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5FWC
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BU of 5fwc by Molmil
Human Spectrin SH3 domain D48G, E7A, K60A
Descriptor: 1,2-ETHANEDIOL, AMMONIUM ION, SPECTRIN ALPHA CHAIN, ...
Authors:Gallego, P, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Human Spectrin SH3 Domain D48G, E7A, K60A
To be Published
5FO2
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BU of 5fo2 by Molmil
Structure of human transthyretin mutant A108I
Descriptor: TRANSTHYRETIN
Authors:Varejao, N, Santanna, R, Saraiva, M.J, Gallego, P, Ventura, S, Reverter, D.
Deposit date:2015-11-17
Release date:2016-11-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
6FWW
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BU of 6fww by Molmil
GFP/KKK. A redesigned GFP with improved solubility
Descriptor: Green fluorescent protein
Authors:Varejao, N, Lascorz, J, Gil-Garcia, M, Diaz-Caballero, M, Navarro, S, Ventura, S, Reverter, D.
Deposit date:2018-03-07
Release date:2018-08-01
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.131 Å)
Cite:Combining Structural Aggregation Propensity and Stability Predictions To Redesign Protein Solubility.
Mol. Pharm., 15, 2018
5FW8
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BU of 5fw8 by Molmil
Structure of human transthyretin mutant E89K
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2016-12-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
5FW7
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BU of 5fw7 by Molmil
Structure of human transthyretin mutant A109V
Descriptor: TRANSTHYRETIN
Authors:Gallego, P, Varejao, N, Santanna, R, Saraiva, M.J, Ventura, S, Reverter, D.
Deposit date:2016-02-12
Release date:2017-03-08
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structure of New Non-Amyloidogenic Mutant of Ttr A108V
To be Published
6FXU
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BU of 6fxu by Molmil
Crystal structure of human transthyretin mutant T119M at pH 5.5
Descriptor: Transthyretin
Authors:Varejao, N, Esperante, S, Ventura, S, Reverter, D.
Deposit date:2018-03-09
Release date:2019-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.359 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6FZL
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BU of 6fzl by Molmil
Crystal structure of human transthyretin double mutant K35T/T119M
Descriptor: Transthyretin
Authors:Esperante, S, Ventura, S, Reverter, D, Varejao, N.
Deposit date:2018-03-15
Release date:2019-03-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.446 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
6FWD
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BU of 6fwd by Molmil
Crystal structure of human transthyretin double mutant R34G/T119M at pH 5.5
Descriptor: Transthyretin
Authors:Esperante, S, Ventura, S, Reverter, D, Varejao, N.
Deposit date:2018-03-06
Release date:2019-03-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.
J.Biol.Chem., 297, 2021
1H8K
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BU of 1h8k by Molmil
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25V, V53I, V58L MUTANT
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Serrano, L.
Deposit date:2001-02-09
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E6H
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BU of 1e6h by Molmil
A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
Descriptor: SPECTRIN ALPHA CHAIN
Authors:Vega, M.C, Serrano, L.
Deposit date:2000-08-17
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
1E6G
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BU of 1e6g by Molmil
A-SPECTRIN SH3 DOMAIN A11V, V23L, M25I, V53I, V58L MUTANT
Descriptor: SPECTRIN ALPHA CHAIN, SULFATE ION
Authors:Vega, M.C, Serrano, L.
Deposit date:2000-08-15
Release date:2002-05-23
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
9B73
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BU of 9b73 by Molmil
Cryo-EM structure of the desensitised ATP-bound human P2X1 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Felix, M.B, Alisa, G, Hariprasad, V, Jesse, I.M, David, M.T.
Deposit date:2024-03-27
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (1.96 Å)
Cite:Structural insights into the human P2X1 receptor and ligand interactions
Nat Commun, 15, 2024
9B95
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BU of 9b95 by Molmil
Cryo-EM structure of the closed NF449-bound human P2X1 receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4,4',4'',4'''-{carbonylbis[azanediylbenzene-5,1,3-triylbis(carbonylazanediyl)]}tetra(benzene-1,3-disulfonic acid), P2X purinoceptor 1
Authors:Felix, M.B, Alisa, G, Hariprasad, V, Jesse, I.M, David, M.T.
Deposit date:2024-04-01
Release date:2024-10-09
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural insights into the human P2X1 receptor and ligand interactions
Nat Commun, 15, 2024
2KMQ
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BU of 2kmq by Molmil
Solution structure of intermediate IIb of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2K2Z
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BU of 2k2z by Molmil
Solution structure of the folded domain of intermediate IIIb of Tick Carboxypeptidase Inhibitor
Descriptor: Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D, Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2K2X
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BU of 2k2x by Molmil
Solution Structure of Tick Carboxypeptidase Inhibitor at pH 3.5
Descriptor: Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D, Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2KMP
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BU of 2kmp by Molmil
Solution structure of intermeidate IIa of Leeck-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2K2Y
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BU of 2k2y by Molmil
Solution structure of the folded domain of intermediate IIIa of Tick Carboxypeptidase Inhibitor
Descriptor: Carboxypeptidase inhibitor
Authors:Pantoja-Uceda, D, Blanco, F.
Deposit date:2008-04-15
Release date:2009-01-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:The NMR structures of the major intermediates of the two-domain tick carboxypeptidase inhibitor reveal symmetry in its folding and unfolding pathways.
J.Biol.Chem., 283, 2008
2KMO
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BU of 2kmo by Molmil
Solution structure of native Leech-derived tryptase inhibitor, LDTI
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
2KMR
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BU of 2kmr by Molmil
Solution structure of intermediate IIc of Leech-derived tryptase inhibitor, LDTI.
Descriptor: Leech-derived tryptase inhibitor C
Authors:Pantoja-Uceda, D, Santoro, J.
Deposit date:2009-08-03
Release date:2009-11-10
Last modified:2011-08-10
Method:SOLUTION NMR
Cite:Deciphering the structural basis that guides the oxidative folding of leech-derived tryptase inhibitor.
J.Biol.Chem., 284, 2009
1PYT
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BU of 1pyt by Molmil
TERNARY COMPLEX OF PROCARBOXYPEPTIDASE A, PROPROTEINASE E, AND CHYMOTRYPSINOGEN C
Descriptor: CALCIUM ION, CHYMOTRYPSINOGEN C, PROCARBOXYPEPTIDASE A, ...
Authors:Gomis-Ruth, F.X, Gomez, M, Bode, W, Huber, R, Aviles, F.X.
Deposit date:1995-06-21
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The three-dimensional structure of the native ternary complex of bovine pancreatic procarboxypeptidase A with proproteinase E and chymotrypsinogen C.
EMBO J., 14, 1995
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數據於2024-10-16公開中

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