1PJG
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![BU of 1pjg by Molmil](/molmil-images/mine/1pjg) | RNA/DNA Hybrid Decamer of CAAAGAAAAG/CTTTTCTTTG | Descriptor: | 5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3', 5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3', CALCIUM ION | Authors: | Kopka, M.L, Lavelle, L, Han, G.W, Ng, H.-L, Dickerson, R.E. | Deposit date: | 2003-06-02 | Release date: | 2003-12-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.15 Å) | Cite: | An unusual sugar conformation in the structure of an RNA/DNA decamer of the polypurine tract may affect recognition by RNase H. J.Mol.Biol., 334, 2003
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1I6Z
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![BU of 1i6z by Molmil](/molmil-images/mine/1i6z) | BAG DOMAIN OF BAG1 COCHAPERONE | Descriptor: | BAG-FAMILY MOLECULAR CHAPERONE REGULATOR-1 | Authors: | Briknarova, K, Takayama, S, Brive, L, Havert, M.L, Knee, D.A, Velasco, J, Homma, S, Cabezas, E, Stuart, J, Hoyt, D.W, Satterthwait, A.C, Llinas, M, Reed, J.C, Ely, K.R. | Deposit date: | 2001-03-06 | Release date: | 2001-09-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural analysis of BAG1 cochaperone and its interactions with Hsc70 heat shock protein. Nat.Struct.Biol., 8, 2001
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1PJI
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![BU of 1pji by Molmil](/molmil-images/mine/1pji) | Crystal structure of wild type Lactococcus lactis FPG complexed to a 1,3 propanediol containing DNA | Descriptor: | DNA (5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*A)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Pereira, K, Serre, L, Zelwer, C, Castaing, B. | Deposit date: | 2003-06-03 | Release date: | 2004-08-03 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into abasic site for Fpg specific binding and catalysis: comparative high-resolution crystallographic studies of Fpg bound to various models of abasic site analogues-containing DNA. Nucleic Acids Res., 33, 2005
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1PJ4
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![BU of 1pj4 by Molmil](/molmil-images/mine/1pj4) | Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, ATP, Mn++, and allosteric activator fumarate. | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, D-MALATE, FUMARIC ACID, ... | Authors: | Tao, X, Yang, Z, Tong, L. | Deposit date: | 2003-05-31 | Release date: | 2003-09-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure, 11, 2003
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5UFX
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![BU of 5ufx by Molmil](/molmil-images/mine/5ufx) | Estrogen Receptor Alpha Ligand Binding Domain in Complex with OP1074 | Descriptor: | (2S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-{2-[(3R)-3-methylpyrrolidin-1-yl]ethoxy}phenyl)-2H-1-benzopyran-7-ol, Estrogen receptor | Authors: | Fanning, S.W, Hodges-Gallagher, L, Myles, D.C, Sun, R, Fowler, C.E, Green, B.D, Harmon, C.L, Greene, G.L, Kushner, P.J. | Deposit date: | 2017-01-06 | Release date: | 2018-01-10 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.5503 Å) | Cite: | Specific stereochemistry of OP-1074 disrupts estrogen receptor alpha helix 12 and confers pure antiestrogenic activity. Nat Commun, 9, 2018
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1IB8
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![BU of 1ib8 by Molmil](/molmil-images/mine/1ib8) | SOLUTION STRUCTURE AND FUNCTION OF A CONSERVED PROTEIN SP14.3 ENCODED BY AN ESSENTIAL STREPTOCOCCUS PNEUMONIAE GENE | Descriptor: | CONSERVED PROTEIN SP14.3 | Authors: | Yu, L, Gunasekera, A.H, Mack, J, Olejniczak, E.T, Chovan, L.E, Ruan, X, Towne, D.L, Lerner, C.G, Fesik, S.W. | Deposit date: | 2001-03-27 | Release date: | 2002-03-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | SOLUTION STRUCTURE AND FUNCTION OF A CONSERVED PROTEIN SP14.3 ENCODED BY AN ESSENTIAL STREPTOCOCCUS PNEUMONIAE GENE J.Mol.Biol., 311, 2001
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5TV7
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![BU of 5tv7 by Molmil](/molmil-images/mine/5tv7) | 2.05 Angstrom Resolution Crystal Structure of Peptidoglycan-Binding Protein from Clostridioides difficile in Complex with Glutamine Hydroxamate. | Descriptor: | GLUTAMINE HYDROXAMATE, Putative peptidoglycan-binding/hydrolysing protein | Authors: | Minasov, G, Wawrzak, Z, Shuvalova, L, Winsor, J, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-11-08 | Release date: | 2016-12-14 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | 2.05 Angstrom Resolution Crystal Structure of Peptidoglycan-Binding Protein from Clostridioides difficile in Complex with Glutamine Hydroxamate. To Be Published
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1I70
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![BU of 1i70 by Molmil](/molmil-images/mine/1i70) | CRYSTAL STRUCTURE OF RNASE SA Y86F MUTANT | Descriptor: | GUANYL-SPECIFIC RIBONUCLEASE SA, SULFATE ION | Authors: | Sevcik, J, Urbanikova, L. | Deposit date: | 2001-03-07 | Release date: | 2001-09-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Tyrosine hydrogen bonds make a large contribution to protein stability. J.Mol.Biol., 312, 2001
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1PJO
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![BU of 1pjo by Molmil](/molmil-images/mine/1pjo) | Crystal Structure of an RNA/DNA hybrid of HIV-1 PPT | Descriptor: | 5'-D(*CP*TP*TP*TP*TP*CP*TP*TP*TP*G)-3', 5'-R(*CP*AP*AP*AP*GP*AP*AP*AP*AP*G)-3', MAGNESIUM ION | Authors: | Kopka, M.L, Lavelle, L, Han, G.W, Ng, H.-L, Dickerson, R.E. | Deposit date: | 2003-06-03 | Release date: | 2003-12-09 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | An Unusual Sugar Conformation in the Structure of an RNA/DNA
Decamer of the Polypurine Tract May Affect Recognition by RNase H J.Mol.Biol., 334, 2003
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4NG8
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![BU of 4ng8 by Molmil](/molmil-images/mine/4ng8) | Dialyzed HEW lysozyme batch crystallized in 1.9 M CsCl and collected at 100 K. | Descriptor: | CESIUM ION, CHLORIDE ION, Lysozyme C | Authors: | Benas, P, Legrand, L, Ries-Kautt, M. | Deposit date: | 2013-11-01 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Weak protein-cationic co-ion interactions addressed by X-ray crystallography and mass spectrometry. Acta Crystallogr.,Sect.D, 70, 2014
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1PJ2
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![BU of 1pj2 by Molmil](/molmil-images/mine/1pj2) | Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor NADH, Mn++, and allosteric activator fumarate | Descriptor: | (2S)-2-hydroxybutanedioic acid, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FUMARIC ACID, ... | Authors: | Tao, X, Yang, Z, Tong, L. | Deposit date: | 2003-05-30 | Release date: | 2003-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure, 11, 2003
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1PJ1
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![BU of 1pj1 by Molmil](/molmil-images/mine/1pj1) | RIBONUCLEOTIDE REDUCTASE R2-D84E/W48F SOAKED WITH FERROUS IONS AT PH 5 | Descriptor: | FE (III) ION, MERCURY (II) ION, Ribonucleoside-diphosphate reductase 1 beta chain | Authors: | Voegtli, W.C, Sommerhalter, M, Saleh, L, Baldwin, J, Bollinger Jr, J.M, Rosenzweig, A.C. | Deposit date: | 2003-05-30 | Release date: | 2004-01-13 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Variable coordination geometries at the diiron(II) active site of ribonucleotide reductase R2. J.Am.Chem.Soc., 125, 2003
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1PM9
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![BU of 1pm9 by Molmil](/molmil-images/mine/1pm9) | CRYSTAL STRUCTURE OF HUMAN MNSOD H30N, Y166F MUTANT | Descriptor: | MANGANESE (III) ION, Superoxide dismutase [Mn], mitochondrial | Authors: | Fan, L, Tainer, J.A. | Deposit date: | 2003-06-10 | Release date: | 2003-12-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Amino acid substitution at the dimeric interface of human manganese superoxide dismutase J.Biol.Chem., 279, 2004
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1PJF
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![BU of 1pjf by Molmil](/molmil-images/mine/1pjf) | Solid State NMR structure of the Pf1 Major Coat Protein in Magnetically Aligned Bacteriophage | Descriptor: | COAT PROTEIN B | Authors: | Thiriot, D.S, Nevzorov, A.A, Zagyanskiy, L, Wu, C.H, Opella, S.J. | Deposit date: | 2003-06-02 | Release date: | 2004-08-10 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | Structure of the coat protein in Pf1 bacteriophage determined by solid-state NMR spectroscopy. J.Mol.Biol., 341, 2004
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5U47
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![BU of 5u47 by Molmil](/molmil-images/mine/5u47) | 1.95 Angstrom Resolution Crystal Structure of Penicillin Binding Protein 2X from Streptococcus thermophilus | Descriptor: | ACETATE ION, CHLORIDE ION, Penicillin binding protein 2X | Authors: | Minasov, G, Shuvalova, L, Cardona-Correa, A, Dubrovska, I, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2016-12-03 | Release date: | 2016-12-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | 1.95 Angstrom Resolution Crystal Structure of Penicillin Binding Protein 2X from Streptococcus thermophilus. To Be Published
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7QEN
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![BU of 7qen by Molmil](/molmil-images/mine/7qen) | S.c. Condensin core in DNA- and ATP-bound state | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Condensin complex subunit 1, Condensin complex subunit 2, ... | Authors: | Lecomte, L, Hassler, M, Haering, C, Eustermann, S. | Deposit date: | 2021-12-03 | Release date: | 2022-06-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | A hold-and-feed mechanism drives directional DNA loop extrusion by condensin. Science, 376, 2022
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7QQK
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![BU of 7qqk by Molmil](/molmil-images/mine/7qqk) | TIR-SAVED effector bound to cA3 | Descriptor: | RNA (5'-R(P*AP*AP*A)-3'), TIR_SAVED fusion protein | Authors: | Spagnolo, L, White, M.F, Hogrel, G, Guild, A. | Deposit date: | 2022-01-09 | Release date: | 2022-06-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cyclic nucleotide-induced helical structure activates a TIR immune effector. Nature, 608, 2022
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1PKZ
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![BU of 1pkz by Molmil](/molmil-images/mine/1pkz) | Crystal structure of human glutathione transferase (GST) A1-1 | Descriptor: | 2-HYDROXYETHYL DISULFIDE, Glutathione S-transferase A1 | Authors: | Grahn, E, Jakobsson, E, Gustafsson, A, Grehn, L, Olin, B, Wahlberg, M, Madsen, D, Kleywegt, G.J, Mannervik, B. | Deposit date: | 2003-06-06 | Release date: | 2004-06-22 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix. Acta Crystallogr.,Sect.D, 62, 2006
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7QFW
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![BU of 7qfw by Molmil](/molmil-images/mine/7qfw) | S.c. Condensin peripheral Ycg1 subcomplex bound to DNA | Descriptor: | Condensin complex subunit 2, Condensin complex subunit 3, Synthetic DNA ligand, ... | Authors: | Lecomte, L, Hassler, M, Haering, C, Eustermann, S. | Deposit date: | 2021-12-06 | Release date: | 2022-06-15 | Last modified: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.86 Å) | Cite: | A hold-and-feed mechanism drives directional DNA loop extrusion by condensin. Science, 376, 2022
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1HIY
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![BU of 1hiy by Molmil](/molmil-images/mine/1hiy) | Binding of nucleotides to NDP kinase | Descriptor: | 3'-DEOXY 3'-AMINO ADENOSINE-5'-DIPHOSPHATE, NUCLEOSIDE DIPHOSPHATE KINASE | Authors: | Cervoni, L, Lascu, I, Xu, Y, Gonin, P, Morr, M, Merouani, M, Janin, J, Giartoso, A. | Deposit date: | 2001-01-05 | Release date: | 2001-05-31 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Binding of Nucleotides to Nucleoside Diphosphate Kinase: A Calorimetric Study. Biochemistry, 40, 2001
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1PQW
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![BU of 1pqw by Molmil](/molmil-images/mine/1pqw) | |
5UG4
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![BU of 5ug4 by Molmil](/molmil-images/mine/5ug4) | Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, ACETATE ION, CALCIUM ION, ... | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2017-01-06 | Release date: | 2017-01-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structure of spermidine N-acetyltransferase SpeG from Vibrio cholerae To Be Published
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1PJ3
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![BU of 1pj3 by Molmil](/molmil-images/mine/1pj3) | Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate pyruvate, cofactor NAD+, Mn++, and allosteric activator fumarate. | Descriptor: | FUMARIC ACID, MANGANESE (II) ION, NAD-dependent malic enzyme, ... | Authors: | Tao, X, Yang, Z, Tong, L. | Deposit date: | 2003-05-30 | Release date: | 2003-11-11 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of substrate complexes of malic enzyme and insights into the catalytic mechanism. Structure, 11, 2003
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5UHS
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![BU of 5uhs by Molmil](/molmil-images/mine/5uhs) | Structure of a SemiSWEET D57A mutant | Descriptor: | MONOVACCENIN, Sugar transporter SemiSWEET, beta-D-glucopyranose | Authors: | Fastman, N.M, Feng, L. | Deposit date: | 2017-01-11 | Release date: | 2017-08-02 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism of Substrate Translocation in an Alternating Access Transporter. Cell, 169, 2017
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1PL4
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![BU of 1pl4 by Molmil](/molmil-images/mine/1pl4) | Crystal Structure of human MnSOD Y166F mutant | Descriptor: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | Authors: | Fan, L, Tainer, J.A. | Deposit date: | 2003-06-06 | Release date: | 2003-12-16 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Amino acid substitution at the dimeric interface of human manganese superoxide dismutase J.Biol.Chem., 279, 2004
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