2JM2
| Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs | Descriptor: | Insulin-like growth factor-binding protein 6 | Authors: | Chandrashekaran, I.R, Yao, S, Wang, C.C, Bansal, P.S, Alewood, P.F, Forbes, B.E, Wallace, J.C, Bach, L.A, Norton, R.S. | Deposit date: | 2006-09-18 | Release date: | 2007-03-27 | Last modified: | 2023-12-20 | Method: | SOLUTION NMR | Cite: | The N-Terminal Subdomain of Insulin-like Growth Factor (IGF) Binding Protein 6. Structure and Interaction with IGFs Biochemistry, 46, 2007
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2KYJ
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1D4L
| HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR | Descriptor: | (10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENESULFONYL-1''-AMINO-3''-METHYLBUTYL)ETHYL]-8,11-DIOXO-10-ISOPROPYL-2-OXA-9,12-DIAZABICYCLO [13.2.2]NONADECA-15,17,18-TRIENE, HIV-1 PROTEASE, SULFATE ION | Authors: | Tyndall, J.D, Reid, R.C, Tyssen, D.P, Jardine, D.K, Todd, B, Passmore, M, March, D.R, Pattenden, L.K, Alewood, D, Hu, S.H, Alewood, P.F, Birch, C.J, Martin, J.L, Fairlie, D.P. | Deposit date: | 1999-10-04 | Release date: | 2000-10-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. J.Med.Chem., 43, 2000
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1D4K
| HIV-1 PROTEASE COMPLEXED WITH A MACROCYCLIC PEPTIDOMIMETIC INHIBITOR | Descriptor: | HIV-1 PROTEASE, N-13-[(10S,13S)-9,12-DIOXO-10-(2-BUTYL)-2-OXA-8,11-DIAZABICYCLO [13.2.2] NONADECA-15,17,18-TRIENE] (2R)-BENZYL-(4S)-HYDROXY-5-AMINOPENTANOIC (1R)-HYDROXY-(2S)-INDANEAMIDE, SULFATE ION | Authors: | Tyndall, J.D, Reid, R.C, Tyssen, D.P, Jardine, D.K, Todd, B, Passmore, M, March, D.R, Pattenden, L.K, Alewood, D, Hu, S.H, Alewood, P.F, Birch, C.J, Martin, J.L, Fairlie, D.P. | Deposit date: | 1999-10-04 | Release date: | 2000-10-11 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Synthesis, stability, antiviral activity, and protease-bound structures of substrate-mimicking constrained macrocyclic inhibitors of HIV-1 protease. J.Med.Chem., 43, 2000
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1IEN
| SOLUTION STRUCTURE OF TIA | Descriptor: | PROTEIN TIA | Authors: | Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J. | Deposit date: | 2001-04-10 | Release date: | 2002-04-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat.Neurosci., 4, 2001
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1IEO
| SOLUTION STRUCTURE OF MRIB-NH2 | Descriptor: | PROTEIN MRIB-NH2 | Authors: | Sharpe, I.A, Gehrmann, J, Loughnan, M.L, Thomas, L, Adams, D.A, Atkins, A, Palant, E, Craik, D.J, Adams, D.J, Alewood, P.F, Lewis, R.J. | Deposit date: | 2001-04-10 | Release date: | 2002-04-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Two new classes of conopeptides inhibit the alpha1-adrenoceptor and noradrenaline transporter. Nat.Neurosci., 4, 2001
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1XGB
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1XGC
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1XGA
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1KQH
| NMR Solution Structure of the cis Pro30 Isomer of ACTX-Hi:OB4219 | Descriptor: | ACTX-Hi:OB4219 | Authors: | Rosengren, K.J, Wilson, D, Daly, N.L, Alewood, P.F, Craik, D.J. | Deposit date: | 2002-01-05 | Release date: | 2002-02-06 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin
from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within
its four disulfide bonds Biochemistry, 41, 2002
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1KQI
| NMR Solution Structure of the trans Pro30 Isomer of ACTX-Hi:OB4219 | Descriptor: | ACTX-Hi:OB4219 | Authors: | Rosengren, K.J, Wilson, D, Daly, N.L, Alewood, P.F, Craik, D.J. | Deposit date: | 2002-01-06 | Release date: | 2002-02-06 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structures of the cis- and trans-Pro30 isomers of a novel 38-residue toxin
from the venom of Hadronyche Infensa sp. that contains a cystine-knot motif within
its four disulfide bonds Biochemistry, 41, 2002
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1ZUF
| Solution Structure of DLP-4 | Descriptor: | Defensin-like peptide 2/4 | Authors: | Torres, A.M, Tsampazi, C, Geraghty, D.P, Bansal, P.S, Alewood, P.F, Kuchel, P.W. | Deposit date: | 2005-05-31 | Release date: | 2005-08-02 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties. Biochem.J., 391, 2005
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1ZUE
| Revised Solution Structure of DLP-2 | Descriptor: | Defensin-like peptide 2/4 | Authors: | Torres, A.M, Tsampazi, C, Geraghty, D.P, Bansal, P.S, Alewood, P.F, Kuchel, P.W. | Deposit date: | 2005-05-30 | Release date: | 2005-08-02 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties. Biochem.J., 391, 2005
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1MII
| SOLUTION STRUCTURE OF ALPHA-CONOTOXIN MII | Descriptor: | PROTEIN (ALPHA CONOTOXIN MII) | Authors: | Hill, J.M, Oomen, C.J, Miranda, L.P, Bingham, J.P, Alewood, P.F, Craik, D.J. | Deposit date: | 1998-10-05 | Release date: | 1998-10-21 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of alpha-conotoxin MII by NMR spectroscopy: effects of solution environment on helicity. Biochemistry, 37, 1998
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1PEN
| ALPHA-CONOTOXIN PNI1 | Descriptor: | ALPHA-CONOTOXIN PNIA | Authors: | Hu, S.-H, Gehrmann, J, Guddat, L.W, Alewood, P.F, Craik, D.J, Martin, J.L. | Deposit date: | 1996-01-29 | Release date: | 1997-04-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | The 1.1 A crystal structure of the neuronal acetylcholine receptor antagonist, alpha-conotoxin PnIA from Conus pennaceus. Structure, 4, 1996
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1EYO
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1B6P
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 7 | Descriptor: | N-[3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YAMINO)-2-HYDROXY-1-(4-HYDROXY-BENZYL) -PROPYL]-3-METHYL-2-PROPIONYLAMINO-BUTYRAMIDE, RETROPEPSIN, SULFATE ION | Authors: | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | Deposit date: | 1999-01-17 | Release date: | 2000-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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2NS3
| Solution structure of ribbon BuIA | Descriptor: | Alpha-conotoxin BuIA | Authors: | Jin, A.H, Brandstaetter, H, Nevin, S.T, Tan, C.C, Clark, R.J, Adams, D.J, Alewood, P.F, Craik, D.J, Daly, N.L. | Deposit date: | 2006-11-03 | Release date: | 2007-09-25 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics Bmc Struct.Biol., 7, 2007
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1B6M
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 6 | Descriptor: | RETROPEPSIN, SULFATE ION, [1-BENZYL-3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2] HEPTADECA-1(16),13(17),14-TRIEN-11-YLAMINO)-2-HYDROXY-PROPYL]-CARBAMIC ACID TERT-BUTYL ESTER | Authors: | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | Deposit date: | 1999-01-17 | Release date: | 2000-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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1B6J
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 1 | Descriptor: | CYCLIC PEPTIDE INHIBITOR, RETROPEPSIN, SULFATE ION | Authors: | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | Deposit date: | 1999-01-17 | Release date: | 2000-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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1B6K
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 5 | Descriptor: | N-[3-(8-SEC-BUTYL-7,10-DIOXO-2-OXA-6,9-DIAZA-BICYCLO[11.2.2]HEPTADECA-1(16),13(17),14- TRIEN-11-YLAMINO)-2-HYDROXY-1-(4-HYDROXY-BENZYL)-PROPYL]-3-METHYL-2- (2-OXO-PYRROLIDIN-1-YL)-BUTYRAMIDE, RETROPEPSIN, SULFATE ION | Authors: | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | Deposit date: | 1999-01-17 | Release date: | 2000-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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1B6L
| HIV-1 PROTEASE COMPLEXED WITH MACROCYCLIC PEPTIDOMIMETIC INHIBITOR 4 | Descriptor: | 1-[2-(8-CARBAMOYLMETHYL-6,9-DIOXO-2-OXA-7,10-DIAZA-BICYCLO[11.2.2]HEPTADECA- 1(16),13(17),14-TRIEN-11-YL)-2-HYDROXY-ETHYL]-PIPERIDINE-2-CARBOXYLIC ACID TERT-BUTYLAMIDE, RETROPEPSIN, SULFATE ION | Authors: | Martin, J.L, Begun, J, Schindeler, A, Wickramasinghe, W.A, Alewood, D, Alewood, P.F, Bergman, D.A, Brinkworth, R.I, Abbenante, G, March, D.R, Reid, R.C, Fairlie, D.P. | Deposit date: | 1999-01-17 | Release date: | 2000-01-07 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease. Biochemistry, 38, 1999
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1B8W
| DEFENSIN-LIKE PEPTIDE 1 | Descriptor: | PROTEIN (DEFENSIN-LIKE PEPTIDE 1) | Authors: | Torres, A.M, Wang, X, Fletcher, J.I, Alewood, D, Alewood, P.F, Smith, R, Simpson, R.J, Nicholson, G.M, Sutherland, S.K, Gallagher, C.H, King, G.F, Kuchel, P.W. | Deposit date: | 1999-02-02 | Release date: | 1999-09-15 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a defensin-like peptide from platypus venom. Biochem.J., 341, 1999
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2MFA
| Mambalgin-2 | Descriptor: | Mambalgin-2 | Authors: | Schroeder, C.I, Rash, L.D, Vila-Farres, X, Rosengren, K.J, Mobli, M, King, G.F, Alewood, P.F, Craik, D.J, Durek, T. | Deposit date: | 2013-10-08 | Release date: | 2014-01-01 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin-2. Angew.Chem.Int.Ed.Engl., 53, 2014
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1AG7
| CONOTOXIN GS, NMR, 20 STRUCTURES | Descriptor: | CONOTOXIN GS | Authors: | Hill, J.M, Alewood, P.F, Craik, D.J. | Deposit date: | 1997-04-03 | Release date: | 1998-04-08 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structure of the sodium channel antagonist conotoxin GS: a new molecular caliper for probing sodium channel geometry. Structure, 5, 1997
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