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4Z16
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BU of 4z16 by Molmil
Crystal Structure of the Jak3 Kinase Domain Covalently Bound to N-(3-(((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)methyl)phenyl)acrylamide
Descriptor: N-(3-{[(5-chloro-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)amino]methyl}phenyl)prop-2-enamide, Tyrosine-protein kinase JAK3
Authors:McNally, R, Tan, L, Gray, N.S, Eck, M.J.
Deposit date:2015-03-26
Release date:2016-02-10
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Development of Selective Covalent Janus Kinase 3 Inhibitors.
J.Med.Chem., 58, 2015
4X67
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BU of 4x67 by Molmil
Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions.
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, L, Chong, J, Wang, D.
Deposit date:2014-12-07
Release date:2015-02-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X6A
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BU of 4x6a by Molmil
Crystal structure of yeast RNA polymerase II encountering oxidative Cyclopurine DNA lesions
Descriptor: DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ...
Authors:Wang, L, Chong, J, Wang, D.
Deposit date:2014-12-07
Release date:2015-02-04
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.96 Å)
Cite:Mechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
Proc.Natl.Acad.Sci.USA, 112, 2015
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數據於2024-07-24公開中

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