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Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with RU39411
Descriptor:	11alpha-{4-[2-(dimethylamino)ethoxy]phenyl}estra-1(10),2,4-triene-3,17beta-diol, Estrogen receptor
Authors:	Fanning, S.W, Greene, G.L.
Deposit date:	2022-03-30
Release date:	2022-05-04
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (1.68 Å)
Cite:	Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022

Estrogen Receptor Alpha Ligand Binding Domain Y537S in Complex with LSZ102
Descriptor:	Estrogen receptor, LSZ102
Authors:	Fanning, S.W, Greene, G.L.
Deposit date:	2019-12-12
Release date:	2019-12-25
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022

Estrogen Receptor Alpha Ligand Binding Domain in Complex with the Selective Estrogen Receptor Modulator Clomiphene
Descriptor:	Clomifene, Estrogen receptor
Authors:	Fanning, S.W, Greene, G.L.
Deposit date:	2020-02-03
Release date:	2020-09-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	Stereospecific lasofoxifene derivatives reveal the interplay between estrogen receptor alpha stability and antagonistic activity in ESR1 mutant breast cancer cells. Elife, 11, 2022