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7ZXF
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BU of 7zxf by Molmil
Pfs48/45 bound to monoclonal antibodies 10D8 and 85RF45.1
Descriptor: 10D8 heavy chain, 10D8 light chain, 85RF45.1 heavy chain, ...
Authors:Ko, K.T, Lennartz, F.L, Higgins, M.K.
Deposit date:2022-05-20
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.72 Å)
Cite:Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZWF
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BU of 7zwf by Molmil
Pfs48/45 bound to scFv fragment of monoclonal antibody 32F3
Descriptor: 32F3scFv, Gametocyte surface protein P45/48, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Ko, K.T, Lennartz, F.L, Higgins, M.K.
Deposit date:2022-05-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.132 Å)
Cite:Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZWM
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BU of 7zwm by Molmil
Pfs48/45 central and C-terminal domains bound to Fab fragments of monoclonal antibody 10D8 and 32F3
Descriptor: 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ko, K.T, Lennartz, F.L, Higgins, M.K.
Deposit date:2022-05-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.69 Å)
Cite:Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZWI
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BU of 7zwi by Molmil
Pfs48/45 C-terminal domain bound to fab fragment of monoclonal antibody 32F3
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 32F3 heavy chain, 32F3 light chain, ...
Authors:Ko, K.T, Lennartz, F.L, Higgins, M.K.
Deposit date:2022-05-19
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
7ZXG
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BU of 7zxg by Molmil
Pfs48/45 bound to Fab fragment of monoclonal antibody 10D8
Descriptor: 10D8 heavy chain, 10D8 light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Ko, K.T, Lennartz, F.L, Higgins, M.K.
Deposit date:2022-05-20
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Structure of the malaria vaccine candidate Pfs48/45 and its recognition by transmission blocking antibodies.
Nat Commun, 13, 2022
8DFG
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BU of 8dfg by Molmil
Crystal structure of potently neutralizing human monoclonal antibody 42D6 Fab in complex with MSP1-19
Descriptor: 42D6 Fab Heavy Chain, 42D6 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFH
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BU of 8dfh by Molmil
Crystal structure of non-neutralizing / interfering human monoclonal antibody 42C3 Fab in complex with MSP1-19
Descriptor: 42C3 Fab Heavy Chain, 42C3 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8DFI
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BU of 8dfi by Molmil
Crystal structure of moderately neutralizing / interfering human monoclonal antibody 42C11 Fab in complex with MSP1-19
Descriptor: 42C11 Fab Heavy Chain, 42C11 Fab Light Chain, Merozoite surface protein 1
Authors:Patel, P.N, Tang, W.K, Tolia, N.H.
Deposit date:2022-06-22
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion.
Nat Commun, 13, 2022
8QKS
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BU of 8qks by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to R5.034
Descriptor: Immunoglobulin lambda variable 1-36, R5034HV, Reticulocyte-binding protein-like protein 5
Authors:Wright, N.D, Barrett, J.R, Bradshaw, W.J, Paterson, N.G, MacLean, E.M, Ferreira, L, McHugh, K, Von Delft, F, Koekemoer, L, Draper, S.J.
Deposit date:2023-09-16
Release date:2024-07-31
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (3.994 Å)
Cite:Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Cell, 2024
8QKR
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BU of 8qkr by Molmil
Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to R5.251
Descriptor: R5251VHCH, R5251VLCL, Reticulocyte-binding protein-like protein 5
Authors:Wright, N.D, Barrett, J.R, Bradshaw, W.J, Paterson, N.G, MacLean, E.M, Ferreira, L, McHugh, K, Koekemoer, L, Draper, S.J.
Deposit date:2023-09-16
Release date:2024-07-31
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (3.234 Å)
Cite:Analysis of the diverse antigenic landscape of the malaria protein RH5 identifies a potent vaccine-induced human public antibody clonotype.
Cell, 2024
6H5N
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BU of 6h5n by Molmil
Plasmodium falciparum Pfs48/45 C-terminal domain bound to monoclonal antibody 85RF45.1
Descriptor: Antibody 85RF45.1 heavy chain, Antibody 85RF45.1 light chain, Gametocyte surface protein P45/48
Authors:Lennartz, F, Higgins, M.K.
Deposit date:2018-07-25
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.23 Å)
Cite:Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody.
Nat Commun, 9, 2018
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數據於2024-09-04公開中

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