5DOK
| Crystal structure of Tetrahymena p45C | Descriptor: | MAGNESIUM ION, Telomerase associated protein p45 | Authors: | Wan, B, Tang, T, Wu, J, Lei, M. | Deposit date: | 2015-09-11 | Release date: | 2015-11-25 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex Nat.Struct.Mol.Biol., 22, 2015
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5F6L
| The crystal structure of MLL1 (N3861I/Q3867L) in complex with RbBP5 and Ash2L | Descriptor: | Histone-lysine N-methyltransferase 2A, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-06 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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6AHU
| Cryo-EM structure of human Ribonuclease P with mature tRNA | Descriptor: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | Authors: | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | Deposit date: | 2018-08-20 | Release date: | 2018-12-05 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.66 Å) | Cite: | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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5F5E
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5F6K
| Crystal structure of the MLL3-Ash2L-RbBP5 complex | Descriptor: | Histone-lysine N-methyltransferase 2C, Retinoblastoma-binding protein 5, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-06 | Release date: | 2016-02-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.411 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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6AHV
| Crystal structure of human RPP40 | Descriptor: | Ribonuclease P protein subunit p40 | Authors: | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | Deposit date: | 2018-08-20 | Release date: | 2018-12-05 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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6AHR
| Cryo-EM structure of human Ribonuclease P | Descriptor: | H1 RNA, Ribonuclease P protein subunit p14, Ribonuclease P protein subunit p20, ... | Authors: | Wu, J, Niu, S, Tan, M, Lan, P, Lei, M. | Deposit date: | 2018-08-20 | Release date: | 2018-12-05 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Cryo-EM Structure of the Human Ribonuclease P Holoenzyme. Cell, 175, 2018
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4ZMI
| Crystal structure of the Helical domain of S. pombe Taz1 | Descriptor: | COBALT (II) ION, MAGNESIUM ION, Telomere length regulator taz1 | Authors: | Deng, W, Wu, J, Wang, F, Lei, M. | Deposit date: | 2015-05-04 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2. Cell Res., 25, 2015
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5F59
| The crystal structure of MLL3 SET domain | Descriptor: | Histone-lysine N-methyltransferase 2C, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | Authors: | Li, Y, Lei, M, Chen, Y. | Deposit date: | 2015-12-04 | Release date: | 2016-02-24 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structural basis for activity regulation of MLL family methyltransferases. Nature, 530, 2016
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4ZOU
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4I80
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4ZMK
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2L3N
| Solution structure of Rap1-Taz1 fusion protein | Descriptor: | DNA-binding protein rap1,Telomere length regulator taz1 | Authors: | Zhou, Z.R, Wang, F, Chen, Y, Lei, M, Hu, H. | Deposit date: | 2010-09-19 | Release date: | 2011-01-12 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nat.Struct.Mol.Biol., 18, 2011
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2SRC
| CRYSTAL STRUCTURE OF HUMAN TYROSINE-PROTEIN KINASE C-SRC, IN COMPLEX WITH AMP-PNP | Descriptor: | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, TYROSINE-PROTEIN KINASE SRC | Authors: | Xu, W, Doshi, A, Lei, M, Eck, M.J, Harrison, S.C. | Deposit date: | 1998-12-29 | Release date: | 1999-07-22 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structures of c-Src reveal features of its autoinhibitory mechanism. Mol.Cell, 3, 1999
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6AH3
| Cryo-EM structure of yeast Ribonuclease P with pre-tRNA substrate | Descriptor: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, ... | Authors: | Lan, P, Tan, M, Wu, J, Lei, M. | Deposit date: | 2018-08-16 | Release date: | 2018-10-17 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural insight into precursor tRNA processing by yeast ribonuclease P. Science, 362, 2018
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6AGB
| Cryo-EM structure of yeast Ribonuclease P | Descriptor: | RNases MRP/P 32.9 kDa subunit, Ribonuclease P RNA, Ribonuclease P protein subunit RPR2, ... | Authors: | Lan, P, Tan, M, Wu, J, Lei, M. | Deposit date: | 2018-08-10 | Release date: | 2018-10-17 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | Structural insight into precursor tRNA processing by yeast ribonuclease P. Science, 362, 2018
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4O26
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3OIQ
| Crystal structure of yeast telomere protein Cdc13 OB1 and the catalytic subunit of DNA polymerase alpha Pol1 | Descriptor: | Cell division control protein 13, DNA polymerase alpha catalytic subunit A | Authors: | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | Deposit date: | 2010-08-19 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
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3OWT
| Crystal structure of S. cerevisiae RAP1-Sir3 complex | Descriptor: | DNA-binding protein RAP1, Regulatory protein SIR3 | Authors: | Chen, Y, Yang, Y, Lei, M. | Deposit date: | 2010-09-20 | Release date: | 2011-01-12 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A conserved motif within RAP1 has diversified roles in telomere protection and regulation in different organisms. Nat.Struct.Mol.Biol., 18, 2011
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3OIP
| Crystal structure of Yeast telomere protein Cdc13 OB1 | Descriptor: | Cell division control protein 13 | Authors: | Sun, J, Yang, Y, Wan, K, Mao, N, Yu, T.Y, Lin, Y.C, DeZwaan, D.C, Freeman, B.C, Lin, J.J, Lue, N.F, Lei, M. | Deposit date: | 2010-08-19 | Release date: | 2010-11-03 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.504 Å) | Cite: | Structural bases of dimerization of yeast telomere protein Cdc13 and its interaction with the catalytic subunit of DNA polymerase alpha. Cell Res., 21, 2011
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3RSN
| Crystal Structure of the N-terminal region of Human Ash2L | Descriptor: | Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION | Authors: | Chen, Y, Wan, B, Wang, K.C, Cao, F, Yang, Y, Protacio, A, Dou, Y, Chang, H.Y, Lei, M. | Deposit date: | 2011-05-02 | Release date: | 2011-06-22 | Last modified: | 2011-12-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding. Embo Rep., 12, 2011
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5XXE
| Crystal structure of Poz1 and Tpz1 | Descriptor: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, SULFATE ION, ... | Authors: | Xue, J, Chen, H, Wu, J, Lei, M. | Deposit date: | 2017-07-03 | Release date: | 2017-12-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex. Cell Res., 27, 2017
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3RMH
| Crystal Structure of yeast telomere protein Cdc13 OB4 | Descriptor: | Yeast Cdc13 OB4 | Authors: | Sun, J, Yang, Y, Lei, M. | Deposit date: | 2011-04-20 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | Analyses of Candida Cdc13 Orthologues Revealed a Novel OB Fold Dimer Arrangement, Dimerization-Assisted DNA Binding, and Substantial Structural Differences between Cdc13 and RPA70. Mol.Cell.Biol., 32, 2012
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5XXF
| Crystal structure of Poz1, Tpz1 and Rap1 | Descriptor: | Protection of telomeres protein poz1, Protection of telomeres protein tpz1, Rap1, ... | Authors: | Xue, J, Chen, H, Wu, J, Lei, M. | Deposit date: | 2017-07-03 | Release date: | 2017-12-20 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the fission yeast S. pombe telomeric Tpz1-Poz1-Rap1 complex. Cell Res., 27, 2017
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6L7P
| cryo-EM structure of cyanobacteria NDH-1LdelV complex | Descriptor: | 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, BETA-CAROTENE, ... | Authors: | Zhang, C, Shuai, J, Wu, J, Lei, M. | Deposit date: | 2019-11-02 | Release date: | 2020-02-19 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural insights into NDH-1 mediated cyclic electron transfer. Nat Commun, 11, 2020
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