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Cryo-EM structure for mouse leptin in complex with the mouse LEP-R ectodomain (1:2 mLEP:mLEPR model).
Descriptor:	Leptin, Leptin receptor
Authors:	Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
Deposit date:	2022-08-26
Release date:	2023-04-05
Last modified:	2023-07-26
Method:	ELECTRON MICROSCOPY (4.43 Å)
Cite:	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023

Cryo-EM structure for the mouse LEPR-CRH2:Leptin:LEPR-Ig complex following symmetry expansion in combination with local refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Leptin, Leptin receptor
Authors:	Verstraete, K, Savvides, S.N, Verschueren, K.G, Tsirigotaki, A.
Deposit date:	2022-09-30
Release date:	2023-04-05
Last modified:	2023-04-26
Method:	ELECTRON MICROSCOPY (4.02 Å)
Cite:	Mechanism of receptor assembly via the pleiotropic adipokine Leptin. Nat.Struct.Mol.Biol., 30, 2023