1SPP

THE CRYSTAL STRUCTURES OF TWO MEMBERS OF THE SPERMADHESIN FAMILY REVEAL THE FOLDING OF THE CUB DOMAIN

Summary for 1SPP

Entry DOI	10.2210/pdb1spp/pdb
Descriptor	MAJOR SEMINAL PLASMA GLYCOPROTEIN PSP-I, MAJOR SEMINAL PLASMA GLYCOPROTEIN PSP-II (3 entities in total)
Functional Keywords	seminal plasma proteins, spermadhesins, cub domain architecture, complex (seminal plasma protein-spp), complex (seminal plasma protein-spp) complex, complex (seminal plasma protein/spp)
Biological source	Sus scrofa (pig) More
Cellular location	Secreted: P35495 P35496
Total number of polymer chains	2
Total formula weight	24656.11
Authors	Romero, A.,Romao, M.J.,Varela, P.F.,Kolln, I.,Dias, J.M.,Carvalho, A.L.,Sanz, L.,Topfer-Petersen, E.,Calvete, J.J. (deposition date: 1997-06-19, release date: 1998-06-24, Last modification date: 2024-10-16)
Primary citation	Romero, A.,Romao, M.J.,Varela, P.F.,Kolln, I.,Dias, J.M.,Carvalho, A.L.,Sanz, L.,Topfer-Petersen, E.,Calvete, J.J. The crystal structures of two spermadhesins reveal the CUB domain fold. Nat.Struct.Biol., 4:783-788, 1997 Cited by PubMed Abstract: Spermadhesins, 12,000-14,000 M(r) mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 A and 1.9 A resolution respectively. PubMed: 9334740 DOI: 10.1038/nsb1097-783 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation