3QZS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qzs by Molmil](/molmil-images/mine/3qzs) | |
3QZV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qzv by Molmil](/molmil-images/mine/3qzv) | Crystal Structure of BPTF PHD-linker-bromo in complex with histone H4K12ac peptide | Descriptor: | Histone H4, Nucleosome-remodeling factor subunit BPTF, ZINC ION | Authors: | Li, H, Ruthenburg, A.J, Patel, D.J. | Deposit date: | 2011-03-07 | Release date: | 2011-06-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.999 Å) | Cite: | Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions. Cell(Cambridge,Mass.), 145, 2011
|
|
3QZT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qzt by Molmil](/molmil-images/mine/3qzt) | Crystal Structure of BPTF bromo in complex with histone H4K16ac - Form II | Descriptor: | GLYCEROL, Histone H4, Nucleosome-remodeling factor subunit BPTF | Authors: | Li, H, Ruthenburg, A.J, Patel, D.J. | Deposit date: | 2011-03-07 | Release date: | 2011-06-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Recognition of a Mononucleosomal Histone Modification Pattern by BPTF via Multivalent Interactions. Cell(Cambridge,Mass.), 145, 2011
|
|
6U9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9k by Molmil](/molmil-images/mine/6u9k) | MLL1 SET N3861I/Q3867L bound to inhibitor 18 (TC-5153) | Descriptor: | 5'-([(3S)-3-amino-3-carboxypropyl]{[1-(3,3-diphenylpropyl)azetidin-3-yl]methyl}amino)-5'-deoxyadenosine, GLYCEROL, Histone-lysine N-methyltransferase, ... | Authors: | Petrunak, E.M, Stuckey, J.A. | Deposit date: | 2019-09-09 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase. Acs Med.Chem.Lett., 11, 2020
|
|
6U9N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9n by Molmil](/molmil-images/mine/6u9n) | MLL1 SET N3861I/Q3867L bound to inhibitor 14 (TC-5139) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl]({1-[(4-chlorophenyl)methyl]azetidin-3-yl}methyl)amino}-5'-deoxyadenosine, Histone-lysine N-methyltransferase, ZINC ION | Authors: | Petrunak, E.M, Stuckey, J.A. | Deposit date: | 2019-09-09 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase. Acs Med.Chem.Lett., 11, 2020
|
|
6U9R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9r by Molmil](/molmil-images/mine/6u9r) | MLL1 SET N3861I/Q3867L bound to inhibitor 12 (TC-5140) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl]({1-[(3-chlorophenyl)methyl]azetidin-3-yl}methyl)amino}-5'-deoxyadenosine, Histone-lysine N-methyltransferase, ZINC ION | Authors: | Petrunak, E.M, Stuckey, J.A. | Deposit date: | 2019-09-09 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase. Acs Med.Chem.Lett., 11, 2020
|
|
6U9M
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6u9m by Molmil](/molmil-images/mine/6u9m) | MLL1 SET N3861I/Q3867L bound to inhibitor 16 (TC-5109) | Descriptor: | 5'-{[(3S)-3-amino-3-carboxypropyl]({1-[(thiophen-2-yl)methyl]azetidin-3-yl}methyl)amino}-5'-deoxyadenosine, GLYCEROL, Histone-lysine N-methyltransferase, ... | Authors: | Petrunak, E.M, Stuckey, J.A. | Deposit date: | 2019-09-09 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Discovery of Potent Small-Molecule Inhibitors of MLL Methyltransferase. Acs Med.Chem.Lett., 11, 2020
|
|
6BYN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6byn by Molmil](/molmil-images/mine/6byn) | Crystal structure of WDR5-Mb(S4) monobody complex | Descriptor: | WD repeat-containing protein 5, WDR5-binding Monobody, Mb(S4) | Authors: | Gupta, A, Koide, S. | Deposit date: | 2017-12-21 | Release date: | 2018-07-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Facile target validation in an animal model with intracellularly expressed monobodies. Nat. Chem. Biol., 14, 2018
|
|
1MOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mod by Molmil](/molmil-images/mine/1mod) | |
1MOA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1moa by Molmil](/molmil-images/mine/1moa) | |
1MOB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mob by Molmil](/molmil-images/mine/1mob) | |
1MOC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1moc by Molmil](/molmil-images/mine/1moc) | |
5XM2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xm2 by Molmil](/molmil-images/mine/5xm2) | Human N-terminal domain of FACT complex subunit SPT16 | Descriptor: | DI(HYDROXYETHYL)ETHER, FACT complex subunit SPT16, GLYCEROL | Authors: | Xu, S, Li, H, Dou, Y, Chen, Y, Jiang, H, Lu, D, Wang, M, Su, D. | Deposit date: | 2017-05-12 | Release date: | 2018-05-16 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.187 Å) | Cite: | The structural basis of human Spt16 N-terminal domain interaction with histone (H3-H4)2tetramer. Biochem.Biophys.Res.Commun., 508, 2019
|
|
7E7Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7y by Molmil](/molmil-images/mine/7e7y) | |
7E88
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e88 by Molmil](/molmil-images/mine/7e88) | |
7E7X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7x by Molmil](/molmil-images/mine/7e7x) | |
7E8C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e8c by Molmil](/molmil-images/mine/7e8c) | SARS-CoV-2 S-6P in complex with 9 Fabs | Descriptor: | 368-2 H, 368-2 L, 604 H, ... | Authors: | Du, S, Xiao, J, Zhang, Z. | Deposit date: | 2021-03-01 | Release date: | 2021-06-09 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
|
|
7E8F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e8f by Molmil](/molmil-images/mine/7e8f) | SARS-CoV-2 NTD in complex with N9 Fab | Descriptor: | 368-2 H, 368-2 L, 604 H, ... | Authors: | Du, S, Xiao, J, Zhang, Z. | Deposit date: | 2021-03-01 | Release date: | 2021-06-09 | Last modified: | 2021-07-14 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines. Cell Res., 31, 2021
|
|
7E86
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e86 by Molmil](/molmil-images/mine/7e86) | |
6J5L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6j5l by Molmil](/molmil-images/mine/6j5l) | |
7P1K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p1k by Molmil](/molmil-images/mine/7p1k) | Cryo EM structure of bison NHA2 in nano disc structure | Descriptor: | CHOLESTEROL HEMISUCCINATE, Phosphatidylinositol, mitochondrial sodium/hydrogen exchanger 9B2 | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | Deposit date: | 2021-07-01 | Release date: | 2022-01-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
|
|
7P1J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p1j by Molmil](/molmil-images/mine/7p1j) | Cryo EM structure of bison NHA2 in detergent structure | Descriptor: | mitochondrial sodium/hydrogen exchanger 9B2 | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | Deposit date: | 2021-07-01 | Release date: | 2022-01-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
|
|
7P1I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7p1i by Molmil](/molmil-images/mine/7p1i) | Cryo EM structure of bison NHA2 in detergent and N-terminal extension helix | Descriptor: | mitochondrial sodium/hydrogen exchanger 9B2 | Authors: | Matsuoka, R, Fudim, R, Jung, S, Drew, D. | Deposit date: | 2021-07-01 | Release date: | 2022-01-26 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Structure, mechanism and lipid-mediated remodeling of the mammalian Na + /H + exchanger NHA2. Nat.Struct.Mol.Biol., 29, 2022
|
|
5JYL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jyl by Molmil](/molmil-images/mine/5jyl) | Human P-cadherin MEC1 with scFv TSP7 bound | Descriptor: | CHLORIDE ION, Cadherin-3, GLYCEROL, ... | Authors: | Caaveiro, J.M.M, Kudo, S, Tsumoto, K. | Deposit date: | 2016-05-14 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Disruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin Sci Rep, 7, 2017
|
|
2ZBG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zbg by Molmil](/molmil-images/mine/2zbg) | Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium | Descriptor: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | Authors: | Toyoshima, C, Ogawa, H, Norimatsu, Y. | Deposit date: | 2007-10-20 | Release date: | 2007-12-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|