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1UQR
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BU of 1uqr by Molmil
Type II 3-dehydroquinate dehydratase (DHQase) from Actinobacillus pleuropneumoniae
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-DEHYDROQUINATE DEHYDRATASE, SULFATE ION
Authors:Maes, D, Gonzalez-Ramirez, L.A, Lopez-Jaramillo, J, Yu, B, De Bondt, H, Zegers, I, Afonina, E, Garcia-Ruiz, J.M, Gulnik, S.
Deposit date:2003-10-16
Release date:2003-10-30
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural Study of the Type II 3-Dehydroquinate Dehydratase from Actinobacillus Pleuropneumoniae
Acta Crystallogr.,Sect.D, 60, 2004
2HBQ
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BU of 2hbq by Molmil
Crystal structure of wildtype human caspase-1 in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-06-14
Release date:2006-06-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Common Allosteric Site and Mechanism in Caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2GMR
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BU of 2gmr by Molmil
Photosynthetic reaction center mutant from Rhodobacter sphaeroides with Asp L210 replaced with Asn
Descriptor: BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, FE (II) ION, ...
Authors:Stachnik, J.M, Hermes, S, Gerwert, K, Hofmann, E.
Deposit date:2006-04-07
Release date:2006-11-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Proton uptake in the reaction center mutant L210DN from Rhodobacter sphaeroides via protonated water molecules.
Biochemistry, 45, 2006
1UNV
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BU of 1unv by Molmil
Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
Descriptor: GENERAL CONTROL PROTEIN GCN4
Authors:Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
Deposit date:2003-09-15
Release date:2004-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
1UQW
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BU of 1uqw by Molmil
Crystal structure of yliB protein from escherichia coi
Descriptor: GLYCEROL, PUTATIVE BINDING PROTEIN YLIB, ZINC ION
Authors:Jeudy, S, Abergel, C, Claverie, J.M.
Deposit date:2003-10-22
Release date:2003-10-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Crystal Structure of Ylib Protein from E.Coli
To be Published
2GZV
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BU of 2gzv by Molmil
The cystal structure of the PDZ domain of human PICK1
Descriptor: PRKCA-binding protein
Authors:Debreczeni, J.E, Elkins, J.M, Yang, X, Berridge, G, Bray, J, Colebrook, S, Smee, C, Savitsky, P, Gileadi, O, Turnbull, A, von Delft, F, Doyle, D.A, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC)
Deposit date:2006-05-12
Release date:2006-07-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
1UVK
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BU of 1uvk by Molmil
The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex
Descriptor: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
Deposit date:2004-01-21
Release date:2004-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
2GU8
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BU of 2gu8 by Molmil
Discovery of 2-Pyrimidyl-5-Amidothiophenes as Novel and Potent Inhibitors for AKT: Synthesis and SAR Studies
Descriptor: CAMP-dependent protein kinase, alpha-catalytic subunit, N-[(1S)-2-AMINO-1-(2,4-DICHLOROBENZYL)ETHYL]-5-[2-(METHYLAMINO)PYRIMIDIN-4-YL]THIOPHENE-2-CARBOXAMIDE, ...
Authors:Murray, J.M.
Deposit date:2006-04-28
Release date:2007-05-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of 2-pyrimidyl-5-amidothiophenes as potent inhibitors for AKT: synthesis and SAR studies
Bioorg.Med.Chem.Lett., 16, 2006
1D6H
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BU of 1d6h by Molmil
CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA)
Descriptor: CHALCONE SYNTHASE, COENZYME A, SULFATE ION
Authors:Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P.
Deposit date:1999-10-13
Release date:2000-02-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
2H48
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BU of 2h48 by Molmil
Crystal structure of human caspase-1 (Cys362->Ala, Cys364->Ala, Cys397->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase 1, isoform gamma, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-05-23
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A common allosteric site and mechanism in caspases
Proc.Natl.Acad.Sci.USA, 103, 2006
2H54
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BU of 2h54 by Molmil
Crystal structure of human caspase-1 (Thr388->Ala) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-05-25
Release date:2008-03-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
2H72
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BU of 2h72 by Molmil
Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
Authors:Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2006-06-01
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal Structure of Thioredoxin mutant E85D in Hexagonal (p61) Space Group
To be Published
2GL0
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BU of 2gl0 by Molmil
Structure of PAE2307 in complex with adenosine
Descriptor: ADENOSINE, PHOSPHATE ION, conserved hypothetical protein
Authors:Lott, J.S, Paget, B, Johnston, J.M, Baker, E.N.
Deposit date:2006-04-04
Release date:2006-06-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The Structure of an Ancient Conserved Domain Establishes a Structural Basis for Stable Histidine Phosphorylation and Identifies a New Family of Adenosine-specific Kinases.
J.Biol.Chem., 281, 2006
1TGY
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BU of 1tgy by Molmil
Structure of E. coli Uridine Phosphorylase complexed with uracil and ribose 1-phosphate
Descriptor: 1-O-phosphono-alpha-D-ribofuranose, POTASSIUM ION, URACIL, ...
Authors:Bu, W, Settembre, E.C, Sanders, J.M, Begley, T.P, Ealick, S.E.
Deposit date:2004-05-31
Release date:2005-06-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of E. coli Uridine Phosphorylase
To be Published, 2004
1SRR
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BU of 1srr by Molmil
CRYSTAL STRUCTURE OF A PHOSPHATASE RESISTANT MUTANT OF SPORULATION RESPONSE REGULATOR SPO0F FROM BACILLUS SUBTILIS
Descriptor: CALCIUM ION, SPORULATION RESPONSE REGULATORY PROTEIN
Authors:Madhusudan, Whiteley, J.M, Hoch, J.A, Zapf, J, Xuong, N.H, Varughese, K.I.
Deposit date:1996-04-10
Release date:1997-04-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of a phosphatase-resistant mutant of sporulation response regulator Spo0F from Bacillus subtilis.
Structure, 4, 1996
2H6Z
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BU of 2h6z by Molmil
Crystal Structure of Thioredoxin Mutant E44D in Hexagonal (p61) Space Group
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
Authors:Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2006-06-01
Release date:2007-05-15
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.
Biophys.J., 89, 2005
2H71
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BU of 2h71 by Molmil
Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Thioredoxin
Authors:Gavira, J.A, Godoy-Ruiz, R, Ibarra-Molero, B, Sanchez-Ruiz, J.M.
Deposit date:2006-06-01
Release date:2007-05-15
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of Thioredoxin Mutant D47E in Hexagonal (p61) Space Group
To be Published
1AIK
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BU of 1aik by Molmil
HIV GP41 CORE STRUCTURE
Descriptor: HIV-1 GP41 GLYCOPROTEIN
Authors:Chan, D.C, Fass, D, Berger, J.M, Kim, P.S.
Deposit date:1997-04-20
Release date:1997-06-16
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:Core structure of gp41 from the HIV envelope glycoprotein.
Cell(Cambridge,Mass.), 89, 1997
2H4Y
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BU of 2h4y by Molmil
Crystal structure of human caspase-1 (Arg286->Lys) in complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic acid (z-VAD-FMK)
Descriptor: Caspase-1, N-[(benzyloxy)carbonyl]-L-valyl-N-[(2S)-1-carboxy-4-fluoro-3-oxobutan-2-yl]-L-alaninamide
Authors:Scheer, J.M, Wells, J.A, Romanowski, M.J.
Deposit date:2006-05-25
Release date:2008-03-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An allosteric circuit in caspase-1.
J.Mol.Biol., 381, 2008
1A6S
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BU of 1a6s by Molmil
M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES
Descriptor: GAG POLYPROTEIN
Authors:Mcdonnell, J.M, Fushman, D, Cahill, S.M, Zhou, W, Wolven, A, Wilson, C.B, Nelle, T.D, Resh, M.D, Wills, J, Cowburn, D.
Deposit date:1998-03-02
Release date:1998-10-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus
J.Mol.Biol., 279, 1998
2KUC
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BU of 2kuc by Molmil
Solution Structure of a putative disulphide-isomerase from Bacteroides thetaiotaomicron
Descriptor: Putative disulphide-isomerase
Authors:Harris, R, Foti, R, Seidel, R.D, Bonanno, J.B, Freeman, J, Bain, K.T, Sauder, J.M, Burley, S.K, Girvin, M.E, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2010-02-17
Release date:2010-03-02
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution Structure of a putative disulphide-isomerase from Bacteroides thetaiotaomicron
To be Published
1UNW
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BU of 1unw by Molmil
Structure Based Engineering of Internal Molecular Surfaces Of Four Helix Bundles
Descriptor: GENERAL CONTROL PROTEIN GCN4
Authors:Yadav, M.K, Redman, J.E, Alvarez-Gutierrez, J.M, Zhang, Y, Stout, C.D, Ghadiri, M.R.
Deposit date:2003-09-15
Release date:2004-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides
Biochemistry, 44, 2005
2KPN
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BU of 2kpn by Molmil
Solution NMR structure of a Bacterial Ig-like (Big_3) domain from Bacillus cereus. Northeast Structural Genomics Consortium target BcR147A
Descriptor: Bacillolysin, CALCIUM ION
Authors:Aramini, J.M, Wang, D, Ciccosanti, C.T, Janjua, H, Rost, B, Acton, T.B, Xiao, R, Swapna, G.V.T, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2009-10-16
Release date:2010-01-12
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution NMR structure of a Bacterial Ig-like (Big_3) domain from Bacillus cereus. Northeast Structural Genomics Consortium target BcR147A
To be Published
1UPC
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BU of 1upc by Molmil
Carboxyethylarginine synthase from Streptomyces clavuligerus
Descriptor: CARBOXYETHYLARGININE SYNTHASE, MAGNESIUM ION, SULFATE ION, ...
Authors:Caines, M.E.C, Elkins, J.M, Hewitson, K.S, Schofield, C.J.
Deposit date:2003-09-29
Release date:2003-11-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004
1UPA
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BU of 1upa by Molmil
Carboxyethylarginine synthase from Streptomyces clavuligerus (SeMet structure)
Descriptor: CARBOXYETHYLARGININE SYNTHASE, MAGNESIUM ION, SULFATE ION, ...
Authors:Caines, M.E.C, Elkins, J.M, Hewitson, K.S, Schofield, C.J.
Deposit date:2003-09-29
Release date:2003-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal Structure and Mechanistic Implications of N2-(2-Carboxyethyl)Arginine Synthase, the First Enzyme in the Clavulanic Acid Biosynthesis Pathway
J.Biol.Chem., 279, 2004

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數據於2024-07-17公開中

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