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7LV6
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BU of 7lv6 by Molmil
The structure of MalL mutant enzyme S536R from Bacillus subtilis
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ...
Authors:Hamill, C.J, Prentice, E.J, Bahl, C.D, Truebridge, I.S, Arcus, V.L.
Deposit date:2021-02-24
Release date:2022-03-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Urea binding to guide rational design of mutations that influence enzyme dynamics
To Be Published
6NSN
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BU of 6nsn by Molmil
TetR family transcriptional regulator CifR C99T-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Descriptor: DNA (26-MER), GLYCEROL, TetR family transcriptional regulator CifR
Authors:He, S, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024
6NSM
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BU of 6nsm by Molmil
TetR family transcriptional regulator CifR C99T-C107S-C181R Cysteines mutant complexed with 26bp double-strand operator DNA
Descriptor: DNA (26-MER), TetR family transcriptional regulator CifR
Authors:He, S, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024
6NSR
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BU of 6nsr by Molmil
TetR family transcriptional regulator CifR C99T-C181R cysteine mutant complexed with 26bp double-strand operator DNA and apo-CifR C99T-C181R
Descriptor: CifR, DNA (26-MER)
Authors:He, S, Taher, N.M, Simard, A.R, Madden, D.R.
Deposit date:2019-01-25
Release date:2020-01-29
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (3 Å)
Cite:Molecular basis for the transcriptional regulation of an epoxide-based virulence circuit in Pseudomonas aeruginosa
Biorxiv, 2024
8GIJ
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BU of 8gij by Molmil
TEM-1 Beta Lactamase Variant 80.b
Descriptor: TEM-1 Beta Lactmase Variant 80.b
Authors:Fram, B.F, Gauthier, N.P, Khan, A, Sander, C.
Deposit date:2023-03-14
Release date:2024-04-17
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Nat Commun, 15, 2024
8GII
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BU of 8gii by Molmil
TEM-1 Beta Lactamase Variant 80.a
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, TEM-1 Variant 80.a
Authors:Fram, B.F, Gauthier, N.P, Khan, A.R, Sander, C.
Deposit date:2023-03-14
Release date:2024-04-17
Last modified:2024-07-17
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Simultaneous enhancement of multiple functional properties using evolution-informed protein design.
Nat Commun, 15, 2024
6X1X
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BU of 6x1x by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC)
Descriptor: GLYCEROL, mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X23
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BU of 6x23 by Molmil
PDZ domain from choanoflagellate SHANK1 (mbSHANK1) bound to GIRK3 peptide
Descriptor: G protein-activated inward rectifier potassium channel 3, mbSHANK1 protein
Authors:Gao, M, Mackley, I.G.P, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.154 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1R
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BU of 6x1r by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ2 (mbDLG-2) in spacegroup P212121
Descriptor: GLYCEROL, mbDLG protein
Authors:Bamonte, H.A, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1P
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BU of 6x1p by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ2 (mbDLG-2) in spacegroup I2
Descriptor: mbDLG protein
Authors:Bamonte, H.A, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1N
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BU of 6x1n by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ3 (mbDLG-3)
Descriptor: GLYCEROL, mbDLG-3 protein
Authors:Mackley, I, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X20
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BU of 6x20 by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC) bound to B1AR peptide
Descriptor: mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X22
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BU of 6x22 by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC) bound to GAIP peptide
Descriptor: mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
4E35
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BU of 4e35 by Molmil
Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL50 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
4E34
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BU of 4e34 by Molmil
Crystal structure of CFTR Associated Ligand (CAL) PDZ domain bound to iCAL36 (ANSRWPTSII) peptide
Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, decameric peptide, ...
Authors:Amacher, J.F, Beck, T, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.395 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
4E3B
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BU of 4e3b by Molmil
Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Descriptor: Tax1-binding protein 3, iCAL50 peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2012-03-09
Release date:2012-12-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP.
J.Biol.Chem., 288, 2013
5TNK
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BU of 5tnk by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 1,2-Epoxyoctane hydrolysis intermediate
Descriptor: (2R)-octane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNL
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BU of 5tnl by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (S)-1,2-Epoxyhexane hydrolysis intermediate
Descriptor: (2R)-hexane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TND
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BU of 5tnd by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 1,2-Epoxycyclohexane hydrolysis intermediate
Descriptor: (1R,2R)-cyclohexane-1,2-diol, (1S,2S)-cyclohexane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNH
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BU of 5tnh by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 17,18-EpETE hydrolysis intermediate
Descriptor: (5Z,8Z,11Z,14Z,17R,18R)-17,18-dihydroxyicosa-5,8,11,14-tetraenoic acid, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNS
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BU of 5tns by Molmil
Crystal structure of the D129S mutant of the CFTR inhibitory factor Cif containing 1,2-Epoxycyclohexane
Descriptor: (1R,6S)-7-oxabicyclo[4.1.0]heptane, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNF
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BU of 5tnf by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 19,20-EpDPE hydrolysis intermediate
Descriptor: (4Z,7Z,10Z,13Z,16Z,19R,20R)-19,20-dihydroxydocosa-4,7,10,13,16-pentaenoic acid, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNQ
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BU of 5tnq by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (R)-Styrene oxide hydrolysis intermediate
Descriptor: (1R)-1-phenylethane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNJ
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BU of 5tnj by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 4-Vinyl-1-cyclohexene 1,2-epoxide hydrolysis intermediate
Descriptor: (1R,2R,4R)-4-ethenylcyclohexane-1,2-diol, (1R,2R,4S)-4-ethenylcyclohexane-1,2-diol, (1S,2S,4R)-4-ethenylcyclohexane-1,2-diol, ...
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017
5TNN
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BU of 5tnn by Molmil
Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted (S)-1,2-Epoxyoctane hydrolysis intermediate
Descriptor: (2R)-octane-1,2-diol, CFTR inhibitory factor
Authors:Hvorecny, K.L, Madden, D.R.
Deposit date:2016-10-14
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Active-Site Flexibility and Substrate Specificity in a Bacterial Virulence Factor: Crystallographic Snapshots of an Epoxide Hydrolase.
Structure, 25, 2017

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數據於2024-09-11公開中

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