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8HJ5
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BU of 8hj5 by Molmil
Cryo-EM structure of Gq-coupled MRGPRX1 bound with Compound-16
Descriptor: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(q) subunit alpha, ...
Authors:Gan, B, Yu, L.Y, Ren, R.B.
Deposit date:2022-11-22
Release date:2023-05-31
Last modified:2023-12-13
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Mechanism of agonist-induced activation of the human itch receptor MRGPRX1.
Plos Biol., 21, 2023
6KYQ
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BU of 6kyq by Molmil
Crystal structure of DCLK1 Autoinhibited Kinase Domain
Descriptor: BETA-MERCAPTOETHANOL, Serine/threonine-protein kinase DCLK1
Authors:Yu, Y, Chen, Q.
Deposit date:2019-09-20
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.141 Å)
Cite:DCLK1 Autoinhibition and Activation in Tumorigenesis
Innovation (N Y), 2021
6KYR
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BU of 6kyr by Molmil
Crystal structure of DCLK1 mutant (P675L) Autoinhibited Kinase Domain
Descriptor: BETA-MERCAPTOETHANOL, Serine/threonine-protein kinase DCLK1
Authors:Yu, Y, Chen, Q.
Deposit date:2019-09-20
Release date:2020-09-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:DCLK1 Autoinhibition and Activation in Tumorigenesis
Innovation (N Y), 2021
6AKR
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BU of 6akr by Molmil
Crystal structure of the PDE4D catalytic domain in complex with osthole
Descriptor: 7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one, ZINC ION, cAMP-specific 3',5'-cyclic phosphodiesterase 4D
Authors:Wang, S, Huo, Y.W, Xie, Y.
Deposit date:2018-09-03
Release date:2020-02-12
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.326 Å)
Cite:Airway relaxation mechanisms and structural basis of osthole for improving lung function in asthma.
Sci.Signal., 13, 2020
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數據於2024-06-19公開中

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