7QD7
| TarM(Se)_G117R | Descriptor: | CHLORIDE ION, GLYCEROL, PENTAETHYLENE GLYCOL, ... | Authors: | Guo, Y, Stehle, T. | Deposit date: | 2021-11-26 | Release date: | 2023-05-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition. Sci Adv, 9, 2023
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7QNT
| TarM(Se) native | Descriptor: | 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | Authors: | Guo, Y, Stehle, T. | Deposit date: | 2021-12-22 | Release date: | 2023-05-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition. Sci Adv, 9, 2023
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7QH9
| TarM(Se)_G117R-4RboP | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, TarM(Se)_G117R-4RboP, ... | Authors: | Guo, Y, Stehle, T. | Deposit date: | 2021-12-10 | Release date: | 2023-05-10 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.689 Å) | Cite: | Invasive Staphylococcus epidermidis uses a unique processive wall teichoic acid glycosyltransferase to evade immune recognition. Sci Adv, 9, 2023
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7PA6
| JC polyomavirus VP1 in complex with scFv 27C11 | Descriptor: | Major capsid protein VP1, scFv 27C11 antibody heavy chain | Authors: | Harprecht, C, Stroeh, L.J, Nagel, F, Freytag, J, Stehle, T. | Deposit date: | 2021-07-29 | Release date: | 2023-02-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural characterization of human neutralizing antibodies against JC and BK polyomavirus To Be Published
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7PA9
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7PA8
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3INB
| Structure of the measles virus hemagglutinin bound to the CD46 receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin glycoprotein, Membrane cofactor protein, ... | Authors: | Santiago, C, Celma, M.L, Stehle, T, Casasnovas, J.M. | Deposit date: | 2009-08-12 | Release date: | 2009-12-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the measles virus hemagglutinin bound to the CD46 receptor Nat.Struct.Mol.Biol., 17, 2010
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3I4Z
| Crystal structure of the dimethylallyl tryptophan synthase FgaPT2 from Aspergillus fumigatus | Descriptor: | 1,3-BUTANEDIOL, GLYCEROL, Tryptophan dimethylallyltransferase | Authors: | Schall, C, Zocher, G, Stehle, T. | Deposit date: | 2009-07-03 | Release date: | 2009-09-01 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria Proc.Natl.Acad.Sci.USA, 106, 2009
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3I4X
| Crystal structure of the dimethylallyl tryptophan synthase FgaPT2 from Aspergillus fumigatus in complex with Trp and DMSPP | Descriptor: | DIMETHYLALLYL S-THIOLODIPHOSPHATE, GLYCEROL, TRYPTOPHAN, ... | Authors: | Schall, C, Zocher, G, Stehle, T. | Deposit date: | 2009-07-03 | Release date: | 2009-09-01 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria Proc.Natl.Acad.Sci.USA, 106, 2009
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4U62
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4U5Z
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4U61
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4U60
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4WDY
| JC Polyomavirus VP1 five-fold pore mutant N221Q | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Major capsid protein VP1 | Authors: | Stroh, L.J, Stehle, T. | Deposit date: | 2014-09-09 | Release date: | 2015-02-18 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Modulation of a Pore in the Capsid of JC Polyomavirus Reduces Infectivity and Prevents Exposure of the Minor Capsid Proteins. J.Virol., 89, 2015
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3EOY
| Structure of Reovirus sigma1 in Complex with Its Receptor Junctional Adhesion Molecule-A | Descriptor: | Junctional adhesion molecule A, Outer capsid protein sigma-1 | Authors: | Kirchner, E, Guglielmi, K.M, Dermody, T.S, Stehle, T. | Deposit date: | 2008-09-29 | Release date: | 2008-11-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structure of reovirus sigma1 in complex with its receptor junctional adhesion molecule-A Plos Pathog., 4, 2008
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4Y7T
| Structural analysis of MurU | Descriptor: | GLYCEROL, Nucleotidyl transferase, SULFATE ION | Authors: | Renner-Schneck, M.G, Stehle, T. | Deposit date: | 2015-02-16 | Release date: | 2015-03-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the N-Acetylmuramic Acid alpha-1-Phosphate (MurNAc-alpha 1-P) Uridylyltransferase MurU, a Minimal Sugar Nucleotidyltransferase and Potential Drug Target Enzyme in Gram-negative Pathogens. J.Biol.Chem., 290, 2015
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4Y7U
| Structural analysis of MurU | Descriptor: | 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, GLYCEROL, ... | Authors: | Renner-Schneck, M.G, Stehle, T. | Deposit date: | 2015-02-16 | Release date: | 2015-03-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the N-Acetylmuramic Acid alpha-1-Phosphate (MurNAc-alpha 1-P) Uridylyltransferase MurU, a Minimal Sugar Nucleotidyltransferase and Potential Drug Target Enzyme in Gram-negative Pathogens. J.Biol.Chem., 290, 2015
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4Y7V
| Structural analysis of MurU | Descriptor: | 2-acetamido-3-O-[(1R)-1-carboxyethyl]-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, GLYCEROL, IMIDODIPHOSPHORIC ACID, ... | Authors: | Renner-Schneck, M.G, Stehle, T. | Deposit date: | 2015-02-16 | Release date: | 2015-03-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structure of the N-Acetylmuramic Acid alpha-1-Phosphate (MurNAc-alpha 1-P) Uridylyltransferase MurU, a Minimal Sugar Nucleotidyltransferase and Potential Drug Target Enzyme in Gram-negative Pathogens. J.Biol.Chem., 290, 2015
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2BDF
| Src kinase in complex with inhibitor AP23451 | Descriptor: | Proto-oncogene tyrosine-protein kinase Src, {[(4-{[2-(4-AMINOCYCLOHEXYL)-9-ETHYL-9H-PURIN-6-YL]AMINO}PHENYL)(HYDROXY)PHOSPHORYL]METHYL}PHOSPHONIC ACID | Authors: | Dalgarno, D, Stehle, T, Schelling, P, Sawyer, T, Narula, S. | Deposit date: | 2005-10-20 | Release date: | 2006-10-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds. Chem.Biol.Drug Des., 67, 2006
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3EXV
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3F0Y
| Crystal structure of the human Adenovirus type 14 fiber knob | Descriptor: | Fiber protein, GLYCEROL, IMIDAZOLE | Authors: | Persson, B.D, Reiter, D.M, Arnberg, N, Stehle, T. | Deposit date: | 2008-10-27 | Release date: | 2008-11-25 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | An arginine switch in the species B adenovirus knob determines high-affinity engagement of cellular receptor CD46 J.Virol., 83, 2009
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4GR5
| Crystal structure of SlgN1deltaAsub in complex with AMPcPP | Descriptor: | CHLORIDE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, L(+)-TARTARIC ACID, ... | Authors: | Herbst, D.A, Zocher, G, Stehle, T. | Deposit date: | 2012-08-24 | Release date: | 2012-11-28 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes. J.Biol.Chem., 288, 2013
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6H5E
| Crystal Structure of the GatD/MurT Enzyme Complex from Staphylococcus aureus with bound AMPPNP | Descriptor: | DI(HYDROXYETHYL)ETHER, DUF1727 domain-containing protein, GLYCEROL, ... | Authors: | Noeldeke, E.R, Niemann, V, Stoerk, E, Stehle, T. | Deposit date: | 2018-07-24 | Release date: | 2018-09-05 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.139 Å) | Cite: | Structural basis of cell wall peptidoglycan amidation by the GatD/MurT complex of Staphylococcus aureus. Sci Rep, 8, 2018
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3EXW
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2BDJ
| Src kinase in complex with inhibitor AP23464 | Descriptor: | 3-[2-(2-CYCLOPENTYL-6-{[4-(DIMETHYLPHOSPHORYL)PHENYL]AMINO}-9H-PURIN-9-YL)ETHYL]PHENOL, Proto-oncogene tyrosine-protein kinase Src | Authors: | Dalgarno, D, Stehle, T, Schelling, P, Narula, S, Sawyer, T. | Deposit date: | 2005-10-20 | Release date: | 2006-10-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds. Chem.Biol.Drug Des., 67, 2006
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