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8C8C
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BU of 8c8c by Molmil
Crystal Structure of Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (PI5P4Ka) bound to an inhibitor
Descriptor: Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, ~{N}-(3-chloranyl-4-methoxy-phenyl)-7-(3,4-dimethylphenyl)pyrrolo[2,3-d]pyrimidin-4-amine
Authors:Harborne, S.P.D, Howard, T.D, Ogg, D.T.
Deposit date:2023-01-19
Release date:2023-04-26
Last modified:2024-06-19
Method:X-RAY DIFFRACTION (2.096 Å)
Cite:Identification of ARUK2002821 as an isoform-selective PI5P4K alpha inhibitor.
Rsc Med Chem, 14, 2023
5BNC
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BU of 5bnc by Molmil
Structure of heme binding protein MSMEG_6519 from Mycobacterium smegmatis
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, MAGNESIUM ION, NICKEL (II) ION, ...
Authors:Ahmed, F.H, Carr, P.D, Jackson, C.J.
Deposit date:2015-05-26
Release date:2015-10-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria.
J.Mol.Biol., 427, 2015
6ECI
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BU of 6eci by Molmil
Structure of the FAD binding protein MSMEG_5243 from Mycobacterium smegmatis
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Pyridoxamine 5'-phosphate oxidase-related, ...
Authors:Ahmed, F.H, Antoney, J, Carr, P.D, Jackson, C.J.
Deposit date:2018-08-07
Release date:2018-12-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:FAD-sequestering proteins protect mycobacteria against hypoxic and oxidative stress.
J. Biol. Chem., 294, 2019
8BQ4
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BU of 8bq4 by Molmil
Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an inhibitor
Descriptor: 6-methyl-~{N}-(4-methylsulfonylphenyl)thieno[2,3-d]pyrimidin-4-amine, Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma
Authors:Ogg, D.J, Howard, T.D.
Deposit date:2022-11-18
Release date:2022-12-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:The Identification of Potent, Selective, and Brain Penetrant PI5P4K gamma Inhibitors as In Vivo-Ready Tool Molecules.
J.Med.Chem., 66, 2023
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數據於2024-08-14公開中

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