4RZA
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![BU of 4rza by Molmil](/molmil-images/mine/4rza) | Pre-mRNA-splicing factor 38A AS 1-205 | Descriptor: | Pre-mRNA-splicing factor 38A | Authors: | Schuetze, T, Ulrich, A, Wahl, M.C. | Deposit date: | 2014-12-19 | Release date: | 2015-12-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The N-terminal domain of the unusual SR protein hPrp38 is an interaction hub in the spliceosome To be Published
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5K8Y
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![BU of 5k8y by Molmil](/molmil-images/mine/5k8y) | Structure of the Mus musclus Langerin carbohydrate recognition domain | Descriptor: | C-type lectin domain family 4 member K, CALCIUM ION, GLYCEROL, ... | Authors: | Loll, B, Aretz, J, Rademacher, C, Wahl, M.C. | Deposit date: | 2016-05-31 | Release date: | 2016-12-07 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent. J. Biol. Chem., 292, 2017
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6Q9M
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![BU of 6q9m by Molmil](/molmil-images/mine/6q9m) | Central Fibronectin-III array of RIM-binding protein | Descriptor: | PHOSPHATE ION, RIM-binding protein, isoform F | Authors: | Driller, J.D, Habibi, S, Wahl, M.C, Loll, B. | Deposit date: | 2018-12-18 | Release date: | 2020-01-15 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.453 Å) | Cite: | RIM-binding protein couples synaptic vesicle recruitment to release sites. J.Cell Biol., 219, 2020
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5LWO
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![BU of 5lwo by Molmil](/molmil-images/mine/5lwo) | Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at 100K | Descriptor: | 2-HYDROXYETHYL DISULFIDE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Loll, B, Consentius, P, Gohlke, U, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | Deposit date: | 2016-09-18 | Release date: | 2017-03-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.183 Å) | Cite: | Internal Dynamics of the 3-Pyrroline-N-Oxide Ring in Spin-Labeled Proteins. J Phys Chem Lett, 8, 2017
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5LM7
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![BU of 5lm7 by Molmil](/molmil-images/mine/5lm7) | Crystal structure of the lambda N-Nus factor complex | Descriptor: | 30S ribosomal protein S10, Antitermination protein N, N utilization substance protein B homolog, ... | Authors: | Said, N, Santos, K, Weber, G, Wahl, M.C. | Deposit date: | 2016-07-29 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural basis for lambda N-dependent processive transcription antitermination. Nat Microbiol, 2, 2017
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5LM9
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![BU of 5lm9 by Molmil](/molmil-images/mine/5lm9) | Structure of E. coli NusA | Descriptor: | MAGNESIUM ION, SULFATE ION, Transcription termination/antitermination protein NusA | Authors: | Said, N, Weber, G, Santos, K, Wahl, M.C. | Deposit date: | 2016-07-29 | Release date: | 2017-04-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.143 Å) | Cite: | Structural basis for lambda N-dependent processive transcription antitermination. Nat Microbiol, 2, 2017
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6QWS
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![BU of 6qws by Molmil](/molmil-images/mine/6qws) | |
6QV3
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![BU of 6qv3 by Molmil](/molmil-images/mine/6qv3) | Crystal structure of the Ski2 RNA-helicase Brr2 from Chaetomium thermophilum bound to ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, ... | Authors: | Absmeier, E, Santos, K.F, Wahl, M.C. | Deposit date: | 2019-03-01 | Release date: | 2020-01-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular Mechanism Underlying Inhibition of Intrinsic ATPase Activity in a Ski2-like RNA Helicase. Structure, 28, 2020
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4YHU
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![BU of 4yhu by Molmil](/molmil-images/mine/4yhu) | Yeast Prp3 C-terminal fragment 296-469 | Descriptor: | U4/U6 small nuclear ribonucleoprotein PRP3, YTTRIUM (III) ION | Authors: | Liu, S, Wahl, M.C. | Deposit date: | 2015-02-27 | Release date: | 2015-07-22 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A composite double-/single-stranded RNA-binding region in protein Prp3 supports tri-snRNP stability and splicing. Elife, 4, 2015
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8ALZ
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![BU of 8alz by Molmil](/molmil-images/mine/8alz) | Cryo-EM structure of ASCC3 in complex with ASC1 | Descriptor: | Activating signal cointegrator 1, Activating signal cointegrator 1 complex subunit 3, ZINC ION | Authors: | Jia, J, Hilal, T, Loll, B, Wahl, M.C. | Deposit date: | 2022-08-01 | Release date: | 2023-03-08 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Cryo-EM structure of ASCC3 in complex with ASC1 Nat Commun, 2023
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8BCC
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![BU of 8bcc by Molmil](/molmil-images/mine/8bcc) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 39 | Descriptor: | 1,2-ETHANEDIOL, 3-oxidanylbenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCG
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![BU of 8bcg by Molmil](/molmil-images/mine/8bcg) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 86 | Descriptor: | 1,2-ETHANEDIOL, 4-chloranyl-~{N}-methoxy-~{N}-methyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCH
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![BU of 8bch by Molmil](/molmil-images/mine/8bch) | Human Brr2 Helicase Region in complex with Sulfaguanidine | Descriptor: | 1-(4-aminophenyl)sulfonylguanidine, U5 small nuclear ribonucleoprotein 200 kDa helicase | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BC9
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![BU of 8bc9 by Molmil](/molmil-images/mine/8bc9) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 24 | Descriptor: | 1,2-ETHANEDIOL, N-hydroxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BC8
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![BU of 8bc8 by Molmil](/molmil-images/mine/8bc8) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 18 | Descriptor: | 1,2-ETHANEDIOL, 3-azanyl-4-oxidanyl-benzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCE
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![BU of 8bce by Molmil](/molmil-images/mine/8bce) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 76 | Descriptor: | 1,2-ETHANEDIOL, N-methoxybenzenesulfonamide, Pre-mRNA-processing-splicing factor 8, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCA
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![BU of 8bca by Molmil](/molmil-images/mine/8bca) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 26 | Descriptor: | 1,2-ETHANEDIOL, 3-azanyl-~{N}-methyl-4-(methylamino)benzenesulfonamide, GLYCEROL, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCF
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![BU of 8bcf by Molmil](/molmil-images/mine/8bcf) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 78 | Descriptor: | 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.42 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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8BCD
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![BU of 8bcd by Molmil](/molmil-images/mine/8bcd) | |
8BCB
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![BU of 8bcb by Molmil](/molmil-images/mine/8bcb) | Human Brr2 Helicase Region in complex with C-tail deleted Jab1 and compound 34 | Descriptor: | 1,2-ETHANEDIOL, Pre-mRNA-processing-splicing factor 8, SULFANILAMIDE, ... | Authors: | Vester, K, Loll, B, Wahl, M.C. | Deposit date: | 2022-10-15 | Release date: | 2023-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Conformation-dependent ligand hot spots in the spliceosomal RNA helicase BRR2. Acta Crystallogr D Struct Biol, 79, 2023
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5M62
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![BU of 5m62 by Molmil](/molmil-images/mine/5m62) | Structure of the Mus musclus Langerin carbohydrate recognition domain in complex with glucose | Descriptor: | C-type lectin domain family 4 member K, CALCIUM ION, GLYCEROL, ... | Authors: | Loll, B, Aretz, J, Rademacher, C, Wahl, M.C. | Deposit date: | 2016-10-24 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Bacterial Polysaccharide Specificity of the Pattern Recognition Receptor Langerin Is Highly Species-dependent. J. Biol. Chem., 292, 2017
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5M52
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![BU of 5m52 by Molmil](/molmil-images/mine/5m52) | Crystal structure of yeast Brr2 full-lenght in complex with Prp8 Jab1 domain | Descriptor: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 | Authors: | Wollenhaupt, J, Absmeier, E, Becke, C, Santos, K.F, Wahl, M.C. | Deposit date: | 2016-10-20 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
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5NX0
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![BU of 5nx0 by Molmil](/molmil-images/mine/5nx0) | Structure of Spin-labelled T4 lysozyme mutant L115C-R119C-R1 at room temperature | Descriptor: | Endolysin | Authors: | Gohlke, U, Loll, B, Consentius, P, Mueller, R, Kaupp, M, Heinemann, U, Wahl, M.C, Risse, T. | Deposit date: | 2017-05-09 | Release date: | 2017-07-19 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.803 Å) | Cite: | Combining EPR spectroscopy and X-ray crystallography to elucidate the structure and dynamics of conformationally constrained spin labels in T4 lysozyme single crystals. Phys Chem Chem Phys, 19, 2017
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5M59
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![BU of 5m59 by Molmil](/molmil-images/mine/5m59) | Crystal structure of Chaetomium thermophilum Brr2 helicase core in complex with Prp8 Jab1 domain | Descriptor: | ACETATE ION, Pre-mRNA splicing helicase-like protein, Putative pre-mRNA splicing factor | Authors: | Absmeier, E, Becke, C, Wollenhaupt, J, Santos, K.F, Wahl, M.C. | Deposit date: | 2016-10-20 | Release date: | 2016-12-21 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
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5M5P
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![BU of 5m5p by Molmil](/molmil-images/mine/5m5p) | S. cerevisiae spliceosomal helicase Brr2 (271-end) in complex with the Jab/MPN domain of S. cerevisiae Prp8 | Descriptor: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 | Authors: | Becke, C, Absmeier, E, Wollenhaupt, J, Santos, K.F, Wahl, M.C. | Deposit date: | 2016-10-22 | Release date: | 2016-12-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2. Cell Cycle, 16, 2017
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