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6BIT
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BU of 6bit by Molmil
SIRPalpha antibody complex
Descriptor: KWAR23 Fab heavy chain, KWAR23 Fab light chain, Tyrosine-protein phosphatase non-receptor type substrate 1
Authors:Ring, N.G, Herndler-Brandstetter, D, Weiskopf, K, Shan, L, Volkmer, J.P, George, B.M, Lietzenmayer, M, McKenna, K.M, Naik, T.J, McCarty, A, Zheng, Y, Ring, A.M, Flavell, R.A, Weissman, I.L.
Deposit date:2017-11-03
Release date:2017-12-06
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.191 Å)
Cite:Anti-SIRP alpha antibody immunotherapy enhances neutrophil and macrophage antitumor activity.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7O1H
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BU of 7o1h by Molmil
Hybrid-2R quadruplex-duplex with (-p-p-l) topology and 3 syn residues
Descriptor: DNA (31-MER)
Authors:Mohr, S, Vianney, Y.M, Weisz, K.
Deposit date:2021-03-29
Release date:2021-05-19
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Expanding the Topological Landscape by a G-Column Flip of a Parallel G-Quadruplex.
Chemistry, 27, 2021
6ZL2
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BU of 6zl2 by Molmil
Structure of a parallel c-Myc modified with 3' duplex stem-loop overhang
Descriptor: DNA (36-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2020-06-30
Release date:2020-10-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
7PNE
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BU of 7pne by Molmil
Parallel Q-D hybrid with 3' duplex stem-loop as a lateral snapback loop
Descriptor: TTAMycdup-3sbl
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2021-09-06
Release date:2021-12-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
7PNG
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BU of 7png by Molmil
Solution structure of 1:1 complex of an indoloquinoline derivative SYUIQ-5 to parallel quadruplex-duplex (Q-D) hybrid
Descriptor: DNA (37-MER), ~{N}-(5~{H}-indolo[3,2-b]quinolin-11-yl)-~{N}',~{N}'-dimethyl-propane-1,3-diamine
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2021-09-06
Release date:2021-12-29
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Indoloquinoline Ligands Favor Intercalation at Quadruplex-Duplex Interfaces.
Chemistry, 28, 2022
8QKX
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BU of 8qkx by Molmil
Solution structure of a bimolecular quadruplex-duplex hybrid containing a V-shaped loop
Descriptor: DNA (5'-D(*CP*TP*CP*CP*AP*GP*CP*TP*GP*GP*GP*TP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*GP*GP*AP*GP*CP*TP*GP*GP*AP*GP*TP*T)-3')
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-09-18
Release date:2024-02-07
Method:SOLUTION NMR
Cite:Structural Aspects of Split G-Quadruplexes in Quadruplex-Duplex Hybrid Systems
Chemistryselect, 2024
5MCR
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BU of 5mcr by Molmil
Quadruplex with flipped tetrad formed by an artificial sequence
Descriptor: Artificial quadruplex with propeller, diagonal and lateral loop
Authors:Dickerhoff, J, Haase, L, Langel, W, Weisz, K.
Deposit date:2016-11-10
Release date:2017-04-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes.
ACS Chem. Biol., 12, 2017
8R6H
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BU of 8r6h by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology complexed with Phen-DC3
Descriptor: DNA (34-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-11-22
Release date:2024-03-06
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8RW2
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BU of 8rw2 by Molmil
Structure of a chair-type antiparallel quadruplex-duplex hybrid at pH 6
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2024-02-02
Release date:2024-03-27
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8S1W
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BU of 8s1w by Molmil
Structure of a quadruplex-duplex hybrid with a (-pd+l) loop progression
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Jana, J, Weisz, K.
Deposit date:2024-02-16
Release date:2024-03-27
Last modified:2024-06-05
Method:SOLUTION NMR
Cite:A pH-Responsive Topological Switch Based on a DNA Quadruplex-Duplex Hybrid.
Chemistry, 30, 2024
8RZX
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BU of 8rzx by Molmil
Solution structure of a parallel stranded G-quadruplex formed in ORAI1 promoter
Descriptor: DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*GP*GP*CP*AP*CP*AP*GP*GP*TP*GP*GP*GP*CP*GP*GP*GP*G)-3')
Authors:Jana, J, Weisz, K.
Deposit date:2024-02-13
Release date:2024-08-21
Last modified:2024-09-11
Method:SOLUTION NMR
Cite:Remodeling Ca 2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer.
Cell Calcium, 123, 2024
8R6D
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BU of 8r6d by Molmil
A quadruplex-duplex hybrid with a three-layered hybrid-2 G-quadruplex topology
Descriptor: DNA (31-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-11-22
Release date:2024-03-06
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
8R6G
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BU of 8r6g by Molmil
A quadruplex-duplex hybrid with a three-layered chair G-quadruplex topology
Descriptor: DNA (33-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2023-11-22
Release date:2024-03-13
Last modified:2024-07-10
Method:SOLUTION NMR
Cite:Structural Differences at Quadruplex-Duplex Interfaces Enable Ligand-Induced Topological Transitions.
Adv Sci, 11, 2024
5MBR
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BU of 5mbr by Molmil
Quadruplex with flipped tetrad formed by a human telomeric sequence
Descriptor: G-quadruplex formed by a human telomeric sequence modified with 2'-fluoro-2'-deoxyriboguanosine
Authors:Dickerhoff, J, Haase, L, Langel, W, Weisz, K.
Deposit date:2016-11-08
Release date:2017-04-19
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Tracing Effects of Fluorine Substitutions on G-Quadruplex Conformational Changes.
ACS Chem. Biol., 12, 2017
8R4E
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BU of 8r4e by Molmil
Hybrid-1R G-quadruplex with a +(lpp) loop progression
Descriptor: DNA (27-MER)
Authors:Jana, J, Vianney, Y.M, Weisz, K.
Deposit date:2023-11-13
Release date:2023-12-27
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
8R4W
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BU of 8r4w by Molmil
(3+1) hybrid-2 G-quadruplex with a -(llp) loop progression
Descriptor: DNA (25-MER)
Authors:Jana, J, Vianney, Y.M, Weisz, K.
Deposit date:2023-11-14
Release date:2023-12-27
Last modified:2024-01-31
Method:SOLUTION NMR
Cite:Impact of loop length and duplex extensions on the design of hybrid-type G-quadruplexes.
Chem.Commun.(Camb.), 60, 2024
7ATZ
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BU of 7atz by Molmil
G-quadruplex with V-shaped loop from the first repeat of KCNN4 minisatellite
Descriptor: DNA (5'-D(*GP*GP*TP*CP*TP*GP*AP*GP*GP*GP*AP*GP*AP*GP*GP*GP*GP*CP*TP*GP*GP*GP*T)-3')
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2020-11-02
Release date:2021-04-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:First Tandem Repeat of a Potassium Channel KCNN4 Minisatellite Folds into a V-Loop G-Quadruplex Structure.
Biochemistry, 60, 2021
7ZEM
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BU of 7zem by Molmil
Structure of a parallel G-quadruplex with a snapback loop
Descriptor: DNA (5'-D(*(DT5)P*GP*GP*CP*TP*AP*GP*GP*GP*TP*CP*AP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
Authors:Jana, J, Vianney, Y.M, Schroeder, N, Weisz, K.
Deposit date:2022-03-31
Release date:2022-06-15
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Guiding the folding of G-quadruplexes through loop residue interactions.
Nucleic Acids Res., 50, 2022
7ZEO
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BU of 7zeo by Molmil
Structure of a hybrid-type G-quadruplex with a snapback loop and an all-syn G-column (hybrid-1R)
Descriptor: DNA (5'-D(*(DG5)P*(BGM)P*CP*TP*AP*GP*GP*GP*TP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
Authors:Jana, J, Vianney, Y.M, Schroeder, N, Weisz, K.
Deposit date:2022-03-31
Release date:2022-06-15
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Guiding the folding of G-quadruplexes through loop residue interactions.
Nucleic Acids Res., 50, 2022
7ZEK
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BU of 7zek by Molmil
Structure of a hybrid-type G-quadruplex with a snapback loop (hybrid 1R')
Descriptor: DNA (5'-D(*(DG5)P*GP*CP*TP*AP*(BG)P*GP*GP*TP*CP*AP*GP*GP*GP*TP*GP*GP*GP*TP*CP*AP*(DG3))-3')
Authors:Jana, J, Vianney, Y.M, Schroeder, N, Weisz, K.
Deposit date:2022-03-31
Release date:2022-06-22
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Guiding the folding of G-quadruplexes through loop residue interactions.
Nucleic Acids Res., 50, 2022
6ZTE
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BU of 6zte by Molmil
Structure of a parallel c-myc modified with 5' duplex stem-loop and 3' diagonal snap-back loop
Descriptor: DNA (36-MER)
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2020-07-20
Release date:2020-10-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Quadruplex-Duplex Junction: A High-Affinity Binding Site for Indoloquinoline Ligands.
Chemistry, 26, 2020
8ABD
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BU of 8abd by Molmil
Solution structure of Phen-DC3 intercalating into a quadruplex-duplex hybrid
Descriptor: DNA (36-MER), N2,N9-bis(1-methylquinolin-3-yl)-1,10-phenanthroline-2,9-dicarboxamide
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2022-07-04
Release date:2022-11-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception.
Nucleic Acids Res., 50, 2022
8ABN
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BU of 8abn by Molmil
Solution structure of a phenyl-indoloquinoline intercalating into a quadruplex-duplex hybrid
Descriptor: DNA (27-MER), diethyl-[3-[[4-(4,5,9-trimethyl-10H-indolo[3,2-b]quinolin-5-ium-11-yl)phenyl]carbonylamino]propyl]azanium
Authors:Vianney, Y.M, Weisz, K.
Deposit date:2022-07-04
Release date:2022-11-16
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:High-affinity binding at quadruplex-duplex junctions: rather the rule than the exception.
Nucleic Acids Res., 50, 2022
6F4Z
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BU of 6f4z by Molmil
2'F-araG modified quadruplex with flipped G-tract and central tetrad
Descriptor: DNA (5'-D(*GP*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*(GFL)P*GP*GP*AP*CP*GP*GP*G)-3')
Authors:Dickerhoff, J, Weisz, K.
Deposit date:2017-11-30
Release date:2018-04-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Fluorine-Mediated Editing of a G-Quadruplex Folding Pathway.
Chembiochem, 19, 2018
6FFR
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BU of 6ffr by Molmil
DNA-RNA Hybrid Quadruplex with Flipped Tetrad
Descriptor: DNA/RNA (5'-R(*G)-D(P*GP*GP*AP*TP*GP*GP*GP*AP*CP*AP*CP*AP*GP*GP*GP*GP*AP*C)-R(P*G)-D(P*GP*G)-3')
Authors:Haase, L, Dickerhoff, J, Weisz, K.
Deposit date:2018-01-09
Release date:2018-09-26
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:DNA-RNA Hybrid Quadruplexes Reveal Interactions that Favor RNA Parallel Topologies.
Chemistry, 24, 2018

226707

數據於2024-10-30公開中

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