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6EE0
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BU of 6ee0 by Molmil
Crystal Structure of SNX23 PX domain
Descriptor: Kinesin-like protein KIF16B
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-12
Release date:2018-08-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.518 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6H7W
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BU of 6h7w by Molmil
Model of retromer-Vps5 complex assembled on membrane.
Descriptor: Putative vacuolar protein sorting-associated protein, Vacuolar protein sorting-associated protein 26-like protein, Vacuolar protein sorting-associated protein 29, ...
Authors:Kovtun, O, Leneva, N, Ariotti, N, Rohan, T.S, Owen, D.J, Briggs, J.A.G, Collins, B.M.
Deposit date:2018-07-31
Release date:2018-09-26
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (11.4 Å)
Cite:Structure of the membrane-assembled retromer coat determined by cryo-electron tomography.
Nature, 561, 2018
6XS7
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BU of 6xs7 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D2
Descriptor: 48V-DTY-THR-THR-ILE-TYR-TRP-THR-PRO-LEU-GLY-THR-PHE-PRO-ARG-ILE-ARG, FORMIC ACID, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XSA
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BU of 6xsa by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L2
Descriptor: 48V-TYR-LEU-PRO-THR-ILE-THR-GLY-VAL-GLY-HIS-LEU-TRP-HIS-PRO-LEU, SULFATE ION, Vacuolar protein sorting-associated protein 29
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS5
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BU of 6xs5 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-D1
Descriptor: 48V-DTY-ILE-ILE-ASP-THR-PRO-LEU-GLY-VAL-PHE-LEU-SER-SER-LEU-LYS-ARG, FORMIC ACID, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS8
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BU of 6xs8 by Molmil
Crystal structure of Chaetomium thermophilum Vps29 complexed with RaPID-derived cyclic peptide RT-D3
Descriptor: 48V-DTY-GLY-TYR-ASP-PRO-LEU-GLY-LEU-LYS-TYR-PHE-ALA, Vacuolar protein sorting-associated protein 29
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-14
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95009851 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6XS9
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BU of 6xs9 by Molmil
Crystal structure of human Vps29 complexed with RaPID-derived cyclic peptide RT-L1
Descriptor: 1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE, 48V-TYR-ILE-LYS-THR-PRO-LEU-GLY-THR-PHE-PRO-ASN-ARG-HIS-GLY, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2020-07-15
Release date:2021-07-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex.
Sci Adv, 7, 2021
6ECM
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BU of 6ecm by Molmil
Crystal Structure of SNX15 PX domain in domain swapped conformation
Descriptor: SULFATE ION, Sorting nexin-15
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-08
Release date:2018-08-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.353 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
6MBI
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BU of 6mbi by Molmil
Crystal Structure of SNX15 PX domain in domain swapped conformation form 2
Descriptor: Sorting nexin-15
Authors:Chandra, M, Collins, B.M.
Deposit date:2018-08-29
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:Classification of the human phox homology (PX) domains based on their phosphoinositide binding specificities.
Nat Commun, 10, 2019
8F2R
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BU of 8f2r by Molmil
Human CCC complex
Descriptor: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
Authors:Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J.
Deposit date:2022-11-08
Release date:2023-05-24
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.12 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8F2U
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BU of 8f2u by Molmil
Human CCC complex
Descriptor: COMM domain-containing protein 1, COMM domain-containing protein 10, COMM domain-containing protein 2, ...
Authors:Healy, M.D, McNally, K.E, Butkovic, R, Chilton, M, Kato, K, Sacharz, J, McConville, C, Moody, E.R.R, Shaw, S, Planelles-Herrero, V.J, Kadapalakere, S.Y, Ross, J, Borucu, U, Palmer, C.S, Chen, K, Croll, T.I, Hall, R.J, Caruana, N.J, Ghai, R, Nguyen, T.H.D, Heesom, K.J, Saitoh, S, Berger, I, Berger-Schaffitzel, C, Williams, T.A, Stroud, D.A, Derivery, E, Collins, B.M, Cullen, P.J.
Deposit date:2022-11-08
Release date:2023-05-24
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8TTT
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BU of 8ttt by Molmil
Structure of SNX27 FERM complexed with Fam21A repeat 15 (1124-1140)
Descriptor: DI(HYDROXYETHYL)ETHER, Fam21A repeat 15 peptide, GLYCEROL, ...
Authors:Guo, Q, Chen, K.-E, Collins, B.M.
Deposit date:2023-08-15
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTV
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BU of 8ttv by Molmil
Structure of SNX27 FERM complexed with Fam21A repeat 20 (1289-1302)
Descriptor: DI(HYDROXYETHYL)ETHER, Fam21A repeat 20 peptide, Sorting nexin-27
Authors:Guo, Q, Chen, K.-E, Collins, B.M.
Deposit date:2023-08-15
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTU
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BU of 8ttu by Molmil
Structure of SNX27 FERM complexed with Fam21A repeat 19 (1261 - 1274)
Descriptor: DI(HYDROXYETHYL)ETHER, Fam21A repeat 19 peptide, GLYCEROL, ...
Authors:Guo, Q, Chen, K.-E, Collins, B.M.
Deposit date:2023-08-15
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTD
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BU of 8ttd by Molmil
Structure of VPS29 complexed with Fam21A repeat 21 (1328-1341)
Descriptor: FORMIC ACID, SER-ASN-ILE-PHE-ASP-ASP-PRO-LEU-ASN-ALA-PHE-GLY-GLY-GLN, Vacuolar protein sorting-associated protein 29
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2023-08-13
Release date:2024-08-21
Method:X-RAY DIFFRACTION (2.011 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTA
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BU of 8tta by Molmil
Structure of retromer VPS29-VPS35 (483-796) complexed with Fam21A repeat 21 (1328-1341)
Descriptor: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2023-08-13
Release date:2024-08-21
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTC
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BU of 8ttc by Molmil
Structure of retromer VPS29-VPS35 (483-796) complexed with Fam21A repeat 20 (1289-1302)
Descriptor: ACETATE ION, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Chen, K.-E, Guo, Q, Collins, B.M.
Deposit date:2023-08-13
Release date:2024-08-21
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.
Proc.Natl.Acad.Sci.USA, 121, 2024
8ESD
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BU of 8esd by Molmil
Crystal structure of COMMD7-COMMD9-COMMD5-COMMD10 tetramer
Descriptor: COMM domain-containing protein 10, COMM domain-containing protein 5, COMM domain-containing protein 7, ...
Authors:Healy, M.D, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8ESE
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BU of 8ese by Molmil
Crystal structure of human Vps29 bound to a peptide from Vps35L
Descriptor: VPS35 endosomal protein-sorting factor-like, Vacuolar protein sorting-associated protein 29
Authors:Healy, M.D, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-05-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Cell, 186, 2023
8ESF
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BU of 8esf by Molmil
Crystal structure of human Nischarin PX and LRR domains with engineered mutations
Descriptor: IMIDAZOLE, Nischarin
Authors:Eldershaw, D.E, Collins, B.M.
Deposit date:2022-10-13
Release date:2023-10-25
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Crystal structure of human Nischarin PX and LRR domains with engineered mutations
To Be Published
4GXB
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BU of 4gxb by Molmil
Structure of the SNX17 atypical FERM domain bound to the NPxY motif of P-selectin
Descriptor: GLYCEROL, P-selectin, Sorting nexin-17
Authors:Ghai, R, Bugarcic, A, Liu, H, Norwood, S.J, Li, S.S, Teasdale, R.D, Collins, B.M.
Deposit date:2012-09-04
Release date:2013-03-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.
Proc.Natl.Acad.Sci.USA, 110, 2013
4Z8J
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BU of 4z8j by Molmil
Crystal structure of the SNX27 PDZ domain bound to the C-terminal PTHR PDZ binding motif
Descriptor: C-terminal PDZ binding motif from parathyroid hormone receptor (PTHR), Sorting nexin-27
Authors:Clairfeuille, T, Pavlos, N, Collins, B.M.
Deposit date:2015-04-09
Release date:2016-02-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Role of SNX27-retromer in PTHR trafficking
To Be Published
4QKV
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BU of 4qkv by Molmil
Crystal structure of the mouse cavin1 HR1 domain
Descriptor: Polymerase I and transcript release factor
Authors:Kovtun, O, Tillu, V, Parton, R.G, Collins, B.M.
Deposit date:2014-06-10
Release date:2015-03-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural insights into the organization of the cavin membrane coat complex
Dev.Cell, 31, 2014
7RM8
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BU of 7rm8 by Molmil
Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide
Descriptor: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion
Authors:Healy, M.D, Collins, B.M, Mobli, M.
Deposit date:2021-07-26
Release date:2022-08-31
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins.
Structure, 30, 2022
4QKW
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BU of 4qkw by Molmil
Crystal structure of the zebrafish cavin4a HR1 domain
Descriptor: CHLORIDE ION, Muscle-related coiled-coil protein
Authors:Kovtun, O, Tillu, V, Parton, R.G, Collins, B.M.
Deposit date:2014-06-10
Release date:2015-03-18
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural insights into the organization of the cavin membrane coat complex
Dev.Cell, 31, 2014

224201

數據於2024-08-28公開中

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