
Deposit date:2013-03-14
Release date:2014-04-23
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.403 Å)
Cite:Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.
Mol.Cell, 54, 2014
4JEG
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BU of 4jeg by Molmil
Crystal Structure of Monobody CS1/SHP2 C-SH2 Domain Complex
Descriptor: Monobody CS1, Tyrosine-protein phosphatase non-receptor type 11
Authors:Sha, F, Koide, S.
Deposit date:2013-02-26
Release date:2013-08-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dissection of the BCR-ABL signaling network using highly specific monobody inhibitors to the SHP2 SH2 domains.
Proc.Natl.Acad.Sci.USA, 110, 2013
5E08
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BU of 5e08 by Molmil
Specific Recognition of a Single-stranded RNA Sequence by an Engineered Synthetic Antibody Fragment
Descriptor: Fab Heavy Chain, Fab Light Chain, RNA
Authors:Huang, H, Qin, D, Li, N, Shao, Y, Staley, J.P, Kossiakoff, A.A, Koide, S, Piccirilli, J.A.
Deposit date:2015-09-28
Release date:2016-09-21
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
J.Mol.Biol., 428, 2016
5DC0
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BU of 5dc0 by Molmil
CRYSTAL STRUCTURE OF MONOBODY GG3/ABL1 SH2 DOMAIN COMPLEX
Descriptor: Fibronectin, Tyrosine-protein kinase ABL1
Authors:Wojcik, J.B, Grabe, G, Koide, S.
Deposit date:2015-08-22
Release date:2016-03-02
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Allosteric Inhibition of Bcr-Abl Kinase by High Affinity Monobody Inhibitors Directed to the Src Homology 2 (SH2)-Kinase Interface.
J.Biol.Chem., 291, 2016
5NKQ
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BU of 5nkq by Molmil
Crystal structure of a dual topology fluoride ion channel.
Descriptor: FLUORIDE ION, Monobody, Putative fluoride ion transporter CrcB, ...
Authors:Stockbridge, R, Miller, C, Newstead, S.
Deposit date:2017-03-31
Release date:2017-04-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Crystal structures of a double-barrelled fluoride ion channel.
Nature, 525, 2015
5CWT
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BU of 5cwt by Molmil
Crystal structure of Chaetomium thermophilum Nup57
Descriptor: Nucleoporin NUP57
Authors:Bley, C.J, Hoelz, A.
Deposit date:2015-07-28
Release date:2015-09-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
4JQ5
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BU of 4jq5 by Molmil
Crystal structure of the human Nup49CCS2+3* coiled-coil segment
Descriptor: Nucleoporin p58/p45
Authors:Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
Deposit date:2013-03-20
Release date:2014-09-24
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
4JNU
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BU of 4jnu by Molmil
Crystal structure of the human Nup57CCS3* coiled-coil segment, space group P21
Descriptor: Nucleoporin p54
Authors:Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
Deposit date:2013-03-15
Release date:2014-09-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.445 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
4JNV
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BU of 4jnv by Molmil
Crystal structure of the human Nup57CCS3* coiled-coil segment, space group C2
Descriptor: Nucleoporin p54
Authors:Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
Deposit date:2013-03-15
Release date:2014-09-17
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
5CWS
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BU of 5cws by Molmil
Crystal structure of the intact Chaetomium thermophilum Nsp1-Nup49-Nup57 channel nucleoporin heterotrimer bound to its Nic96 nuclear pore complex attachment site
Descriptor: Nucleoporin NIC96, Nucleoporin NSP1, Nucleoporin NUP49, ...
Authors:Bley, C.J, Petrovic, S, Paduch, M, Lu, V, Kossiakoff, A.A, Hoelz, A.
Deposit date:2015-07-28
Release date:2015-10-14
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.77 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
4JO7
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BU of 4jo7 by Molmil
Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex with 2:2 stoichiometry
Descriptor: Nucleoporin p54, Nucleoporin p58/p45
Authors:Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
Deposit date:2013-03-17
Release date:2014-09-17
Last modified:2016-02-03
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
4JO9
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BU of 4jo9 by Molmil
Crystal structure of the human Nup49CCS2+3* Nup57CCS3* complex 1:2 stoichiometry
Descriptor: Nucleoporin p54, Nucleoporin p58/p45
Authors:Stuwe, T, Bley, C.J, Mayo, D.J, Hoelz, A.
Deposit date:2013-03-18
Release date:2014-09-17
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.499 Å)
Cite:Architecture of the fungal nuclear pore inner ring complex.
Science, 350, 2015
6C83
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BU of 6c83 by Molmil
Structure of Aurora A (122-403) bound to inhibitory Monobody Mb2 and AMPPCP
Descriptor: Aurora kinase A, Mb2 Monobody, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
Authors:Hoemberger, M, Kutter, S, Zorba, A, Nguyen, V, Shohei, A, Shohei, K, Kern, D.
Deposit date:2018-01-24
Release date:2019-02-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Allosteric modulation of a human protein kinase with monobodies.
Proc.Natl.Acad.Sci.USA, 116, 2019
6BF8
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BU of 6bf8 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Descriptor: Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2018-04-04
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Y
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BU of 6b7y by Molmil
Cryo-EM structure of human insulin degrading enzyme
Descriptor: Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-05
Release date:2017-11-08
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF6
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BU of 6bf6 by Molmil
Cryo-EM structure of human insulin degrading enzyme
Descriptor: Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B3Q
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BU of 6b3q by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Descriptor: Insulin, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-09-22
Release date:2017-11-22
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BFC
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BU of 6bfc by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with insulin
Descriptor: Insulin, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2017-12-27
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6B7Z
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BU of 6b7z by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain
Descriptor: FAB H11 heavy chain, FAB H11 light chain, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-05
Release date:2018-01-10
Last modified:2024-10-09
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF9
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BU of 6bf9 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
Descriptor: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2021-04-28
Method:ELECTRON MICROSCOPY (7.2 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6BF7
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BU of 6bf7 by Molmil
Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain
Descriptor: Fab H11-E heavy chain, Fab H11-E light chain, Insulin-degrading enzyme
Authors:Liang, W.G, Zhang, Z, Bailey, L.J, Kossiakoff, A.A, Tan, Y.Z, Wei, H, Carragher, B, Potter, S.C, Tang, W.J.
Deposit date:2017-10-26
Release date:2018-02-07
Last modified:2024-10-23
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme.
Elife, 7, 2018
6UX8
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BU of 6ux8 by Molmil
Structure of monobody 33 MLKL N-terminal domain complex
Descriptor: Mixed lineage kinase domain-like protein, Monobody, ZINC ION
Authors:Birkinshaw, R.W, Petrie, E.J, Murphy, J.M.
Deposit date:2019-11-07
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
6WU1
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BU of 6wu1 by Molmil
Structure of apo LaINDY
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N.C, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WU2
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BU of 6wu2 by Molmil
Structure of the LaINDY-malate complex
Descriptor: DASS family sodium-coupled anion symporter, DECANE, HEXANE, ...
Authors:Sauer, D.B, Marden, J.J, Cocco, N, Song, J.M, Wang, D.N, New York Consortium on Membrane Protein Structure (NYCOMPS)
Deposit date:2020-05-04
Release date:2020-09-16
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
6WK8
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BU of 6wk8 by Molmil
Crystal structure of Gdx-Clo from Small Multidrug Resistance family of transporters in complex with phenylguanidinium
Descriptor: 1-phenylguanidine, DECYL-BETA-D-MALTOPYRANOSIDE, Dodecyldimethylphosphine oxide, ...
Authors:Kermani, A.A, Stockbridge, R.B.
Deposit date:2020-04-15
Release date:2020-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:The structural basis of promiscuity in small multidrug resistance transporters.
Nat Commun, 11, 2020

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數據於2024-10-30公開中

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