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3LDJ
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BU of 3ldj by Molmil
Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding
Descriptor: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, Pancreatic trypsin inhibitor
Authors:Yang, I.S, Kim, T.G, Park, B.S, Kim, K.H.
Deposit date:2010-01-13
Release date:2010-09-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding.
Biochem.Biophys.Res.Commun., 2010
5TRL
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BU of 5trl by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain
Descriptor: Histone acetyltransferase KAT2A, SUCCINYL-COENZYME A
Authors:Guo, Y.R, Tao, Y.J.
Deposit date:2016-10-26
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.299 Å)
Cite:KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.
Nature, 552, 2017
3LDM
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BU of 3ldm by Molmil
Crystal structure of aprotinin in complex with sucrose octasulfate: unusual interactions and implication for heparin binding
Descriptor: Pancreatic trypsin inhibitor
Authors:Yang, I.S, Kim, T.G, Park, B.S, Kim, K.H.
Deposit date:2010-01-13
Release date:2010-06-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of aprotinin and its complex with sucrose octasulfate reveal multiple modes of interactions with implications for heparin binding.
Biochem.Biophys.Res.Commun., 2010
5TRM
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BU of 5trm by Molmil
Crystal structure of human GCN5 histone acetyltransferase domain
Descriptor: Histone acetyltransferase KAT2A
Authors:Guo, Y.R, Tao, Y.J.
Deposit date:2016-10-26
Release date:2017-12-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.
Nature, 552, 2017
3MYI
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BU of 3myi by Molmil
Human metavinculin tail domain
Descriptor: Vinculin
Authors:Izard, T, Rangarajan, E.S.
Deposit date:2010-05-10
Release date:2010-05-26
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:A helix replacement mechanism directs metavinculin functions.
Plos One, 5, 2010
7D27
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BU of 7d27 by Molmil
Structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase
Descriptor: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
Authors:Park, H.H, Jeong, K.H.
Deposit date:2020-09-16
Release date:2021-07-28
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Wide-open conformation of UDP-MurNc-tripeptide ligase revealed by the substrate-free structure of MurE from Acinetobacter baumannii.
Febs Lett., 595, 2021
2KAL
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BU of 2kal by Molmil
NMR structure of fully methylated GATC site
Descriptor: 5'-D(*DCP*DGP*DCP*DAP*DGP*(6MA)P*DTP*DCP*DTP*DCP*DGP*DC)-3', 5'-D(*DGP*DCP*DGP*DAP*DGP*(6MA)P*DTP*DCP*DTP*DGP*DCP*DG)-3'
Authors:Bang, J, Bae, S, Park, C, Lee, J, Choi, B.
Deposit date:2008-11-09
Release date:2009-02-10
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural and dynamics study of DNA dodecamer duplexes that contain un-, hemi-, or fully methylated GATC sites.
J.Am.Chem.Soc., 130, 2008
7CPZ
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BU of 7cpz by Molmil
Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis
Descriptor: BIOTIN, Mature Streptoavidin-C1
Authors:Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y.
Deposit date:2020-08-08
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites.
Iucrj, 8, 2021
7CQ0
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BU of 7cq0 by Molmil
Crystal structure of Streptoavidin-C1 from Streptomyces cinamonensis
Descriptor: Mature Streptoavidin-C1
Authors:Jeon, B.J, Kim, S, Lee, J.-H, Kim, M.S, Hwang, K.Y.
Deposit date:2020-08-08
Release date:2021-07-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Insights into the structure of mature streptavidin C1 from Streptomyces cinnamonensis reveal the self-binding of the extension C-terminal peptide to biotin-binding sites.
Iucrj, 8, 2021
5CEZ
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BU of 5cez by Molmil
Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with an early putative precursor of the PGT121 family at 3.0 Angstrom
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Fab Heavy Chain, ...
Authors:Wilson, I.A, Garces, F.
Deposit date:2015-07-08
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.031 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5CEY
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BU of 5cey by Molmil
Crystal Structure of Fab 9H+3L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
Descriptor: 1-DEOXY-1-THIO-HEPTAETHYLENE GLYCOL, Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, ...
Authors:Wilson, I.A, Garces, F.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.387 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
5D6W
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BU of 5d6w by Molmil
Crystal structure of double tudor domain of human lysine demethylase KDM4A
Descriptor: Lysine-specific demethylase 4A, S,R MESO-TARTARIC ACID
Authors:Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2015-08-13
Release date:2015-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.992 Å)
Cite:Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
5D6Y
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BU of 5d6y by Molmil
Crystal structure of double tudor domain of human lysine demethylase KDM4A complexed with histone H3K23me3
Descriptor: Lysine-specific demethylase 4A, peptide H3K23me3 (19-28)
Authors:Wang, F, Su, Z, Miller, M.D, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2015-08-13
Release date:2016-02-10
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.287 Å)
Cite:Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
5D6X
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BU of 5d6x by Molmil
Crystal structure of double tudor domain of human lysine demethylase KDM4A
Descriptor: Lysine-specific demethylase 4A, SULFATE ION
Authors:Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
Deposit date:2015-08-13
Release date:2015-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.153 Å)
Cite:Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
4P9M
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BU of 4p9m by Molmil
Crystal structure of 8ANC195 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 Fab heavy chain, 8ANC195 light chain
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
4NCK
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BU of 4nck by Molmil
Crystal Structure of Pyrococcus furiosis Rad50 R797G mutation
Descriptor: CHLORIDE ION, DNA double-strand break repair Rad50 ATPase, MAGNESIUM ION, ...
Authors:Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S.
Deposit date:2013-10-24
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
4P9H
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BU of 4p9h by Molmil
Crystal structure of 8ANC195 Fab in complex with gp120 of 93TH057 HIV-1 and soluble CD4 D1D2
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Scharf, L, Bjorkman, P.J.
Deposit date:2014-04-04
Release date:2014-05-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike.
Cell Rep, 7, 2014
5D7G
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BU of 5d7g by Molmil
Structure of human ATG5 E122D-ATG16L1 complex at 3.0 Angstroms
Descriptor: Autophagy protein 5, Autophagy-related protein 16-1
Authors:Qiu, Y, Schulman, B.A.
Deposit date:2015-08-13
Release date:2016-02-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
Elife, 5, 2016
5CEX
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BU of 5cex by Molmil
Crystal Structure of Fab 32H+109L, a putative precursor of the PGT121 family of potent HIV-1 antibodies
Descriptor: Antibody 9H+3L Fab heavy chain, Antibody 9H+3L Fab light chain, GLYCEROL, ...
Authors:Garces, F, Wilson, I.A.
Deposit date:2015-07-07
Release date:2015-12-23
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.105 Å)
Cite:Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans.
Immunity, 43, 2015
4NCH
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BU of 4nch by Molmil
Crystal Structure of Pyrococcus furiosis Rad50 L802W mutation
Descriptor: DNA double-strand break repair Rad50 ATPase, SULFATE ION
Authors:Classen, S, Williams, G.J, Arvai, A.S, Williams, R.S.
Deposit date:2013-10-24
Release date:2014-03-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling.
Embo J., 33, 2014
5CUF
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BU of 5cuf by Molmil
X-ray crystal structure of SeMet human Sestrin2
Descriptor: Sestrin-2
Authors:Kim, H, An, S, Ro, S.-H, Lee, J.H, Cho, U.-S.
Deposit date:2015-07-24
Release date:2016-01-13
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Janus-faced Sestrin2 controls ROS and mTOR signalling through two separate functional domains.
Nat Commun, 6, 2015
2OF4
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BU of 2of4 by Molmil
crystal structure of furanopyrimidine 1 bound to lck
Descriptor: 5,6-DIPHENYL-N-(2-PIPERAZIN-1-YLETHYL)FURO[2,3-D]PYRIMIDIN-4-AMINE, Proto-oncogene tyrosine-protein kinase LCK
Authors:Martin, M.W.
Deposit date:2007-01-02
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: Synthesis, SAR, and pharmacokinetic properties.
Bioorg.Med.Chem.Lett., 17, 2007
2OFV
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BU of 2ofv by Molmil
crystal structure of aminoquinazoline 1 bound to Lck
Descriptor: 3-(2-AMINOQUINAZOLIN-6-YL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE, Proto-oncogene tyrosine-protein kinase LCK
Authors:Huang, X.
Deposit date:2007-01-04
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity
J.Med.Chem., 49, 2006
3SFU
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BU of 3sfu by Molmil
crystal structure of murine norovirus RNA dependent RNA polymerase in complex with ribavirin
Descriptor: 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide, GLYCEROL, MAGNESIUM ION, ...
Authors:Kim, K.H, Alam, I.
Deposit date:2011-06-14
Release date:2012-05-09
Method:X-RAY DIFFRACTION (2.501 Å)
Cite:Crystal structures of murine norovirus-1 RNA-dependent RNA polymerase in complex with 2-thiouridine or ribavirin.
Virology, 426, 2012
2OFU
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BU of 2ofu by Molmil
x-ray crystal structure of 2-aminopyrimidine carbamate 43 bound to Lck
Descriptor: 2,6-DIMETHYLPHENYL 2-(3,5-DIMETHOXY-4-(3-(4-METHYLPIPERAZIN-1-YL)PROPOXY)PHENYLAMINO)PYRIMIDIN- 4-YL(2,4-DIMETHOXYPHENYL)CARBAMATE, Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION
Authors:Huang, X.
Deposit date:2007-01-04
Release date:2007-02-27
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck: Synthesis, SAR, and in Vivo Antiinflammatory Activity
J.Med.Chem., 49, 2006

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數據於2024-06-12公開中

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