7F8Y
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![BU of 7f8y by Molmil](/molmil-images/mine/7f8y) | Crystal structure of the cholecystokinin receptor CCKAR in complex with devazepide | Descriptor: | N-[(3S)-1-methyl-2-oxidanylidene-5-phenyl-3H-1,4-benzodiazepin-3-yl]-1H-indole-2-carboxamide, fusion protein of Cholecystokinin receptor type A and Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8U
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![BU of 7f8u by Molmil](/molmil-images/mine/7f8u) | Crystal structure of the cholecystokinin receptor CCKAR in complex with lintitript | Descriptor: | 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]ethanoic acid, Fusion protein of Cholecystokinin receptor type A and Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8V
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![BU of 7f8v by Molmil](/molmil-images/mine/7f8v) | Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gi | Descriptor: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8W
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![BU of 7f8w by Molmil](/molmil-images/mine/7f8w) | Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq | Descriptor: | Gastrin-17, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-10-13 | Last modified: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7F8X
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![BU of 7f8x by Molmil](/molmil-images/mine/7f8x) | Crystal structure of the cholecystokinin receptor CCKAR in complex with NN9056 | Descriptor: | ASP-SMF-NLE-GLY-TRP-NLE-OEM-MEA-NH2 (NN9056), Cholecystokinin receptor type A,Endolysin | Authors: | Zhang, X, He, C, Wang, M, Zhou, Q, Yang, D, Zhu, Y, Wu, B, Zhao, Q. | Deposit date: | 2021-07-02 | Release date: | 2021-12-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of the human cholecystokinin receptors bound to agonists and antagonists. Nat.Chem.Biol., 17, 2021
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7XNA
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![BU of 7xna by Molmil](/molmil-images/mine/7xna) | Crystal structure of somatostatin receptor 2 (SSTR2) with peptide antagonist CYN 154806 | Descriptor: | CYN 154806, Somatostatin receptor type 2,Endo-1,4-beta-xylanase | Authors: | Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-28 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XMS
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![BU of 7xms by Molmil](/molmil-images/mine/7xms) | CryoEM structure of somatostatin receptor 4 (SSTR4) in complex with Gi1 and its endogeneous ligand SST-14 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-26 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XMR
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![BU of 7xmr by Molmil](/molmil-images/mine/7xmr) | CryoEM structure of the somatostatin receptor 2 (SSTR2) in complex with Gi1 and its endogeneous peptide ligand SST-14 | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-26 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XN9
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![BU of 7xn9 by Molmil](/molmil-images/mine/7xn9) | Crystal structure of SSTR2 and L-054,522 complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Somatostatin receptor type 2,Endo-1,4-beta-xylanase, tert-butyl (2S)-6-azanyl-2-[[(2R,3S)-3-(1H-indol-3-yl)-2-[[4-(2-oxidanylidene-3H-benzimidazol-1-yl)piperidin-1-yl]carbonylamino]butanoyl]amino]hexanoate | Authors: | Zhao, W, Han, S, Qiu, N, Feng, W, Lu, M, Yang, D, Wang, M.-W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-28 | Release date: | 2022-08-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7XMT
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![BU of 7xmt by Molmil](/molmil-images/mine/7xmt) | CryoEM structure of somatostatin receptor 4 (SSTR4) with Gi1 and J-2156 | Descriptor: | (2~{S})-2-[[(2~{S})-4-azanyl-2-[(4-methylnaphthalen-1-yl)sulfonylamino]butanoyl]amino]-3-phenyl-propanimidic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wenli, Z, Shuo, H, Na, Q, Wenbo, Z, Mengjie, L, Dehua, Y, Ming-Wei, W, Wu, B, Zhao, Q. | Deposit date: | 2022-04-26 | Release date: | 2022-08-03 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural insights into ligand recognition and selectivity of somatostatin receptors. Cell Res., 32, 2022
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7NB0
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![BU of 7nb0 by Molmil](/molmil-images/mine/7nb0) | Structure of the DNA-binding domain of SEPALLATA 3 | Descriptor: | Developmental protein SEPALLATA 3 | Authors: | Zubieta, C, Nanao, M.H. | Deposit date: | 2021-01-25 | Release date: | 2021-07-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The intervening domain is required for DNA-binding and functional identity of plant MADS transcription factors. Nat Commun, 12, 2021
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7S7Q
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![BU of 7s7q by Molmil](/molmil-images/mine/7s7q) | |
7S7R
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![BU of 7s7r by Molmil](/molmil-images/mine/7s7r) | Plasmodium falciparum protein Pf12 bound to nanobody G7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Merozoite surface protein P12, Nanobody G7, ... | Authors: | Dietrich, M.H, Tham, W.H. | Deposit date: | 2021-09-17 | Release date: | 2022-03-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structure of the Pf12 and Pf41 heterodimeric complex of Plasmodium falciparum 6-cysteine proteins. FEMS Microbes, 3, 2022
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9BJK
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![BU of 9bjk by Molmil](/molmil-images/mine/9bjk) | Inactive mu opioid receptor bound to Nb6, naloxone and NAM | Descriptor: | Mu-type opioid receptor, Naloxone, Nalpha-[({(1M)-1-[5-(benzyloxy)pyridin-3-yl]naphthalen-2-yl}sulfanyl)acetyl]-3-methoxy-N,4-dimethyl-L-phenylalaninamide, ... | Authors: | O'Brien, E.S, Wang, H, Kaavya Krishna, K, Zhang, C, Kobilka, B.K. | Deposit date: | 2024-04-25 | Release date: | 2024-07-17 | Last modified: | 2024-08-14 | Method: | ELECTRON MICROSCOPY (3.26 Å) | Cite: | A mu-opioid receptor modulator that works cooperatively with naloxone. Nature, 631, 2024
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7MZG
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![BU of 7mzg by Molmil](/molmil-images/mine/7mzg) | SARS-CoV-2 receptor binding domain bound to Fab PDI 42 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, PDI 42 heavy chain, ... | Authors: | Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZK
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![BU of 7mzk by Molmil](/molmil-images/mine/7mzk) | SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 96 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, ... | Authors: | Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZJ
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![BU of 7mzj by Molmil](/molmil-images/mine/7mzj) | SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 93 | Descriptor: | GLYCEROL, PDI 93 heavy chain, PDI 93 light chain, ... | Authors: | Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZH
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![BU of 7mzh by Molmil](/molmil-images/mine/7mzh) | SARS-CoV-2 receptor binding domain bound to Fab WCSL 119 | Descriptor: | Spike protein S1, WCSL 119 heavy chain, WCSL 119 light chain, ... | Authors: | Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZI
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![BU of 7mzi by Molmil](/molmil-images/mine/7mzi) | SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 | Descriptor: | GLYCEROL, Spike protein S1, TETRAETHYLENE GLYCOL, ... | Authors: | Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZL
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![BU of 7mzl by Molmil](/molmil-images/mine/7mzl) | SARS-CoV-2 receptor binding domain bound to Fab PDI 210 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 210 heavy chain, PDI 210 light chain, ... | Authors: | Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZN
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![BU of 7mzn by Molmil](/molmil-images/mine/7mzn) | SARS-CoV-2 receptor binding domain bound to Fab PDI 231 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 231 heavy chain, PDI 231 light chain, ... | Authors: | Pymm, P, Tan, L.L, Dietrich, M.H, Chan, L.J, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZF
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![BU of 7mzf by Molmil](/molmil-images/mine/7mzf) | SARS-CoV-2 receptor binding domain bound to Fab PDI 37 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ... | Authors: | Pymm, P, Chan, L.J, Dietrich, M.H, Tan, L.L, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.493 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7MZM
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![BU of 7mzm by Molmil](/molmil-images/mine/7mzm) | SARS-CoV-2 receptor binding domain bound to Fab PDI 215 | Descriptor: | ISOPROPYL ALCOHOL, PDI 215 heavy chain, PDI 215 light chain, ... | Authors: | Pymm, P, Dietrich, M.H, Tan, L.L, Chan, L.J, Tham, W.H. | Deposit date: | 2021-05-24 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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7RR0
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![BU of 7rr0 by Molmil](/molmil-images/mine/7rr0) | SARS-CoV-2 receptor binding domain bound to Fab PDI 222 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 222 Fab Heavy Chain, PDI 222 Fab Light Chain, ... | Authors: | Pymm, P, Glukhova, A, Black, K.A, Tham, W.H. | Deposit date: | 2021-08-08 | Release date: | 2021-10-06 | Last modified: | 2021-10-27 | Method: | ELECTRON MICROSCOPY (3.12 Å) | Cite: | Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
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3CUT
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![BU of 3cut by Molmil](/molmil-images/mine/3cut) | Crystal structure of glycogen phosphorylase b in complex with N-(-D-glucopyranosyl)-N'-(2-naphthyl)oxamide | Descriptor: | Glycogen phosphorylase, muscle form, N-[(naphthalen-2-ylamino)(oxo)acetyl]-beta-D-glucopyranosylamine | Authors: | Kyritsi, C, Chrysina, E.D, Leonidas, D.D, Zographos, S.E, Oikonomakos, N.G. | Deposit date: | 2008-04-17 | Release date: | 2009-04-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Tracking structure activity relationships of glycogen phosphorylase inhibitors: synthesis, kinetic and crystallographic evaluation of analogues of N-(-D-glucopyranosyl)-N'-oxamides To be Published
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