3LDJ
| Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding | Descriptor: | 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, Pancreatic trypsin inhibitor | Authors: | Yang, I.S, Kim, T.G, Park, B.S, Kim, K.H. | Deposit date: | 2010-01-13 | Release date: | 2010-09-15 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding. Biochem.Biophys.Res.Commun., 2010
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5TRL
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3LDM
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5TRM
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3MYI
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7D27
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2KAL
| NMR structure of fully methylated GATC site | Descriptor: | 5'-D(*DCP*DGP*DCP*DAP*DGP*(6MA)P*DTP*DCP*DTP*DCP*DGP*DC)-3', 5'-D(*DGP*DCP*DGP*DAP*DGP*(6MA)P*DTP*DCP*DTP*DGP*DCP*DG)-3' | Authors: | Bang, J, Bae, S, Park, C, Lee, J, Choi, B. | Deposit date: | 2008-11-09 | Release date: | 2009-02-10 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural and dynamics study of DNA dodecamer duplexes that contain un-, hemi-, or fully methylated GATC sites. J.Am.Chem.Soc., 130, 2008
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7CPZ
| Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis | Descriptor: | BIOTIN, Mature Streptoavidin-C1 | Authors: | Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y. | Deposit date: | 2020-08-08 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites. Iucrj, 8, 2021
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7CQ0
| Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis | Descriptor: | Mature Streptoavidin-C1 | Authors: | Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y. | Deposit date: | 2020-08-08 | Release date: | 2021-07-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites. Iucrj, 8, 2021
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5CEZ
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5CEY
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5D6W
| Crystal structure of double tudor domain of human lysine demethylase KDM4A | Descriptor: | Lysine-specific demethylase 4A, S,R MESO-TARTARIC ACID | Authors: | Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-08-13 | Release date: | 2015-11-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.992 Å) | Cite: | Reader domain specificity and lysine demethylase-4 family function. Nat Commun, 7, 2016
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5D6Y
| Crystal structure of double tudor domain of human lysine demethylase KDM4A complexed with histone H3K23me3 | Descriptor: | Lysine-specific demethylase 4A, peptide H3K23me3 (19-28) | Authors: | Wang, F, Su, Z, Miller, M.D, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-08-13 | Release date: | 2016-02-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.287 Å) | Cite: | Reader domain specificity and lysine demethylase-4 family function. Nat Commun, 7, 2016
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5D6X
| Crystal structure of double tudor domain of human lysine demethylase KDM4A | Descriptor: | Lysine-specific demethylase 4A, SULFATE ION | Authors: | Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-08-13 | Release date: | 2015-11-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.153 Å) | Cite: | Reader domain specificity and lysine demethylase-4 family function. Nat Commun, 7, 2016
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4P9M
| Crystal structure of 8ANC195 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain | Authors: | Scharf, L, Bjorkman, P.J. | Deposit date: | 2014-04-04 | Release date: | 2014-05-21 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike. Cell Rep, 7, 2014
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4NCK
| Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation | Descriptor: | CHLORIDE ION, DNA double-strand break repair Rad50 ATPase, MAGNESIUM ION, ... | Authors: | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | Deposit date: | 2013-10-24 | Release date: | 2014-03-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33, 2014
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4P9H
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5D7G
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5CEX
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4NCH
| Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation | Descriptor: | DNA double-strand break repair Rad50 ATPase, SULFATE ION | Authors: | Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S. | Deposit date: | 2013-10-24 | Release date: | 2014-03-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling. Embo J., 33, 2014
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5CUF
| X-ray crystal structure of SeMet human Sestrin2 | Descriptor: | Sestrin-2 | Authors: | Kim, H, An, S, Ro, S.-H, Lee, J.H, Cho, U.-S. | Deposit date: | 2015-07-24 | Release date: | 2016-01-13 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains. Nat Commun, 6, 2015
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2OF4
| crystal structure of furanopyrimidine 1 bound to lck | Descriptor: | 5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE, Proto-oncogene tyrosine-protein kinase LCK | Authors: | Martin, M.W. | Deposit date: | 2007-01-02 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties. Bioorg.Med.Chem.Lett., 17, 2007
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2OFV
| crystal structure of aminoquinazoline 1 bound to Lck | Descriptor: | 3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE, Proto-oncogene tyrosine-protein kinase LCK | Authors: | Huang, X. | Deposit date: | 2007-01-04 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity J.Med.Chem., 49, 2006
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3SFU
| crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin | Descriptor: | 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ... | Authors: | Kim, K.H, Alam, I. | Deposit date: | 2011-06-14 | Release date: | 2012-05-09 | Method: | X-RAY DIFFRACTION (2.501 Å) | Cite: | Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin. Virology, 426, 2012
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2OFU
| x-ray crystal structure of 2-aminopyrimidine carbamate 43 bound to Lck | Descriptor: | 2,6-DIMETHYLPHENYL 2-(3,5-DIMETHOXY-4-(3-(4-METHYLPIPERAZIN-1-YL)PROPOXY)PHENYLAMINO)PYRIMIDIN- 4-YL(2,4-DIMETHOXYPHENYL)CARBAMATE, Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION | Authors: | Huang, X. | Deposit date: | 2007-01-04 | Release date: | 2007-02-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity J.Med.Chem., 49, 2006
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