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2ETM
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BU of 2etm by Molmil
Crystal Structure of Focal Adhesion Kinase Domain Complexed with 7H-Pyrrolo [2,3-d] pyrimidine Derivative
Descriptor: 7-PYRIDIN-2-YL-N-(3,4,5-TRIMETHOXYPHENYL)-7H-PYRROLO[2,3-D]PYRIMIDIN-2-AMINE, Focal adhesion kinase 1
Authors:Lee, C.C.
Deposit date:2005-10-27
Release date:2006-10-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal Structure of Focal Adhesion Kinase Domain Complexed with ATP and novel 7H-Pyrrolo [2,3-d] pyrimidine scaffolds
To be Published
2EY4
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BU of 2ey4 by Molmil
Crystal Structure of a Cbf5-Nop10-Gar1 Complex
Descriptor: Probable tRNA pseudouridine synthase B, Ribosome biogenesis protein Nop10, ZINC ION, ...
Authors:Rashid, R, Liang, B, Li, H, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2005-11-09
Release date:2006-01-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structure of a Cbf5-Nop10-Gar1 complex and implications in RNA-guided pseudouridylation and dyskeratosis congenita.
Mol.Cell, 21, 2006
8GYB
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BU of 8gyb by Molmil
Crystal structure of Alongshan virus methyltransferase bound to S-adenosyl-L-homocysteine
Descriptor: Methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-22
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GYA
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BU of 8gya by Molmil
Crystal structure of Alongshan virus methyltransferase bound to Sinefungin
Descriptor: Methyltransferase, SINEFUNGIN
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.005 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GY4
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BU of 8gy4 by Molmil
Crystal structure of Alongshan virus methyltransferase
Descriptor: Methyltransferase
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
8GY9
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BU of 8gy9 by Molmil
Crystal structure of Alongshan virus methyltransferase bound to S-adenosyl-L-methionine
Descriptor: Methyltransferase, S-ADENOSYLMETHIONINE
Authors:Chen, H, Lin, S, Lu, G.W.
Deposit date:2022-09-21
Release date:2023-09-27
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and functional basis of low-affinity SAM/SAH-binding in the conserved MTase of the multi-segmented Alongshan virus distantly related to canonical unsegmented flaviviruses.
Plos Pathog., 19, 2023
5FHD
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BU of 5fhd by Molmil
Structure of Bacteroides sp Pif1 complexed with tailed dsDNA resulting in ssDNA bound complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*CP*CP*GP*GP*GP*GP*CP*CP*GP*CP*GP*C)-3'), MAGNESIUM ION, ...
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FL1
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BU of 5fl1 by Molmil
Structure of a hydrolase with an inhibitor
Descriptor: (3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-5-(hydroxymethyl)-2-(prop-2-enylamino)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d][1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Cekic, N, Heinonen, J.E, Stubbs, K.A, Roth, C, McEachern, E.J, Davies, G.J, Vocadlo, D.J.
Deposit date:2015-10-20
Release date:2016-08-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by humanO-GlcNAcase.
Chem Sci, 7, 2016
5FHF
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BU of 5fhf by Molmil
Crystal structure of Bacteroides sp Pif1 in complex with ADP-AlF4
Descriptor: ADENOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, Uncharacterized protein
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FKY
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BU of 5fky by Molmil
Structure of a hydrolase bound with an inhibitor
Descriptor: (3aR,5R,6S,7R,7aR)-2-amino-5-(hydroxymethyl)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol, GLYCEROL, O-GLCNACASE BT_4395
Authors:Cekic, N, Heinonen, J.E, Stubbs, K.A, Roth, C, McEachern, E.J, Davies, G.J, Vocadlo, D.J.
Deposit date:2015-10-20
Release date:2016-01-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by humanO-GlcNAcase.
Chem Sci, 7, 2016
5FHG
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BU of 5fhg by Molmil
Structure of unliganded Pif1 from Bacteroides sp
Descriptor: Uncharacterized protein
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FHE
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BU of 5fhe by Molmil
Crystal structure of Bacteroides Pif1 bound to ssDNA
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FHH
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BU of 5fhh by Molmil
Structure of human Pif1 helicase domain residues 200-641
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase PIF1, TETRAFLUOROALUMINATE ION
Authors:Zhou, X, Ren, W, Bharath, S.R, Song, H.
Deposit date:2015-12-22
Release date:2016-03-30
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and Functional Insights into the Unwinding Mechanism of Bacteroides sp Pif1
Cell Rep, 14, 2016
5FL0
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BU of 5fl0 by Molmil
Structure of a hydrolase with an inhibitor
Descriptor: (3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-2-(butylamino)-5-(hydroxymethyl)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d] [1,3]thiazole-6,7-diol, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Cekic, N, Heinonen, J.E, Stubbs, K.A, Roth, C, McEachern, E.J, Davies, G.J, Vocadlo, D.J.
Deposit date:2015-10-20
Release date:2016-08-31
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by humanO-GlcNAcase.
Chem Sci, 7, 2016
5H48
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BU of 5h48 by Molmil
Crystal structure of Cbln1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1
Authors:Zhong, C, Shen, J, Zhang, H, Ding, J.
Deposit date:2016-10-31
Release date:2017-09-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
5H4C
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BU of 5h4c by Molmil
Crystal structure of Cbln4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Protein Cbln4
Authors:Zhong, C, Shen, J, Zhang, H, Ding, J.
Deposit date:2016-10-31
Release date:2017-09-06
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions.
Cell Rep, 20, 2017
5GPO
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BU of 5gpo by Molmil
The sensor domain structure of the zinc-responsive histidine kinase CzcS from Pseudomonas Aeruginosa
Descriptor: SULFATE ION, Sensor protein CzcS, ZINC ION
Authors:Wang, D, Chen, W.Z, Huang, S.Q, Liu, X.C, Hu, Q.Y, Wei, T.B, Gan, J.H, Chen, H.
Deposit date:2016-08-03
Release date:2017-08-09
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.701 Å)
Cite:Structural basis of Zn(II) induced metal detoxification and antibiotic resistance by histidine kinase CzcS in Pseudomonas aeruginosa
PLoS Pathog., 13, 2017
3BM8
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BU of 3bm8 by Molmil
crystal structure of YopH mutant D356A complexed with irreversible inhibitor PVSN
Descriptor: Tyrosine-protein phosphatase yopH, phenyl ethenesulfonate
Authors:Zhang, Z.Y, Liu, S.J.
Deposit date:2007-12-12
Release date:2008-06-17
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
J.Am.Chem.Soc., 130, 2008
3BLU
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BU of 3blu by Molmil
crystal structure YopH complexed with inhibitor PVS
Descriptor: (ethenylsulfonyl)benzene, Tyrosine-protein phosphatase yopH
Authors:Liu, S, Zhang, Z.-Y.
Deposit date:2007-12-11
Release date:2008-10-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases
J.Am.Chem.Soc., 130, 2008
3BLT
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BU of 3blt by Molmil
Crystal structures of YopH complexed with PVSN and PVS, inhibitors of YopH which co-valent bind to Cys of active site
Descriptor: Tyrosine-protein phosphatase yopH, phenyl ethenesulfonate
Authors:Liu, S, Zhang, Z.-Y.
Deposit date:2007-12-11
Release date:2009-02-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
J.Am.Chem.Soc., 130, 2008
6JCS
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BU of 6jcs by Molmil
AAV5 in complex with AAVR
Descriptor: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-08-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCR
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BU of 6jcr by Molmil
AAV1 in neutral condition at 3.07 Ang
Descriptor: Capsid protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-10-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.07 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCQ
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BU of 6jcq by Molmil
AAV1 in complex with AAVR
Descriptor: Capsid protein, Dyslexia-associated protein KIAA0319-like protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-10-23
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
6JCT
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BU of 6jct by Molmil
AAV5 in neutral condition at 3.18 Ang
Descriptor: Capsid protein
Authors:Lou, Z, Zhang, R.
Deposit date:2019-01-30
Release date:2019-07-31
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.18 Å)
Cite:Divergent engagements between adeno-associated viruses with their cellular receptor AAVR.
Nat Commun, 10, 2019
2Q6S
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BU of 2q6s by Molmil
2.4 angstrom crystal structure of PPAR gamma complexed to BVT.13 without co-activator peptides
Descriptor: 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID, Peroxisome Proliferator-Activated Receptor gamma
Authors:Bruning, J.B, Nettles, K.W.
Deposit date:2007-06-01
Release date:2007-10-23
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Partial Agonists Activate PPARgamma Using a Helix 12 Independent Mechanism
Structure, 15, 2007

224004

數據於2024-08-21公開中

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