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6SO8
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BU of 6so8 by Molmil
BamABCDE in MSP1D1 nanodisc ensemble 1-3
Descriptor: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
Authors:Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P.
Deposit date:2019-08-29
Release date:2021-03-31
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (9.8 Å)
Cite:BamABCDE in MSP1D1 nanodisc ensemble 1-3
To Be Published
6SN4
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BU of 6sn4 by Molmil
BamABCDE in MSP1D1 nanodisc ensemble 0-4
Descriptor: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
Authors:Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P.
Deposit date:2019-08-23
Release date:2021-03-31
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:BamABCDE in MSP1D1 nanodisc ensemble 0-4
To Be Published
6SN7
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BU of 6sn7 by Molmil
BamABCDE in MSP1D1 nanodisc ensemble 0-6
Descriptor: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
Authors:Iadanza, M.G, Ranson, N.A, Radford, S.E, Higgins, A.J, Calabrese, A.N, Schiffrin, B, White, P.
Deposit date:2019-08-23
Release date:2021-03-31
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (8.9 Å)
Cite:BamABCDE in MSP1D1 nanodisc ensemble 0-6
To Be Published
6THD
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BU of 6thd by Molmil
Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E
Descriptor: Genome polyprotein, MYRISTIC ACID, SULFATE ION
Authors:Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G.
Deposit date:2019-11-19
Release date:2020-12-09
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.23 Å)
Cite:Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Plos Pathog., 16, 2020
6THN
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BU of 6thn by Molmil
Multiple Genomic RNA-Coat Protein Contacts Play Vital Roles in the Assembly of Infectious Enterovirus-E symmetry expansion+2fold focused classification
Descriptor: Genome polyprotein, MYRISTIC ACID, RNA Peak 9 Bernoulli Plot, ...
Authors:Chandler-Bostock, R, Mata, C.P, Bingham, R, Dykeman, E.J, Meng, B, Tuthill, T.J, Rowlands, D.J, Ranson, N.A, Twarock, R, Stockley, P.G.
Deposit date:2019-11-20
Release date:2020-12-09
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Assembly of infectious enteroviruses depends on multiple, conserved genomic RNA-coat protein contacts.
Plos Pathog., 16, 2020
6SM3
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BU of 6sm3 by Molmil
Structure of the RagAB peptide importer in the 'closed-closed' state
Descriptor: (1R,4S,6R)-6-({[2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL]OXY}METHYL)-4-HYDROXY-1-{[(15-METHYLHEXADECANOYL)OXY]METHYL}-4-OXIDO-7-OXO-3,5-DIOXA-8-AZA-4-PHOSPHAHEPTACOS-1-YL 15-METHYLHEXADECANOATE, GLY-GLY-ALA-THR-THR-ALA-THR-THR-THR-THR-SER-THR-SER, Lipoprotein RagB, ...
Authors:White, J.B.R, Ranson, N.A, van den Berg, B.
Deposit date:2019-08-21
Release date:2020-05-20
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis.
Nat Microbiol, 5, 2020
6SMQ
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BU of 6smq by Molmil
Structure of the RagAB peptide importer in the 'open-closed' state
Descriptor: (1R,4S,6R)-6-({[2-(ACETYLAMINO)-2-DEOXY-ALPHA-D-GLUCOPYRANOSYL]OXY}METHYL)-4-HYDROXY-1-{[(15-METHYLHEXADECANOYL)OXY]METHYL}-4-OXIDO-7-OXO-3,5-DIOXA-8-AZA-4-PHOSPHAHEPTACOS-1-YL 15-METHYLHEXADECANOATE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Lipoprotein RagB, ...
Authors:White, J.B.R, Ranson, N.A, van den Berg, B.
Deposit date:2019-08-22
Release date:2020-05-20
Last modified:2020-08-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural and functional insights into oligopeptide acquisition by the RagAB transporter from Porphyromonas gingivalis.
Nat Microbiol, 5, 2020
8A41
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BU of 8a41 by Molmil
Nudaurelia capensis omega virus procapsid at pH7.6 (insect cell expressed VLPs)
Descriptor: p70
Authors:Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
Deposit date:2022-06-10
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (4.88 Å)
Cite:Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs)
To be published
7ZQ8
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BU of 7zq8 by Molmil
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=4 VLP)
Descriptor: VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR
Authors:Kingston, N.J, Grehan, K, Snowden, J.S, Alzahrani, J, Ranson, N.A, Rowlands, D.J, Stonehouse, N.J.
Deposit date:2022-04-29
Release date:2023-01-18
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:VelcroVax: a "Bolt-On" Vaccine Platform for Glycoprotein Display.
Msphere, 8, 2023
8A6J
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BU of 8a6j by Molmil
Nudaurelia capensis omega virus maturation intermediate captured at pH6.25 (insect cell expressed VLPs)
Descriptor: p70
Authors:Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
Deposit date:2022-06-17
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Decoding virus maturation with cryo-EM structures of intermediates
To be published
8A3C
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BU of 8a3c by Molmil
Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs)
Descriptor: p70
Authors:Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
Deposit date:2022-06-08
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.92 Å)
Cite:Nudaurelia capensis omega virus maturation intermediate captured at pH5.9 (insect cell expressed VLPs)
To be published
7ZQA
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BU of 7zqa by Molmil
VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR (T=3* VLP)
Descriptor: VelcroVax tandem HBcAg with SUMO-Affimer inserted at MIR
Authors:Kingston, N.J, Grehan, K, Snowden, J.S, Alzahrani, J, Ranson, N.A, Rowlands, D.J, Stonehouse, N.J.
Deposit date:2022-04-29
Release date:2023-01-18
Last modified:2023-08-09
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:VelcroVax: a "Bolt-On" Vaccine Platform for Glycoprotein Display.
Msphere, 8, 2023
8AC6
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BU of 8ac6 by Molmil
Nudaurelia capensis omega virus maturation intermediate captured at pH5.6 (insect cell expressed VLPs): medium class from symmetry expansion
Descriptor: p70
Authors:Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
Deposit date:2022-07-05
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Decoding virus maturation with cryo-EM structures of intermediates
To be published
8ACH
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BU of 8ach by Molmil
Nudaurelia capensis omega virus maturation intermediate captured at pH5.6 (insect cell expressed VLPs): large class from symmetry expansion
Descriptor: p70
Authors:Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
Deposit date:2022-07-05
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.91 Å)
Cite:Decoding virus maturation with cryo-EM structures of intermediates
To be published
8AAY
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BU of 8aay by Molmil
Nudaurelia capensis omega virus maturation intermediate captured at pH5.6 (insect cell expressed VLPs): small class from symmetry expansion
Descriptor: p70
Authors:Castells-Graells, R, Hesketh, E.L, Johnson, J.E, Ranson, N.A, Lawson, D.M, Lomonossoff, G.P.
Deposit date:2022-07-04
Release date:2022-12-28
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Decoding virus maturation with cryo-EM structures of intermediates
To be published
7OJ7
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BU of 7oj7 by Molmil
Crystal structure of human coxsackievirus A24v in complex with a pentavalent N-acetylneuraminic acid conjugate
Descriptor: CALCIUM ION, CHLORIDE ION, Capsid protein VP1, ...
Authors:Zocher, G, Stehle, T.
Deposit date:2021-05-14
Release date:2021-10-13
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Exploring the Effect of Structure-Based Scaffold Hopping on the Inhibition of Coxsackievirus A24v Transduction by Pentavalent N-Acetylneuraminic Acid Conjugates.
Int J Mol Sci, 22, 2021
6RQF
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BU of 6rqf by Molmil
3.6 Angstrom cryo-EM structure of the dimeric cytochrome b6f complex from Spinacia oleracea with natively bound thylakoid lipids and plastoquinone molecules
Descriptor: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, ...
Authors:Malone, L.A, Qian, P, Mayneord, G.E, Hitchcock, A, Farmer, D, Thompson, R, Swainsbury, D.J.K, Ranson, N, Hunter, C.N, Johnson, M.P.
Deposit date:2019-05-15
Release date:2019-11-13
Last modified:2019-12-04
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Cryo-EM structure of the spinach cytochrome b6f complex at 3.6 angstrom resolution.
Nature, 575, 2019
7ZBN
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BU of 7zbn by Molmil
Cryo-EM structure of the human GS-GN complex in the inhibited state
Descriptor: Glycogen [starch] synthase, muscle, Isoform GN-1 of Glycogenin-1
Authors:Marr, L, Zeqiraj, E.
Deposit date:2022-03-23
Release date:2022-06-22
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Mechanism of glycogen synthase inactivation and interaction with glycogenin.
Nat Commun, 13, 2022
8BYL
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BU of 8byl by Molmil
Cryo-EM structure of SKP1-SKP2-CKS1 from the SCFSKP2 E3 ligase complex
Descriptor: Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, S-phase kinase-associated protein 1, ...
Authors:Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.M.
Deposit date:2022-12-13
Release date:2023-06-28
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
8BZO
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BU of 8bzo by Molmil
Cryo-EM structure of CDK2-CyclinA in complex with p27 from the SCFSKP2 E3 ligase Complex
Descriptor: Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B
Authors:Rowland, R.J, Salamina, M, Endicott, J.A, Noble, M.E.
Deposit date:2022-12-15
Release date:2023-06-28
Last modified:2023-07-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of SKP1-SKP2-CKS1 in complex with CDK2-cyclin A-p27KIP1.
Sci Rep, 13, 2023
5JZ7
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BU of 5jz7 by Molmil
NGF IN COMPLEX WITH MEDI578 scFv
Descriptor: Beta-nerve growth factor, MEDI578 scFv, heavy chain, ...
Authors:Olsson, L.-L, Aagaard, A.
Deposit date:2016-05-16
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo.
Sci Rep, 6, 2016
7BM5
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BU of 7bm5 by Molmil
Crystal structure of Fab1, the Fab fragment of the anti-BamA monoclonal antibody MAB1
Descriptor: Fab1 heavy chain, Fab1 light chain
Authors:White, P, Storek, K.M, Rutherford, S.T, Radford, S.E.
Deposit date:2021-01-19
Release date:2021-06-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding.
Nat Commun, 12, 2021
7BNQ
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BU of 7bnq by Molmil
Lateral-closed conformation of the lid-locked BAM complex (BamA E435C S665C, BamBDCE) by cryoEM
Descriptor: Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ...
Authors:Haysom, S.F.
Deposit date:2021-01-22
Release date:2021-06-02
Last modified:2021-07-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:The role of membrane destabilisation and protein dynamics in BAM catalysed OMP folding.
Nat Commun, 12, 2021
7PNQ
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BU of 7pnq by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 43E6 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 43E6 antibody heavy chain, 43E6 antibody light chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022
7PNM
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BU of 7pnm by Molmil
Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 46C12 antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 46C12 antibody heavy chain, ...
Authors:Hurdiss, D.L.
Deposit date:2021-09-07
Release date:2022-04-20
Last modified:2022-11-09
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.
Nat Commun, 13, 2022

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數據於2024-06-12公開中

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