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7X3J
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BU of 7x3j by Molmil
Cryo-EM structure of human TRiC-tubulin-S2
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-01
Release date:2023-06-07
Last modified:2023-07-05
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X0S
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BU of 7x0s by Molmil
Human TRiC-tubulin-S3
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-02-22
Release date:2023-04-12
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X6Q
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BU of 7x6q by Molmil
cryo-EM structure of human TRiC-ATP-closed state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-08
Release date:2023-06-07
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7X7Y
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BU of 7x7y by Molmil
Cryo-EM structure of Human TRiC-ATP-open state
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-10
Release date:2023-06-07
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Pathway and mechanism of tubulin folding mediated by TRiC/CCT along its ATPase cycle revealed using cryo-EM.
Commun Biol, 6, 2023
7Y7M
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BU of 7y7m by Molmil
The structure of coxsackievirus A16 mature virion in complex with Fab 8C4
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-06-22
Release date:2022-08-24
Last modified:2024-11-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Molecular mechanism of antibody neutralization of coxsackievirus A16.
Nat Commun, 13, 2022
7X6O
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BU of 7x6o by Molmil
Cryo-EM structure of H1 hemagglutinin from A/Washington/05/2011 in complex with a neutralizing antibody 28-12
Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of antibody 12 fab
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-07
Release date:2022-03-23
Last modified:2024-10-30
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.
Nat Commun, 13, 2022
7X6L
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BU of 7x6l by Molmil
Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12
Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of the antibody 12 fab
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-07
Release date:2022-03-23
Last modified:2024-11-13
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.
Nat Commun, 13, 2022
4V94
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BU of 4v94 by Molmil
Molecular architecture of the eukaryotic chaperonin TRiC/CCT derived by a combination of chemical crosslinking and mass-spectrometry, XL-MS
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
Authors:Leitner, A, Joachimiak, L.A, Bracher, A, Walzthoeni, T, Chen, B, Monkemeyer, L, Pechmann, S, Holmes, S, Cong, Y, Ma, B, Ludtke, S, Chiu, W, Hartl, F.U, Aebersold, R, Frydman, J.
Deposit date:2012-01-11
Release date:2014-07-09
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:The Molecular Architecture of the Eukaryotic Chaperonin TRiC/CCT.
Structure, 20, 2012
6PWC
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BU of 6pwc by Molmil
A complex structure of arrestin-2 bound to neurotensin receptor 1
Descriptor: Beta-arrestin-1, Fab30 heavy chain, Fab30 light chain, ...
Authors:Yin, W, Li, Z, Jin, M, Yin, Y.-L, de Waal, P.W, Pal, K, Gao, X, He, Y, Gao, J, Wang, X, Zhang, Y, Zhou, H, Melcher, K, Jiang, Y, Cong, Y, Zhou, X.E, Yu, X, Xu, H.E.
Deposit date:2019-07-22
Release date:2019-12-04
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Cell Res., 29, 2019
6KS6
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BU of 6ks6 by Molmil
TRiC at 0.2 mM ADP-AlFx, Conformation 1, 0.2-C1
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ...
Authors:Jin, M, Cong, Y.
Deposit date:2019-08-23
Release date:2019-09-18
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:An ensemble of cryo-EM structures of TRiC reveal its conformational landscape and subunit specificity.
Proc.Natl.Acad.Sci.USA, 116, 2019
5H1L
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BU of 5h1l by Molmil
Crystal structure of WD40 repeat domains of Gemin5 in complex with 7-nt U4 snRNA fragment
Descriptor: GLYCEROL, Gem-associated protein 5, U4 snRNA (5'-R(*AP*UP*UP*UP*UP*UP*G)-3')
Authors:Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5H1M
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BU of 5h1m by Molmil
Crystal structure of WD40 repeat domains of Gemin5 in complex with M7G
Descriptor: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Gem-associated protein 5
Authors:Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.492 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5TSL
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BU of 5tsl by Molmil
Molecular Dynamics Flexible Fitting Model of Coxsackievirus A16 empty Procapsid VP3 Subunit
Descriptor: coxsackievirus A16
Authors:Fan, C, Cong, Y, Ye, X, Huang, Z.
Deposit date:2016-10-29
Release date:2017-02-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structural alteration and surface modifi cation of coxsackievirus A16 capsids by beta-propiolactone treatment
J.VIROL., 2017
5TSK
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BU of 5tsk by Molmil
Molecular Dynamics Flexible Fitting Model of Coxsackievirus A16 empty Procapsid VP1 Subunit
Descriptor: coxsackievirus A16 empty procapsid VP1 subunit
Authors:Fan, C, Cong, Y, Ye, X, Huang, Z.
Deposit date:2016-10-29
Release date:2017-02-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:Structural alteration and surface modifi cation of coxsackievirus A16 capsids by beta-propiolactone treatment
J.VIROL., 2017
7PG9
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BU of 7pg9 by Molmil
human 20S proteasome
Descriptor: Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ...
Authors:Xu, C, Cong, Y.
Deposit date:2021-08-13
Release date:2021-10-20
Last modified:2025-07-02
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag.
Nat Commun, 12, 2021
5ID3
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BU of 5id3 by Molmil
Solution structure of the pore-forming region of C. elegans Mitochondrial Calcium Uniporter (MCU)
Descriptor: Mitochondrial Calcium Uniporter
Authors:Oxenoid, K, Dong, Y, Cao, C, Cui, T, Sancak, Y, Markhard, A.L, Grabarek, Z, Kong, L, Liu, Z, Ouyang, B, Cong, Y, Mootha, V.K, Chou, J.J, Membrane Protein Structures by Solution NMR (MPSbyNMR)
Deposit date:2016-02-23
Release date:2016-05-04
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Architecture of the mitochondrial calcium uniporter.
Nature, 533, 2016
5H1K
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BU of 5h1k by Molmil
Crystal structure of WD40 repeat domains of Gemin5 in complex with 13-nt U4 snRNA fragment
Descriptor: Gem-associated protein 5, U4 snRNA (5'-R(*GP*CP*AP*AP*UP*UP*UP*UP*UP*GP*AP*CP*A)-3')
Authors:Wang, Y, Jin, W, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
5GW4
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BU of 5gw4 by Molmil
Structure of Yeast NPP-TRiC
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Zang, Y, Jin, M, Wang, H, Cong, Y.
Deposit date:2016-09-08
Release date:2016-10-26
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
5GW5
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BU of 5gw5 by Molmil
Structure of TRiC-AMP-PNP
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Zang, Y, Jin, M, Wang, H, Cong, Y.
Deposit date:2016-09-08
Release date:2016-10-26
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.
Nat. Struct. Mol. Biol., 23, 2016
5H1J
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BU of 5h1j by Molmil
Crystal structure of WD40 repeat domains of Gemin5
Descriptor: Gem-associated protein 5
Authors:Jin, W, Wang, Y, Liu, C.P, Yang, N, Jin, M, Cong, Y, Wang, M, Xu, R.M.
Deposit date:2016-10-10
Release date:2016-11-23
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for snRNA recognition by the double-WD40 repeat domain of Gemin5
Genes Dev., 30, 2016
8WZB
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BU of 8wzb by Molmil
RS head-neck monomer
Descriptor: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
Authors:Meng, X, Cong, Y.
Deposit date:2023-11-01
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
8X2U
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BU of 8x2u by Molmil
Radial spoke head-neck dimer
Descriptor: DPY30 domain containing 2, DnaJ homolog subfamily B member 13, Nucleoside diphosphate kinase homolog 5, ...
Authors:Meng, X, Cong, Y.
Deposit date:2023-11-10
Release date:2024-02-07
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Multi-scale structures of the mammalian radial spoke and divergence of axonemal complexes in ependymal cilia.
Nat Commun, 15, 2024
9CS3
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BU of 9cs3 by Molmil
TRiC-ADP-S2 state is a conformation when TRiC incubated in 1 mM ADP
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Jin, M, Cong, Y.
Deposit date:2024-07-23
Release date:2025-01-22
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:The conformational landscape of TRiC ring-opening and its underlying stepwise mechanism revealed by cryo-EM.
Qrb Discov, 6, 2025
9CSA
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BU of 9csa by Molmil
TRiC-ATP-AlFx
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Jin, M, Cong, Y.
Deposit date:2024-07-23
Release date:2025-01-22
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:The conformational landscape of TRiC ring-opening and its underlying stepwise mechanism revealed by cryo-EM.
Qrb Discov, 6, 2025
9CR2
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BU of 9cr2 by Molmil
TRiC-ADP-C1
Descriptor: T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, T-complex protein 1 subunit delta, ...
Authors:Jin, M, Cong, Y.
Deposit date:2024-07-20
Release date:2025-01-22
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:The conformational landscape of TRiC ring-opening and its underlying stepwise mechanism revealed by cryo-EM.
Qrb Discov, 6, 2025

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數據於2025-07-09公開中

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