1ILR
 
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6JKY
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7BXO
 | | Crystal structure of the toxin-antitoxin with AMP-PNP | | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Toxin-antitoxin system antidote Mnt family, ... | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-04-20 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
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7C5Z
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6JUD
 | | Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant | | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6JU6
 | | Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant | | Descriptor: | NITRATE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6JUC
 | | Aspergillus oryzae pro-tyrosinase oxygen-bound C92A/H103F mutant | | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.44 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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7CNB
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6JU5
 | | Aspergillus oryzae pro-tyrosinase C92A/F513Y mutant | | Descriptor: | COPPER (II) ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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7CAJ
 | | Crystal structure of SETDB1 Tudor domain in complexed with Compound 2. | | Descriptor: | 3-methyl-2-[[(3R,5R)-1-methyl-5-phenyl-piperidin-3-yl]amino]-5H-pyrrolo[3,2-d]pyrimidin-4-one, Histone-lysine N-methyltransferase SETDB1 | | Authors: | Guo, Y.P, Liang, X, Xin, M, Luyi, H, Chengyong, W, Yang, S.Y. | | Deposit date: | 2020-06-08 | | Release date: | 2021-04-07 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.198 Å) | | Cite: | Structure-Guided Discovery of a Potent and Selective Cell-Active Inhibitor of SETDB1 Tudor Domain.
Angew.Chem.Int.Ed.Engl., 60, 2021
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6JU8
 | | Aspergillus oryzae active-tyrosinase copper-bound C92A mutant | | Descriptor: | COPPER (II) ION, NITRATE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.27 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6JUB
 | | Radiation damage in Aspergillus oryzae pro-tyrosinase oxygen-bound C92A mutant | | Descriptor: | COPPER (II) ION, PEROXIDE ION, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.54 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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7D2L
 | | Crystal structure of the Cas12i1 R-loop complex before target DNA cleavage | | Descriptor: | 12i1-D647A, CITRIC ACID, DNA (26-MER), ... | | Authors: | Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. | | Deposit date: | 2020-09-16 | | Release date: | 2021-05-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
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7D8C
 | | Crystal structure of the Cas12i1-crRNA binary complex | | Descriptor: | 12i1, CITRIC ACID, RNA (3-MER), ... | | Authors: | Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. | | Deposit date: | 2020-10-07 | | Release date: | 2021-05-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
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7D3J
 | | Crystal structure of the Cas12i1 R-loop complex after target DNA cleavage | | Descriptor: | 12i1-WT, CITRIC ACID, DNA (23-MER), ... | | Authors: | Zhang, B, Luo, D.Y, Li, Y, OuYang, S.Y. | | Deposit date: | 2020-09-19 | | Release date: | 2021-05-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1.
Nat Commun, 12, 2021
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6KS5
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6L00
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6ATH
 | | Cdk2/cyclin A/p27-KID-deltaC | | Descriptor: | Cyclin-A2, Cyclin-dependent kinase 2, Cyclin-dependent kinase inhibitor 1B, ... | | Authors: | White, S.W, Yun, M. | | Deposit date: | 2017-08-29 | | Release date: | 2018-09-12 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | Dynamic anticipation by Cdk2/Cyclin A-bound p27 mediates signal integration in cell cycle regulation.
Nat Commun, 10, 2019
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6M6U
 | | Crystal structure the toxin-antitoxin MntA-HpeT mutant-D39ED41E | | Descriptor: | Toxin-antitoxin system antitoxin MntA family, Toxin-antitoxin system toxin HepN family | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-03-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.349 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
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6M6W
 | | Crystal structure the toxin-antitoxin MntA-HpeT mutant-Y104A | | Descriptor: | Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-03-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.611 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
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6M6V
 | | Crystal structure the toxin-antitoxin MntA-HepT | | Descriptor: | RNA (5'-R(P*AP*AP*A)-3'), Toxin-antitoxin system antidote Mnt family, Toxin-antitoxin system toxin HepN family | | Authors: | Ouyang, S.Y, Zhen, X.K. | | Deposit date: | 2020-03-16 | | Release date: | 2020-09-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (3.08 Å) | | Cite: | Novel polyadenylylation-dependent neutralization mechanism of the HEPN/MNT toxin/antitoxin system.
Nucleic Acids Res., 48, 2020
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6JU9
 | | Aspergillus oryzae active-tyrosinase copper-bound C92A mutant complexed with L-tyrosine | | Descriptor: | 3,4-DIHYDROXYPHENYLALANINE, COPPER (II) ION, NITRATE ION, ... | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6K4L
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6JU7
 | | Aspergillus oryzae active-tyrosinase copper-depleted C92A mutant complexed with L-tyrosine | | Descriptor: | NITRATE ION, TYROSINE, Tyrosinase | | Authors: | Fujieda, N, Umakoshi, K, Nishikawa, Y, Kurisu, G, Itoh, S. | | Deposit date: | 2019-04-13 | | Release date: | 2020-05-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | Copper-Oxygen Dynamics in the Tyrosinase Mechanism.
Angew.Chem.Int.Ed.Engl., 59, 2020
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6K4R
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