6FF9
 
 | | Mutant R280K of human P53 | | Descriptor: | Cellular tumor antigen p53, ZINC ION | | Authors: | Trovao, F.G, Gomes, A.S, Pinheiro, B, Carvalho, A.L, Romao, M.J. | | Deposit date: | 2018-01-04 | | Release date: | 2018-04-25 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding.
Int J Mol Sci, 19, 2018
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6G0V
 | | Human Galectin-3 in complex with a TF tumor-associated antigen mimetic | | Descriptor: | (3~{R},5~{R},6~{S},7~{S},8~{R},13~{S})-5-(hydroxymethyl)-7-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-6-oxidanyl-11-oxidanylidene-2,4-dioxa-9-thia-12-azatricyclo[8.4.0.0^{3,8}]tetradec-1(10)-ene-13-carboxylic acid, CHLORIDE ION, Galectin-3 | | Authors: | Trovao, F.G, Santarsia, S, Carvalho, A.L. | | Deposit date: | 2018-03-19 | | Release date: | 2018-08-22 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.09 Å) | | Cite: | Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3.
ChemMedChem, 13, 2018
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6FOP
 | | Glycoside hydrolase family 81 from Clostridium thermocellum (CtLam81A), Mutant E515A | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CALCIUM ION, ... | | Authors: | Correia, M.A.S.C, Carvalho, A.L. | | Deposit date: | 2018-02-08 | | Release date: | 2019-03-13 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Novel insights into the degradation of beta-1,3-glucans by the cellulosome of Clostridium thermocellum revealed by structure and function studies of a family 81 glycoside hydrolase.
Int.J.Biol.Macromol., 117, 2018
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1Y07
 | | Crystal structure of the superoxide reductase from Treponema pallidum | | Descriptor: | FE (III) ION, MAGNESIUM ION, desulfoferrodoxin (rbo) | | Authors: | Santos-Silva, T, Trincao, J, Carvalho, A.L, Bonifacio, C, Auchere, F, Moura, J, Romao, M.J. | | Deposit date: | 2004-11-15 | | Release date: | 2005-11-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | The first crystal structure of class III superoxide reductase from Treponema pallidum.
J.Biol.Inorg.Chem., 11, 2006
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6R31
 | | Family 11 Carbohydrate-Binding Module from Clostridium thermocellum in complex with beta-1,3-1,4-mixed-linked tetrasaccharide | | Descriptor: | CALCIUM ION, Endoglucanase H, PHOSPHATE ION, ... | | Authors: | Ribeiro, D.O, Carvalho, A.L. | | Deposit date: | 2019-03-19 | | Release date: | 2020-02-05 | | Last modified: | 2024-05-15 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Molecular basis for the preferential recognition of beta 1,3-1,4-glucans by the family 11 carbohydrate-binding module from Clostridium thermocellum.
Febs J., 287, 2020
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6R3M
 | | Family 11 Carbohydrate-Binding Module from Clostridium thermocellum in complex with beta-1,3-1,4-mixed-linked tetrasaccharide | | Descriptor: | ACETATE ION, CALCIUM ION, Endoglucanase H, ... | | Authors: | Ribeiro, D.O, Carvalho, A.L. | | Deposit date: | 2019-03-20 | | Release date: | 2020-02-05 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Molecular basis for the preferential recognition of beta 1,3-1,4-glucans by the family 11 carbohydrate-binding module from Clostridium thermocellum.
Febs J., 287, 2020
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7NOX
 | | Structure of SGBP BO2743 from Bacteroides ovatus in complex with mixed-linked gluco-nonasaccharide | | Descriptor: | AZIDE ION, GLYCEROL, MAGNESIUM ION, ... | | Authors: | Correia, V.C, Trovao, F, Pinheiro, B.A, Palma, A.S, Carvalho, A.L. | | Deposit date: | 2021-02-26 | | Release date: | 2021-11-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.43 Å) | | Cite: | Mapping Molecular Recognition of beta 1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus.
Microbiol Spectr, 9, 2021
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7O8C
 | | Structure of SGBP BO2743 from Bacteroides ovatus | | Descriptor: | 2-HYDROXYETHYL DISULFIDE, AZIDE ION, BETA-MERCAPTOETHANOL, ... | | Authors: | Correia, V.C, Trovao, F, Pinheiro, B.A, Palma, A.S, Carvalho, A.L. | | Deposit date: | 2021-04-15 | | Release date: | 2021-12-08 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mapping Molecular Recognition of beta 1,3-1,4-Glucans by a Surface Glycan-Binding Protein from the Human Gut Symbiont Bacteroides ovatus.
Microbiol Spectr, 9, 2021
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3UL4
 | | Crystal structure of Coh-OlpA(Cthe_3080)-Doc918(Cthe_0918) complex: A novel type I Cohesin-Dockerin complex from Clostridium thermocellum ATTC 27405 | | Descriptor: | CALCIUM ION, Cellulosome enzyme, dockerin type I, ... | | Authors: | Alves, V.D, Carvalho, A.L, Najmudin, S.H, Bras, J, Prates, J.A.M, Fontes, C.M.G.A. | | Deposit date: | 2011-11-10 | | Release date: | 2012-11-28 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Novel Clostridium thermocellum Type I Cohesin-Dockerin Complexes Reveal a Single Binding Mode.
J.Biol.Chem., 287, 2012
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5K39
 | | THE TYPE II COHESIN DOCKERIN COMPLEX FROM CLOSTRIDIUM THERMOCELLUM | | Descriptor: | CALCIUM ION, Cellulosome anchoring protein cohesin region, Dockerin module from a protein of unknown function | | Authors: | Viegas, A, Pinheiro, B, Bras, J.L.A, Romao, M.J, Alves, V, Carvalho, A.L, Fontes, C.M.G.A. | | Deposit date: | 2016-05-19 | | Release date: | 2017-03-29 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Diverse specificity of cellulosome attachment to the bacterial cell surface.
Sci Rep, 6, 2016
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5M2O
 | | R. flavefaciens' third ScaB cohesin in complex with a group 1 dockerin | | Descriptor: | CALCIUM ION, Group I Dockerin, Putative cellulosomal scaffoldin protein | | Authors: | Bule, P, Najmudin, S, Carvalho, A.L, Fontes, C.M.G.A. | | Deposit date: | 2016-10-13 | | Release date: | 2017-07-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes.
Sci Rep, 7, 2017
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5LU3
 | | The Structure of Spirochaeta thermophila CBM64 | | Descriptor: | 3,6,9,12,15-pentaoxaoctadecan-17-amine, 4-oxobutanoic acid, CALCIUM ION, ... | | Authors: | Correia, M.A.S, Romao, M.J, Carvalho, A.L. | | Deposit date: | 2016-09-07 | | Release date: | 2017-02-15 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Stability and Ligand Promiscuity of Type A Carbohydrate-binding Modules Are Illustrated by the Structure of Spirochaeta thermophila StCBM64C.
J. Biol. Chem., 292, 2017
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5M2S
 | | R. flavefaciens' third ScaB cohesin in complex with a group 1 dockerin | | Descriptor: | CALCIUM ION, Doc8: Type I dockerin repeat domain from family 9 glycoside hydrolase WP_009982745[Ruminococcus flavefaciens], GLYCEROL, ... | | Authors: | Bule, P, Najmudin, S, Carvalho, A.L, Fontes, C.M.G.A. | | Deposit date: | 2016-10-13 | | Release date: | 2017-07-05 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes.
Sci Rep, 7, 2017
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5M0Y
 | | Crystal Structure of the CohScaA-XDocCipB type II complex from Clostridium thermocellum at 1.5Angstrom resolution | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cellulosome anchoring protein cohesin region, ... | | Authors: | Pinheiro, B.A, Bras, J.L, Carvalho, A.L, Fontes, C.M.G.A. | | Deposit date: | 2016-10-06 | | Release date: | 2017-09-06 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Diverse specificity of cellulosome attachment to the bacterial cell surface.
Sci Rep, 6, 2016
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2Y3N
 | | Type II cohesin-dockerin domain from Bacteroides cellolosolvens | | Descriptor: | CALCIUM ION, CELLULOSOMAL FAMILY-48 PROCESSIVE GLYCOSIDE HYDROLASE, CELLULOSOMAL SCAFFOLDIN | | Authors: | Viegas, A, Carvalho, A.L, Romao, M.J, Prates, J.A.M, Fontes, C.M.G.A. | | Deposit date: | 2010-12-22 | | Release date: | 2012-01-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Type II Cohesin-Dockerin Domain from Bacteroides Cellolosolvens
To be Published
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4AYZ
 | | X-ray Structure of human SOUL | | Descriptor: | HEME-BINDING PROTEIN 2 | | Authors: | Freire, F, Carvalho, A.L, Aveiro, S.S, Charbonnier, P, Moulis, J.M, Romao, M.J, Goodfellow, B.J, Macedo, A.L. | | Deposit date: | 2012-06-22 | | Release date: | 2012-07-11 | | Last modified: | 2024-11-06 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Human Soul: A Heme-Binding or a Bh3 Domain-Containing Protein
To be Published
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4B0Y
 | | Determination of X-ray Structure of human SOUL by Molecular Replacement | | Descriptor: | HEME-BINDING PROTEIN 2 | | Authors: | Freire, F, Carvalho, A.L, Aveiro, S.S, Charbonnier, P, Moulis, J.M, Romao, M.J, Goodfellow, B.J, Macedo, A.L. | | Deposit date: | 2012-07-06 | | Release date: | 2012-08-01 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Human Soul: A Heme-Binding or a Bh3 Domain-Containing Protein
To be Published
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1CFW
 | | GA-SUBSTITUTED DESULFOREDOXIN | | Descriptor: | GALLIUM (III) ION, PROTEIN (DESULFOREDOXIN), SULFATE ION | | Authors: | Archer, M, Carvalho, A.L, Teixeira, S, Moura, I, Moura, J.J.G, Rusnak, F, Romao, M.J. | | Deposit date: | 1999-03-22 | | Release date: | 1999-07-09 | | Last modified: | 2024-12-25 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural studies by X-ray diffraction on metal substituted desulforedoxin, a rubredoxin-type protein.
Protein Sci., 8, 1999
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1DCD
 | | DESULFOREDOXIN COMPLEXED WITH CD2+ | | Descriptor: | CADMIUM ION, PROTEIN (DESULFOREDOXIN) | | Authors: | Archer, M, Carvalho, A.L, Teixeira, S, Romao, M.J. | | Deposit date: | 1999-03-20 | | Release date: | 1999-07-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural studies by X-ray diffraction on metal substituted desulforedoxin, a rubredoxin-type protein.
Protein Sci., 8, 1999
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1DHG
 | | HG-SUBSTITUTED DESULFOREDOXIN | | Descriptor: | MERCURY (II) ION, PROTEIN (DESULFOREDOXIN) | | Authors: | Archer, M, Carvalho, A.L, Teixeira, S, Moura, I, Moura, J.J.G, Rusnak, F, Romao, M.J. | | Deposit date: | 1999-03-22 | | Release date: | 1999-07-09 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural studies by X-ray diffraction on metal substituted desulforedoxin, a rubredoxin-type protein.
Protein Sci., 8, 1999
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1SPP
 | | THE CRYSTAL STRUCTURES OF TWO MEMBERS OF THE SPERMADHESIN FAMILY REVEAL THE FOLDING OF THE CUB DOMAIN | | Descriptor: | MAJOR SEMINAL PLASMA GLYCOPROTEIN PSP-I, MAJOR SEMINAL PLASMA GLYCOPROTEIN PSP-II | | Authors: | Romero, A, Romao, M.J, Varela, P.F, Kolln, I, Dias, J.M, Carvalho, A.L, Sanz, L, Topfer-Petersen, E, Calvete, J.J. | | Deposit date: | 1997-06-19 | | Release date: | 1998-06-24 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structures of two spermadhesins reveal the CUB domain fold.
Nat.Struct.Biol., 4, 1997
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1SFP
 | | CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY | | Descriptor: | ASFP | | Authors: | Romao, M.J, Kolln, I, Dias, J.M, Carvalho, A.L, Romero, A, Varela, P.F, Sanz, L, Topfer-Petersen, E, Calvete, J.J. | | Deposit date: | 1997-06-24 | | Release date: | 1998-06-24 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The crystal structures of two spermadhesins reveal the CUB domain fold.
Nat.Struct.Biol., 4, 1997
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4AO1
 | | High resolution crystal structure of bovine pancreatic ribonuclease crystallized using ionic liquid | | Descriptor: | CHLORIDE ION, RIBONUCLEASE PANCREATIC, SULFATE ION | | Authors: | Mukhopadhyay, A, Carvalho, A.L, Kowacz, M, Romao, M.J. | | Deposit date: | 2012-03-23 | | Release date: | 2012-07-18 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | Hofmeister Effects of Ionic Liquids in Protein Crystallization: Direct and Water-Mediated Interactions
Cryst.Eng.Comm., 14, 2012
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4AGA
 | | Hofmeister effects of ionic liquids in protein crystallization: direct and water-mediated interactions | | Descriptor: | ACETATE ION, CHLORIDE ION, CHOLINE ION, ... | | Authors: | Mukhopadhyay, A, Carvalho, A.L, Romao, M.J. | | Deposit date: | 2012-01-25 | | Release date: | 2012-07-18 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Hofmeister Effects of Ionic Liquids in Protein Crystallization: Direct and Water-Mediated Interactions
Cryst.Eng.Comm., 14, 2012
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2LRO
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