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2DJK
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BU of 2djk by Molmil
Solution structure of the b' domain of thermophilic fungal protein disulfide isomerase
Descriptor: Protein disulfide-isomerase
Authors:Kato, K, Yamaguchi, Y.
Deposit date:2006-04-04
Release date:2006-04-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the b' domain of thermophilic fungal protein disulfide isomerase
To be Published
5X2B
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BU of 5x2b by Molmil
Crystal structure of mouse sulfotransferase SULT7A1 complexed with PAP
Descriptor: ADENOSINE-3'-5'-DIPHOSPHATE, CALCIUM ION, GLYCEROL, ...
Authors:Kanekiyo, M, Teramoto, T, Kakuta, Y.
Deposit date:2017-01-31
Release date:2018-03-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Crystal structure of mouse sulfotransferase SULT7A1 complexed with PAP
To Be Published
4DT2
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BU of 4dt2 by Molmil
Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment CC27209
Descriptor: (2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)methanol, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Feder, D, Hussein, W.M, Clayton, D.J, Kan, M, Schenk, G, McGeary, R.P, Guddat, L.W.
Deposit date:2012-02-20
Release date:2012-09-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
4DSY
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BU of 4dsy by Molmil
Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment CC24201
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-phenylpyridine-3-carboxylic acid, ...
Authors:Feder, D, Hussein, W.M, Clayton, D.J, Kan, M, Schenk, G, McGeary, R.P, Guddat, L.W.
Deposit date:2012-02-20
Release date:2012-09-19
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics.
Chem.Biol.Drug Des., 80, 2012
1QQL
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BU of 1qql by Molmil
THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Descriptor: FIBROBLAST GROWTH FACTOR 7/1 CHIMERA
Authors:Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
1QQK
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BU of 1qqk by Molmil
THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR)
Descriptor: FIBROBLAST GROWTH FACTOR 7
Authors:Ye, S, Luo, Y, Pelletier, H, McKeehan, W.L.
Deposit date:1999-06-07
Release date:2000-01-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
2YXZ
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BU of 2yxz by Molmil
Crystal structure of tt0281 from Thermus thermophilus HB8
Descriptor: Thiamin-monophosphate kinase
Authors:Goto, M.
Deposit date:2007-04-27
Release date:2008-04-29
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of tt0281 from Thermus thermophilus HB8
to be published
9FWG
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BU of 9fwg by Molmil
LSD1/CoREST bound to bomedemstat
Descriptor: Bomedemstat FAD adduct, Lysine-specific histone demethylase 1A, REST corepressor 1
Authors:Speranzini, V, Mattevi, A.
Deposit date:2024-06-30
Release date:2024-07-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Characterization of structural, biochemical, pharmacokinetic, and pharmacodynamic properties of the LSD1 inhibitor bomedemstat in preclinical models.
Prostate, 84, 2024
5BUP
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BU of 5bup by Molmil
Crystal structure of the ZP-C domain of mouse ZP2
Descriptor: ACETATE ION, Zona pellucida sperm-binding protein 2
Authors:Nishimura, K, Jovine, L.
Deposit date:2015-06-04
Release date:2016-01-27
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.251 Å)
Cite:A structured interdomain linker directs self-polymerization of human uromodulin.
Proc.Natl.Acad.Sci.USA, 113, 2016
4LVC
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BU of 4lvc by Molmil
Crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii in complex with adenosine
Descriptor: ACETATE ION, ADENOSINE, AMMONIUM ION, ...
Authors:Manszewski, T, Singh, K, Imiolczyk, B, Jaskolski, M.
Deposit date:2013-07-26
Release date:2014-07-30
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii.
Acta Crystallogr.,Sect.D, 71, 2015
7SCO
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BU of 7sco by Molmil
Structure of H1 influenza hemagglutinin bound to Fab 310-39G10
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 310-39G10 Fab, ...
Authors:Torrents de la Pena, A, Ward, A.B.
Deposit date:2021-09-28
Release date:2022-08-24
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus.
Immunity, 55, 2022
7SCN
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BU of 7scn by Molmil
Structure of H1 NC99 influenza hemagglutinin bound to Fab 310-63E6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 310-63E6 Fab, Heavy Chain, ...
Authors:Ward, A, Torrents de la Pena, A.
Deposit date:2021-09-28
Release date:2022-08-24
Last modified:2022-09-28
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus.
Immunity, 55, 2022
2KP1
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BU of 2kp1 by Molmil
Solution structure of the a' domain of thermophilic fungal protein disulfide isomerase
Descriptor: Protein disulfide-isomerase
Authors:Kato, K, Yamaguchi, Y, Serve, O.
Deposit date:2009-10-06
Release date:2009-10-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Redox-Dependent Domain Rearrangement of Protein Disulfide Isomerase Coupled with Exposure of Its Substrate-Binding Hydrophobic Surface
J.Mol.Biol., 2009
2KP2
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BU of 2kp2 by Molmil
Solution structure of the b' domain of thermophilic fungal protein disulfide isomerase
Descriptor: Protein disulfide-isomerase
Authors:Kato, K, Yamaguchi, Y, Serve, O.
Deposit date:2009-10-06
Release date:2009-10-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Redox-Dependent Domain Rearrangement of Protein Disulfide Isomerase Coupled with Exposure of Its Substrate-Binding Hydrophobic Surface
J.Mol.Biol., 2009
2KHA
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BU of 2kha by Molmil
Solution Structure of a Pathogen Recognition Domain from a Lepidopteran Insect, Plodia interpunctella
Descriptor: Beta-1,3-glucan-binding protein
Authors:Dai, H, Hiromasa, Y, Fabrick, J, Vandervelde, D, Kanost, M, Krishnamoorthi, R.
Deposit date:2009-03-29
Release date:2010-03-16
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:An initial event in the insect innate immune response: structural and biological studies of interactions between beta-1,3-glucan and the N-terminal domain of beta-1,3-glucan recognition protein
Biochemistry, 52, 2013
7AGH
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BU of 7agh by Molmil
Crystal structure of SF kinase YihV from E. coli in complex with AMPPNP-Mg
Descriptor: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Sulfofructose kinase
Authors:Sharma, M, Davies, G.J, Jin, Y.
Deposit date:2020-09-22
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis.
Acs Cent.Sci., 7, 2021
7AG7
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BU of 7ag7 by Molmil
Crystal structure of SFP aldolase YihT from Salmonella enterica in complex with sulfate bound at the active site
Descriptor: SULFATE ION, Sulfofructosephosphate aldolase
Authors:Sharma, M, Davies, G.J.
Deposit date:2020-09-21
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis.
Acs Cent.Sci., 7, 2021
7AG4
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BU of 7ag4 by Molmil
Crystal structure of active site mutant of SQ Isomerase (YihS-H248A) from Salmonella enterica in complex with sulfofructose (SF)
Descriptor: 6-deoxy-6-sulfo-D-fructose, Sulfoquinovose isomerase
Authors:Sharma, M, Davies, G.J.
Deposit date:2020-09-21
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis.
Acs Cent.Sci., 7, 2021
7AG1
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BU of 7ag1 by Molmil
Crystal structure of E. coli SFP aldolase (YihT) from sulfo-EMP pathway
Descriptor: 1,2-ETHANEDIOL, Sulfofructosephosphate aldolase
Authors:Sharma, M, Davies, G.J, Jin, Y.
Deposit date:2020-09-21
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis.
Acs Cent.Sci., 7, 2021
7AG6
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BU of 7ag6 by Molmil
Crystal structure of SF kinase YihV from E. coli in complex with sulfofructose (SF), ADP-Mg
Descriptor: 6-deoxy-6-sulfo-D-fructose, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Sharma, M, Davies, G.J.
Deposit date:2020-09-21
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis.
Acs Cent.Sci., 7, 2021
7AGK
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BU of 7agk by Molmil
Crystal structure of E. coli SF kinase (YihV) in complex with product sulfofructose phosphate (SFP)
Descriptor: Sulfofructose kinase, [(2~{S},3~{S},4~{S},5~{R})-3,4,5-tris(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]methanesulfonic acid
Authors:Sharma, M, Davies, G.J.
Deposit date:2020-09-22
Release date:2021-04-14
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Molecular Basis of Sulfosugar Selectivity in Sulfoglycolysis.
Acs Cent.Sci., 7, 2021
7S08
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BU of 7s08 by Molmil
Crystal structure of Epstein-Barr virus gH/gL targeting antibody 770F7
Descriptor: 770F7 Fab Heavy chain, 770F7 Fab Light chain, GLYCEROL
Authors:Chen, W.-H, Joyce, M.G.
Deposit date:2021-08-30
Release date:2022-11-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.
Immunity, 55, 2022
5AVA
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BU of 5ava by Molmil
Crystal structure of PHA-E lectin in complex with bisected glycan
Descriptor: CALCIUM ION, Erythroagglutinin, MANGANESE (II) ION, ...
Authors:Nagae, M, Yamaguchi, Y.
Deposit date:2015-06-12
Release date:2016-04-27
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Atomic visualization of a flipped-back conformation of bisected glycans bound to specific lectins
Sci Rep, 6, 2016
6P4V
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BU of 6p4v by Molmil
1.65 Angstrom ternary complex of Deoxyhypusine synthase with cofactor NAD and spermidine mimic inhibitor GC7
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1-GUANIDINIUM-7-AMINOHEPTANE, Deoxyhypusine synthase, ...
Authors:Klein, M.G, Ambrus-Aikelin, G.
Deposit date:2019-05-28
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
J.Med.Chem., 63, 2020
6PGR
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BU of 6pgr by Molmil
Cocomplex structure of Deoxyhypusine synthase with inhibitor 6-BROMO-N-(1H-INDOL-4-YL)-1-BENZOTHIOPHENE-2-CARBOXAMIDE
Descriptor: 6-bromo-N-(1H-indol-4-yl)-1-benzothiophene-2-carboxamide, Deoxyhypusine synthase
Authors:Klein, M.G, Ambrus-Aikelin, G.
Deposit date:2019-06-24
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase.
J.Med.Chem., 63, 2020

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數據於2024-08-07公開中

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