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4Q6H
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BU of 4q6h by Molmil
CFTR Associated Ligand (CAL) bound to last 6 residues of CFTR (decameric peptide: iCAL36VQDTRL)
Descriptor: CFTR-associated ligand, SULFITE ION, iCAL36-VQDTRL peptide
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2014-04-22
Release date:2014-05-14
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Understanding PDZ Affinity and Selectivity: All Residues Considered
TO BE PUBLISHED
4QAO
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BU of 4qao by Molmil
Lysine-ligated cytochrome c with F82H
Descriptor: Cytochrome c iso-1, PROTOPORPHYRIN IX CONTAINING FE
Authors:Amacher, J.F, Zhu, M.Q, Zhong, F, Pletneva, E.K, Madden, D.R.
Deposit date:2014-05-05
Release date:2015-08-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Understanding PDZ Affinity and Selectivity: All Residues Considered
Thesis, 2014
4Q6S
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BU of 4q6s by Molmil
CFTR Associated Ligand (CAL) PDZ bound to biotinylated peptide BT-L-iCAL36
Descriptor: BT-L-iCAL36 peptide, Golgi-associated PDZ and coiled-coil motif-containing protein
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2014-04-23
Release date:2015-04-29
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Modulator Preferences are Critical Co-Determinants of PDZ Network Wiring
To be Published
3SFJ
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BU of 3sfj by Molmil
Crystal Structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36 inhibitor peptide
Descriptor: Tax1-binding protein 3, decameric peptide iCAL36
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2011-06-13
Release date:2012-12-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published
4NNL
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BU of 4nnl by Molmil
Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide
Descriptor: TIP-1 PDZ domain, Tax1-binding protein 3
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-11-18
Release date:2015-01-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published
4NNM
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BU of 4nnm by Molmil
Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to Y-iCAL36 (YPTSII) peptide
Descriptor: GLYCEROL, TIP-1 PDZ domain, Tax1-binding protein 3
Authors:Amacher, J.F, Madden, D.R.
Deposit date:2013-11-18
Release date:2015-01-21
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR
To be Published
7S51
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BU of 7s51 by Molmil
Structure of C208A Sortase A from Streptococcus pyogenes bound to LPATA peptide
Descriptor: LEU-PRO-ALA-THR-ALA, Sortase
Authors:Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F.
Deposit date:2021-09-09
Release date:2022-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
7S4O
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BU of 7s4o by Molmil
Structure of C208A Sortase A from Streptococcus pyogenes bound to LPATS peptide
Descriptor: LEU-PRO-ALA-THR-SER-GLY, Sortase
Authors:Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F.
Deposit date:2021-09-09
Release date:2022-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.396 Å)
Cite:Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
8SNQ
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BU of 8snq by Molmil
Streptococcus pyogenes Sortase A (SrtA) with the F145E mutation
Descriptor: Sortase
Authors:Kodama, H.M, Amacher, J.F.
Deposit date:2023-04-27
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Streptococcus pyogenes Sortase A (SrtA) with the F145E mutation
To Be Published
8T8G
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BU of 8t8g by Molmil
C208A Streptococcus pyogenes Sortase A (spySrtA) bound to LPALA peptide
Descriptor: LEU-PRO-ALA-LEU-ALA-GLY, Sortase
Authors:Kodama, H.M, Amacher, J.F.
Deposit date:2023-06-22
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A unique binding mode of P1' Leu-containing target sequences for Streptococcus pyogenes sortase A results in alternative cleavage.
Rsc Chem Biol, 5, 2024
7T8Y
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BU of 7t8y by Molmil
Structure of Class A sortase from Streptococcus pyogenes bound to lipid II mimetic, LPATA: Thr-in conformation
Descriptor: ACE-ALA-ZGL-LYS-DAL-DAL, BE2-LEU-PRO-ALA-THR-ALA-ALA, Sortase
Authors:Piper, I.M, Antos, J.M, Amacher, J.F.
Deposit date:2021-12-17
Release date:2022-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
7T8Z
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BU of 7t8z by Molmil
Structure of Class A sortase from Streptococcus pyogenes bound to lipid II mimetic, LPATA: Thr-out conformation
Descriptor: ACE-ALA-ZGL-LYS-DAL-DAL, BE2-LEU-PRO-ALA-THR-ALA-ALA, Sortase
Authors:Piper, I.M, Antos, J.M, Amacher, J.F.
Deposit date:2021-12-17
Release date:2022-09-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition.
J.Biol.Chem., 298, 2022
6X1N
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BU of 6x1n by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ3 (mbDLG-3)
Descriptor: GLYCEROL, mbDLG-3 protein
Authors:Mackley, I, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X20
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BU of 6x20 by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC) bound to B1AR peptide
Descriptor: mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1X
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BU of 6x1x by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC)
Descriptor: GLYCEROL, mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.198 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1P
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BU of 6x1p by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ2 (mbDLG-2) in spacegroup I2
Descriptor: mbDLG protein
Authors:Bamonte, H.A, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X23
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BU of 6x23 by Molmil
PDZ domain from choanoflagellate SHANK1 (mbSHANK1) bound to GIRK3 peptide
Descriptor: G protein-activated inward rectifier potassium channel 3, mbSHANK1 protein
Authors:Gao, M, Mackley, I.G.P, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.154 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X1R
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BU of 6x1r by Molmil
Crystal Structure of Choanoflagellate (Monosiga brevicollis) Dlg1 PDZ2 (mbDLG-2) in spacegroup P212121
Descriptor: GLYCEROL, mbDLG protein
Authors:Bamonte, H.A, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
6X22
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BU of 6x22 by Molmil
PDZ domain from choanoflagellate GIPC (mbGIPC) bound to GAIP peptide
Descriptor: mbGIPC protein
Authors:Gao, M, Amacher, J.F.
Deposit date:2020-05-19
Release date:2020-11-25
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structural characterization and computational analysis of PDZ domains in Monosiga brevicollis.
Protein Sci., 29, 2020
7S56
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BU of 7s56 by Molmil
Sortase A from Streptococcus agalactiae, residues 79-247
Descriptor: Class A sortase
Authors:Gao, M, Kodama, H.M, Antos, J.M, Amacher, J.F.
Deposit date:2021-09-09
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes.
Protein Sci., 31, 2022
7S54
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BU of 7s54 by Molmil
Sortase A from Streptococcus agalactiae with the deltaN188 b7-b8 loop sequence from Staphylococcus aureus Sortase A
Descriptor: Class A sortase, sortase A chimera
Authors:Gao, M, Kodama, H.M, Antos, J.M, Amacher, J.F.
Deposit date:2021-09-09
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.794 Å)
Cite:Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes.
Protein Sci., 31, 2022
7S57
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BU of 7s57 by Molmil
Structure of Sortase A from Streptococcus pyogenes with the b7-b8 loop sequence of Enterococcus faecalis Sortase A
Descriptor: Class A sortase, sortase A chimera
Authors:Svendsen, J.E, Johnson, D.A, Gao, M, Antos, J.M, Amacher, J.F.
Deposit date:2021-09-09
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes.
Protein Sci., 31, 2022
7S53
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BU of 7s53 by Molmil
Structure of Sortase A from Streptococcus pyogenes with the b7-b8 loop sequence from Listeria monocytogenes Sortase A
Descriptor: Class A sortase, sortase A chimera
Authors:Johnson, D.A, Svendsen, J.E, Antos, J.M, Amacher, J.F.
Deposit date:2021-09-09
Release date:2022-01-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural and biochemical analyses of selectivity determinants in chimeric Streptococcus Class A sortase enzymes.
Protein Sci., 31, 2022
4DLN
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BU of 4dln by Molmil
Crystal structure of the CFTR inhibitory factor Cif with the D129S mutation
Descriptor: Putative hydrolase
Authors:Bahl, C.D, Amacher, J.F, Madden, D.R.
Deposit date:2012-02-06
Release date:2013-08-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Inhibiting an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa Protects CFTR.
Angew.Chem.Int.Ed.Engl., 54, 2015
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數據於2024-11-06公開中

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