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1GY6
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BU of 1gy6 by Molmil
NTF2 from rat, ammonium sulphate conditions
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Bayliss, R, Stewart, M.
Deposit date:2002-04-21
Release date:2002-06-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural Basis for the Interaction between Ntf2 and Nucleoporin Fxfg Repeats
Embo J., 21, 2002
8FZK
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BU of 8fzk by Molmil
Dimeric human importin alpha subunit
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Importin subunit alpha-1, MAGNESIUM ION
Authors:Donnelly, C.M, Stewart, M, Forwood, J.K.
Deposit date:2023-01-29
Release date:2023-02-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Dimeric human importin alpha subunit
To Be Published
8FWL
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BU of 8fwl by Molmil
Crystal structure of Australian bat lyssavirus nucleoprotein in complex with phosphoprotein chaperone
Descriptor: DI(HYDROXYETHYL)ETHER, Phosphoprotein,Nucleoprotein
Authors:Donnelly, C.M, Stewart, M, Forwood, J.K.
Deposit date:2023-01-23
Release date:2023-03-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Structural Determination of the Australian Bat Lyssavirus Nucleoprotein and Phosphoprotein Complex.
Viruses, 16, 2023
8G4J
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BU of 8g4j by Molmil
Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state
Descriptor: Importin subunit alpha
Authors:Hawker, J.E, Roby, J.A, Stewart, M, Forwood, J.K.
Deposit date:2023-02-09
Release date:2023-02-22
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in cargo-free state
To Be Published
8GAI
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BU of 8gai by Molmil
Cavia porcellus (guinea pig) importin-alpha 1 in complex with Bimax2 peptide
Descriptor: Bimax2, Importin subunit alpha
Authors:Hawker, J.E, Forwood, J.K, Donnelly, C.M, Stewart, M.
Deposit date:2023-02-22
Release date:2023-04-05
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Cavia porcellus (guinea pig) importin-alpha 1 in complex with bimax2 peptide
To Be Published
8G8R
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BU of 8g8r by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Importin subunit alpha-1, Transcription factor RelB
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:monopartite p52 NLS in complex with Importin alpha 2
To Be Published
8G8S
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BU of 8g8s by Molmil
bipartite p52 NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, Nuclear factor NF-kappa-B p100 subunit isoform X1
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:p52 bipartite NLS in complex with Importin alpha 2
To Be Published
8G8Q
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BU of 8g8q by Molmil
RelB NLS in complex with Importin alpha 2
Descriptor: Importin subunit alpha-1, bacterial peptide, monopartite p52 NLS
Authors:Tsimbslyuk, S, Stewart, M, Forwood, J.K.
Deposit date:2023-02-19
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:p52 monopartite NLS in complex with Importin alpha 2
To Be Published
2BJQ
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BU of 2bjq by Molmil
Crystal structure of the nematode sperm cell motility protein MFP2
Descriptor: MFP2A
Authors:Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M.
Deposit date:2005-02-07
Release date:2005-03-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility
J.Mol.Biol., 347, 2005
2C1T
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BU of 2c1t by Molmil
Structure of the Kap60p:Nup2 complex
Descriptor: IMPORTIN ALPHA SUBUNIT, NUCLEOPORIN NUP2
Authors:Matsuura, Y, Stewart, M.
Deposit date:2005-09-20
Release date:2005-11-22
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Nup50/Npap60 Function in Nuclear Import Complex Disassembly and Importin Recycling
Embo J., 24, 2005
2BJR
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BU of 2bjr by Molmil
Crystal structure of the nematode sperm cell motility protein MFP2B
Descriptor: MFP2B, SULFATE ION, ZINC ION
Authors:Grant, R.P, Buttery, S.M, Ekman, G.C, Roberts, T.M, Stewart, M.
Deposit date:2005-02-07
Release date:2005-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of Mfp2 and its Function in Enhancing Msp Polymerization in Ascaris Sperm Amoeboid Motility
J.Mol.Biol., 347, 2005
4CYI
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BU of 4cyi by Molmil
Chaetomium thermophilum Pan3
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
4CYK
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BU of 4cyk by Molmil
Structural basis for binding of Pan3 to Pan2 and its function in mRNA recruitment and deadenylation
Descriptor: PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3, ZINC ION
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-05-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation.
Embo J., 33, 2014
4CYJ
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BU of 4cyj by Molmil
Chaetomium thermophilum Pan2:Pan3 complex
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN, ...
Authors:Wolf, J, Valkov, E, Allen, M.D, Meineke, B, Gordiyenko, Y, McLaughlin, S.H, Olsen, T.M, Robinson, C.V, Bycroft, M, Stewart, M, Passmore, L.A.
Deposit date:2014-04-11
Release date:2014-06-11
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation
Embo J., 33, 2014
1O6O
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BU of 1o6o by Molmil
Importin Beta aa1-442 bound to five FxFG repeats from yeast Nsp1p. Second crystal form
Descriptor: IMPORTIN BETA-1 SUBUNIT, NUCLEOPORIN NSP1
Authors:Bayliss, R, Stewart, M.
Deposit date:2002-10-10
Release date:2003-10-17
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
J.Biol.Chem., 277, 2002
1O6P
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BU of 1o6p by Molmil
Importin Beta bound to a GLFG Nucleoporin peptide
Descriptor: IMPORTIN BETA-1 SUBUNIT, SYNTHETIC GLFG PEPTIDE
Authors:Bayliss, R, Stewart, M.
Deposit date:2002-10-10
Release date:2003-04-24
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Glfg and Fxfg Nucleoporins Bind to Overlapping Sites on Importin-Beta
J.Biol.Chem., 277, 2002
1QG4
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BU of 1qg4 by Molmil
CANINE GDP-RAN F72Y MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
1OAI
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BU of 1oai by Molmil
Complex between Tap UBA domain and FxFG nucleoporin peptide
Descriptor: FXFG NUCLEOPORIN PEPTIDE, NUCLEAR RNA EXPORT FACTOR
Authors:Grant, R.P, Neuhaus, D, Stewart, M.
Deposit date:2003-01-14
Release date:2003-02-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1 Å)
Cite:Structural Basis for the Interaction between the Tap/Nxf1 Uba Domain and Fg Nucleoporins at 1 A Resolution
J.Mol.Biol., 326, 2003
1QG2
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BU of 1qg2 by Molmil
CANINE GDP-RAN R76E MUTANT
Descriptor: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PROTEIN (RAN)
Authors:Kent, H.M, Moore, M.S, Quimby, B.B, Baker, A.M.E, McCoy, A.J, Murphy, G.A, Corbett, A.H, Stewart, M.
Deposit date:1999-04-20
Release date:1999-06-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Engineered mutants in the switch II loop of Ran define the contribution made by key residues to the interaction with nuclear transport factor 2 (NTF2) and the role of this interaction in nuclear protein import.
J.Mol.Biol., 289, 1999
3EA5
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BU of 3ea5 by Molmil
Kap95p Binding Induces the Switch Loops of RanGDP to adopt the GTP-bound Conformation: Implications for Nuclear Import Complex Assembly Dynamics
Descriptor: GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, Importin subunit beta-1, ...
Authors:Forwood, J.K, Lonhienne, J.K, Guncar, G, Stewart, M, Marfori, M, Kobe, B.
Deposit date:2008-08-24
Release date:2008-10-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Kap95p binding induces the switch loops of RanGDP to adopt the GTP-bound conformation: implications for nuclear import complex assembly dynamics.
J.Mol.Biol., 383, 2008
3MK8
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BU of 3mk8 by Molmil
The MCL-1 BH3 Helix is an Exclusive MCL-1 Inhibitor and Apoptosis Sensitizer
Descriptor: Induced myeloid leukemia cell differentiation protein Mcl-1
Authors:Stewart, M, Fire, E, Keating, A.E, Walensky, L.D.
Deposit date:2010-04-14
Release date:2010-06-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.321 Å)
Cite:The MCL-1 BH3 helix is an exclusive MCL-1 inhibitor and apoptosis sensitizer.
Nat.Chem.Biol., 6, 2010
1AR0
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BU of 1ar0 by Molmil
NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J, Stewart, M.J.
Deposit date:1997-08-08
Release date:1997-12-24
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1ASK
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BU of 1ask by Molmil
NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT
Descriptor: NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J, Stewart, M.J.
Deposit date:1997-08-11
Release date:1998-01-28
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
6OMB
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BU of 6omb by Molmil
Cdc48 Hexamer (Subunits A to E) with substrate bound to the central pore
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ...
Authors:Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S.
Deposit date:2019-04-18
Release date:2019-07-17
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the Cdc48 segregase in the act of unfolding an authentic substrate.
Science, 365, 2019
6OPC
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BU of 6opc by Molmil
Cdc48 Hexamer in a complex with substrate and Shp1(Ubx Domain)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Cell division control protein 48, ...
Authors:Cooney, I, Han, H, Stewart, M, Carson, R.H, Hansen, D, Price, J.C, Hill, C.P, Shen, P.S.
Deposit date:2019-04-24
Release date:2019-07-10
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structure of the Cdc48 segregase in the act of unfolding an authentic substrate.
Science, 365, 2019

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數據於2024-10-16公開中

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