5JQL
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![BU of 5jql by Molmil](/molmil-images/mine/5jql) | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 Void of Bound Phospholipid from Saccharomyces Cerevisiae at 2.9 Angstroms Resolution | Descriptor: | Mitochondrial distribution and morphology protein 35, Protein UPS1, mitochondrial | Authors: | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | Deposit date: | 2016-05-05 | Release date: | 2017-07-12 | Last modified: | 2020-09-02 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1 Commun Biol, 2020
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6KYL
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![BU of 6kyl by Molmil](/molmil-images/mine/6kyl) | Crystal Structure of Phosphatidic acid Transporter Ups1/Mdm35 in Complex with (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate | Descriptor: | (2R)-3-(phosphonooxy)propane-1,2-diyl dihexanoate, Mitochondrial distribution and morphology protein 35, Protein UPS1, ... | Authors: | Lu, J, Chan, K.C, Zhai, Y, Fan, J, Sun, F. | Deposit date: | 2019-09-19 | Release date: | 2019-10-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Molecular mechanism of mitochondrial phosphatidate transfer by Ups1. Commun Biol, 3, 2020
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3VT1
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![BU of 3vt1 by Molmil](/molmil-images/mine/3vt1) | Crystal structure of Ct1,3Gal43A in complex with galactose | Descriptor: | Ricin B lectin, beta-D-galactopyranose | Authors: | Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. | Deposit date: | 2012-05-18 | Release date: | 2012-12-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.187 Å) | Cite: | Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum J.Struct.Biol., 180, 2012
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3VT2
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![BU of 3vt2 by Molmil](/molmil-images/mine/3vt2) | Crystal structure of Ct1,3Gal43A in complex with isopropy-beta-D-thiogalactoside | Descriptor: | 1-methylethyl 1-thio-beta-D-galactopyranoside, GLYCEROL, Ricin B lectin | Authors: | Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. | Deposit date: | 2012-05-18 | Release date: | 2012-12-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.002 Å) | Cite: | Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum J.Struct.Biol., 180, 2012
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3VT0
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![BU of 3vt0 by Molmil](/molmil-images/mine/3vt0) | Crystal structure of Ct1,3Gal43A in complex with lactose | Descriptor: | GLYCEROL, Ricin B lectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. | Deposit date: | 2012-05-18 | Release date: | 2012-12-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.913 Å) | Cite: | Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum J.Struct.Biol., 180, 2012
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3VSZ
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![BU of 3vsz by Molmil](/molmil-images/mine/3vsz) | Crystal structure of Ct1,3Gal43A in complex with galactan | Descriptor: | GLYCEROL, Ricin B lectin, beta-D-galactopyranose-(1-3)-beta-D-galactopyranose, ... | Authors: | Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. | Deposit date: | 2012-05-18 | Release date: | 2012-12-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.893 Å) | Cite: | Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum J.Struct.Biol., 180, 2012
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3VSF
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![BU of 3vsf by Molmil](/molmil-images/mine/3vsf) | Crystal structure of 1,3Gal43A, an exo-beta-1,3-Galactanase from Clostridium thermocellum | Descriptor: | GLYCEROL, Ricin B lectin | Authors: | Jiang, D, Fan, J, Wang, X, Zhao, Y, Huang, B, Zhang, X.C. | Deposit date: | 2012-04-25 | Release date: | 2012-12-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.757 Å) | Cite: | Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum J.Struct.Biol., 180, 2012
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4GQ2
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![BU of 4gq2 by Molmil](/molmil-images/mine/4gq2) | S. pombe Nup120-Nup37 complex | Descriptor: | Nucleoporin nup120, Nup37 | Authors: | Liu, X, Mitchell, J, Wozniak, R, Blobel, G, Fan, J. | Deposit date: | 2012-08-22 | Release date: | 2012-10-03 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural evolution of the membrane-coating module of the nuclear pore complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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4GQ1
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![BU of 4gq1 by Molmil](/molmil-images/mine/4gq1) | Nup37 of S. pombe | Descriptor: | Nup37, SULFATE ION | Authors: | Liu, X, Mitchell, J, Wozniak, R, Blobel, G, Fan, J. | Deposit date: | 2012-08-22 | Release date: | 2012-10-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural evolution of the membrane-coating module of the nuclear pore complex. Proc.Natl.Acad.Sci.USA, 109, 2012
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4GNX
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![BU of 4gnx by Molmil](/molmil-images/mine/4gnx) | |
4GS4
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![BU of 4gs4 by Molmil](/molmil-images/mine/4gs4) | Structure of the alpha-tubulin acetyltransferase, alpha-TAT1 | Descriptor: | ACETYL COENZYME *A, Alpha-tubulin N-acetyltransferase | Authors: | Friedmann, D.R, Fan, J, Marmorstein, R. | Deposit date: | 2012-08-27 | Release date: | 2012-10-17 | Last modified: | 2013-08-28 | Method: | X-RAY DIFFRACTION (2.112 Å) | Cite: | Structure of the alpha-tubulin acetyltransferase, alpha TAT1, and implications for tubulin-specific acetylation. Proc.Natl.Acad.Sci.USA, 109, 2012
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4OR6
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![BU of 4or6 by Molmil](/molmil-images/mine/4or6) | |
4OR4
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![BU of 4or4 by Molmil](/molmil-images/mine/4or4) | |
7E2V
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![BU of 7e2v by Molmil](/molmil-images/mine/7e2v) | Crystal structure of MaDA-3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, MaDA-3 | Authors: | Gao, L, Du, X, Fan, J, Lei, X. | Deposit date: | 2021-02-07 | Release date: | 2021-12-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Enzymatic control of endo- and exo-stereoselective Diels-Alder reactions with broad substrate scope. Nat Catal, 2021
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4R43
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![BU of 4r43 by Molmil](/molmil-images/mine/4r43) | Crystal Structure Analysis of MTB PEPCK | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | Authors: | Brynda, J, Dostal, J, Pichova, I, Snasel, J, Fanfrlik, J, Machova, I. | Deposit date: | 2014-08-19 | Release date: | 2015-04-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and Functional Studies of Phosphoenolpyruvate Carboxykinase from Mycobacterium tuberculosis. Plos One, 10, 2015
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6MZL
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![BU of 6mzl by Molmil](/molmil-images/mine/6mzl) | Human TFIID canonical state | Descriptor: | TATA-box-binding protein, Transcription initiation factor TFIID subunit 1, Transcription initiation factor TFIID subunit 10, ... | Authors: | Patel, A.B, Louder, R.K, Greber, B.J, Grunberg, S, Luo, J, Fang, J, Liu, Y, Ranish, J, Hahn, S, Nogales, E. | Deposit date: | 2018-11-05 | Release date: | 2018-11-28 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Science, 362, 2018
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5LIK
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![BU of 5lik by Molmil](/molmil-images/mine/5lik) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK181 | Descriptor: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | Deposit date: | 2016-07-14 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
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5LIY
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![BU of 5liy by Molmil](/molmil-images/mine/5liy) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK204 | Descriptor: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | Deposit date: | 2016-07-15 | Release date: | 2016-10-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
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5LIX
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![BU of 5lix by Molmil](/molmil-images/mine/5lix) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK184 | Descriptor: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | Deposit date: | 2016-07-15 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
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5LIU
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![BU of 5liu by Molmil](/molmil-images/mine/5liu) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor IDD388 | Descriptor: | (2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID, 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, ... | Authors: | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | Deposit date: | 2016-07-15 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
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8CD9
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![BU of 8cd9 by Molmil](/molmil-images/mine/8cd9) | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide analog 6 | Descriptor: | 1,2-ETHANEDIOL, Cathepsin B-like peptidase (C01 family), SODIUM ION, ... | Authors: | Rubesova, P, Brynda, J, Fanfrlik, J, Gerwick, W.H, Mares, M. | Deposit date: | 2023-01-30 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Cathepsin B1 from Schistosoma mansoni in complex with gallinamide analog 6 To Be Published
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5LIW
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![BU of 5liw by Molmil](/molmil-images/mine/5liw) | Crystal structure of human AKR1B10 complexed with NADP+ and the inhibitor MK319 | Descriptor: | 1,2-ETHANEDIOL, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | Authors: | Cousido-Siah, A, Ruiz, F.X, Mitschler, A, Fanfrlik, J, Kamlar, M, Vesely, J, Hobza, P, Podjarny, A. | Deposit date: | 2016-07-15 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors. Acs Chem.Biol., 11, 2016
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4YOC
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![BU of 4yoc by Molmil](/molmil-images/mine/4yoc) | Crystal Structure of human DNMT1 and USP7/HAUSP complex | Descriptor: | DNA (cytosine-5)-methyltransferase 1, Ubiquitin carboxyl-terminal hydrolase 7, ZINC ION | Authors: | Cheng, J, Yang, H, Fang, J, Gong, R, Wang, P, Li, Z, Xu, Y. | Deposit date: | 2015-03-11 | Release date: | 2015-05-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.916 Å) | Cite: | Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation. Nat Commun, 6, 2015
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6YI7
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![BU of 6yi7 by Molmil](/molmil-images/mine/6yi7) | Structure of cathepsin B1 from Schistosoma mansoni (SmCB1) in complex with an azanitrile inhibitor | Descriptor: | 1-[(2~{S})-1-[[iminomethyl(methyl)amino]-methyl-amino]-4-methyl-1-oxidanylidene-pentan-2-yl]-3-(phenylmethyl)urea, ACETATE ION, Cathepsin B-like peptidase (C01 family) | Authors: | Jilkova, A, Rezacova, P, Pachl, P, Fanfrlik, J, Rubesova, P, Guetschow, M, Mares, M. | Deposit date: | 2020-04-01 | Release date: | 2020-12-16 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Azanitrile Inhibitors of the SmCB1 Protease Target Are Lethal to Schistosoma mansoni : Structural and Mechanistic Insights into Chemotype Reactivity. Acs Infect Dis., 7, 2021
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4GUS
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![BU of 4gus by Molmil](/molmil-images/mine/4gus) | Crystal structure of LSD2-NPAC with H3 in space group P3221 | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Histone H3.3, ... | Authors: | Chen, F, Dong, Z, Fang, J, Yang, Y, Li, Z, Xu, Y, Yang, H, Wang, P, Fang, R, Shi, Y, Xu, Y. | Deposit date: | 2012-08-29 | Release date: | 2013-01-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation Mol.Cell, 49, 2013
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