8HMC
 
 | | base module state 1 of Tetrahymena IFT-A | | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transport protein 43 homolog, Tetratricopeptide repeat protein, ... | | Authors: | Ma, Y, Wu, J, Lei, M. | | Deposit date: | 2022-12-03 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
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8HME
 | | head module state 1 of Tetrahymena IFT-A | | Descriptor: | Intraflagellar transport protein 122 homolog, Intraflagellar transporter, WD40 repeat protein, ... | | Authors: | Ma, Y, Wu, J, Lei, M. | | Deposit date: | 2022-12-03 | | Release date: | 2023-06-14 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural insight into the intraflagellar transport complex IFT-A and its assembly in the anterograde IFT train.
Nat Commun, 14, 2023
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3DBQ
 | | Crystal structure of TTK kinase domain | | Descriptor: | Dual specificity protein kinase TTK | | Authors: | Wang, W, Yang, Y.T, Gao, Y.F, Zhu, S.C, Wang, F, Old, W, Xu, Q.B, Resing, K, Ahn, N, Lei, M, Liu, X.D. | | Deposit date: | 2008-06-02 | | Release date: | 2009-02-10 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and Mechanistic Insights into Mps1 Kinase Activation
J.CELL.MOL.MED., 13, 2008
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6AH3
 | | Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate | | Descriptor: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, ... | | Authors: | Lan, P, Tan, M, Wu, J, Lei, M. | | Deposit date: | 2018-08-16 | | Release date: | 2018-10-17 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.48 Å) | | Cite: | Structural insight into precursor tRNA processing by yeast ribonuclease P.
Science, 362, 2018
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5XXE
 | | Crystal structure of Poz1 and Tpz1 | | Descriptor: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, SULFATE ION, ... | | Authors: | Xue, J, Chen, H, Wu, J, Lei, M. | | Deposit date: | 2017-07-03 | | Release date: | 2017-12-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.
Cell Res., 27, 2017
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5XXF
 | | Crystal structure of Poz1, Tpz1 and Rap1 | | Descriptor: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, Rap1, ... | | Authors: | Xue, J, Chen, H, Wu, J, Lei, M. | | Deposit date: | 2017-07-03 | | Release date: | 2017-12-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex.
Cell Res., 27, 2017
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4O26
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8J0N
 | | cryo-EM structure of human EMC | | Descriptor: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | | Authors: | Li, M, Zhang, C, Wu, J, Lei, M. | | Deposit date: | 2023-04-11 | | Release date: | 2024-04-03 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.47 Å) | | Cite: | Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024
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8J0O
 | | cryo-EM structure of human EMC and VDAC | | Descriptor: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | | Authors: | Li, M, Zhang, C, Wu, J, Lei, M. | | Deposit date: | 2023-04-11 | | Release date: | 2024-04-03 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024
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3K6G
 | | Crystal structure of Rap1 and TRF2 complex | | Descriptor: | Telomeric repeat-binding factor 2, Telomeric repeat-binding factor 2-interacting protein 1 | | Authors: | Chen, Y, Rai, R, Yang, Y.T, Zheng, H, Chang, S, Lei, M. | | Deposit date: | 2009-10-08 | | Release date: | 2010-10-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms.
Nat.Struct.Mol.Biol., 18, 2011
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3RMH
 | | Crystal Structure of yeast telomere protein Cdc13 OB4 | | Descriptor: | Yeast Cdc13 OB4 | | Authors: | Sun, J, Yang, Y, Lei, M. | | Deposit date: | 2011-04-20 | | Release date: | 2011-11-09 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.902 Å) | | Cite: | Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70.
Mol.Cell.Biol., 32, 2012
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3KF6
 | | Crystal structure of S. pombe Stn1-ten1 complex | | Descriptor: | Protein stn1, Protein ten1 | | Authors: | Sun, J, Yu, E.Y, Yang, Y.T, Confer, L.A, Sun, S.H, Wan, K, Lue, N.F, Lei, M. | | Deposit date: | 2009-10-27 | | Release date: | 2009-12-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Stn1-Ten1 is an Rpa2-Rpa3-like complex at telomeres.
Genes Dev., 23, 2009
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3RSN
 | | Crystal Structure of the N-terminal region of Human Ash2L | | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | | Authors: | Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M. | | Deposit date: | 2011-05-02 | | Release date: | 2011-06-22 | | Last modified: | 2011-12-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
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3U85
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3U86
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5XUP
 | | Crystal structure of TRF1 and TERB1 | | Descriptor: | Telomere repeats-binding bouquet formation protein 1, Telomeric repeat-binding factor 1 | | Authors: | Long, J, Huang, C, Wu, J, Lei, M. | | Deposit date: | 2017-06-24 | | Release date: | 2017-11-01 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Telomeric TERB1-TRF1 interaction is crucial for male meiosis.
Nat. Struct. Mol. Biol., 24, 2017
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5Y59
 | | Crystal structure of Ku80 and Sir4 | | Descriptor: | ATP-dependent DNA helicase II subunit 2, SULFATE ION, Sir4p | | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | | Deposit date: | 2017-08-08 | | Release date: | 2017-12-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.402 Å) | | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
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5Y5A
 | | Crystal structure of Est1 and Cdc13 | | Descriptor: | KLLA0F20702p, KLLA0F20922p | | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | | Deposit date: | 2017-08-08 | | Release date: | 2017-12-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.206 Å) | | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
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5Y58
 | | Crystal structure of Ku70/80 and TLC1 | | Descriptor: | ATP-dependent DNA helicase II subunit 1, ATP-dependent DNA helicase II subunit 2, TLC1 | | Authors: | Chen, H, Xue, J, Wu, J, Lei, M. | | Deposit date: | 2017-08-08 | | Release date: | 2017-12-20 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Insights into Yeast Telomerase Recruitment to Telomeres
Cell, 172, 2018
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7C7A
 | | Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1 | | Descriptor: | Internal Transcribed Spacer 1, MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, ... | | Authors: | Lan, P, Wu, J, Lei, M. | | Deposit date: | 2020-05-24 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
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7C79
 | | Cryo-EM structure of yeast Ribonuclease MRP | | Descriptor: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease MRP RNA subunit NME1, ... | | Authors: | Lan, P, Wu, J, Lei, M. | | Deposit date: | 2020-05-24 | | Release date: | 2020-07-08 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
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6K0B
 | | cryo-EM structure of archaeal Ribonuclease P with mature tRNA | | Descriptor: | 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ... | | Authors: | Wan, F, Lan, P, Wu, J, Lei, M. | | Deposit date: | 2019-05-05 | | Release date: | 2019-06-19 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
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7D58
 | | cryo-EM structure of human RNA polymerase III in elongating state | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | | Deposit date: | 2020-09-25 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
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7D59
 | | cryo-EM structure of human RNA polymerase III in apo state | | Descriptor: | DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... | | Authors: | Wang, Q, Wan, F, Lan, P, Wu, J, Lei, M. | | Deposit date: | 2020-09-25 | | Release date: | 2021-02-17 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Structural insights into transcriptional regulation of human RNA polymerase III.
Nat.Struct.Mol.Biol., 28, 2021
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6K0A
 | | cryo-EM structure of an archaeal Ribonuclease P | | Descriptor: | 50S ribosomal protein L7Ae, RPR, Ribonuclease P protein component 1, ... | | Authors: | Wan, F, Lan, P, Wu, J, Lei, M. | | Deposit date: | 2019-05-05 | | Release date: | 2019-06-19 | | Last modified: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme.
Nat Commun, 10, 2019
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