3PN9
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4IPT
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![BU of 4ipt by Molmil](/molmil-images/mine/4ipt) | The crystal structure of a short-chain dehydrogenases/reductase (ethylated) from Veillonella parvula DSM 2008 | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ... | Authors: | Tan, K, Hatzos-Skintges, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-01-10 | Release date: | 2013-02-06 | Last modified: | 2019-11-27 | Method: | X-RAY DIFFRACTION (1.546 Å) | Cite: | The crystal structure of a short-chain dehydrogenases/reductase (ethylated) from Veillonella parvula DSM 2008 To be Published
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1KK1
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![BU of 1kk1 by Molmil](/molmil-images/mine/1kk1) | Structure of the large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi-G235D mutant complexed with GDPNP-Mg2+ | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ZINC ION, ... | Authors: | Schmitt, E, Blanquet, S, Mechulam, Y. | Deposit date: | 2001-12-06 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
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3PEB
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![BU of 3peb by Molmil](/molmil-images/mine/3peb) | The Structure of a Creatine_N Superfamily domain of a dipeptidase from Streptococcus thermophilus. | Descriptor: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Dipeptidase, ... | Authors: | Cuff, M.E, Mack, J.C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-10-25 | Release date: | 2010-11-03 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | The Structure of a Creatine_N Superfamily domain of a dipeptidase from Streptococcus thermophilus. TO BE PUBLISHED
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2XC8
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![BU of 2xc8 by Molmil](/molmil-images/mine/2xc8) | Crystal structure of the gene 22 product of the Bacillus subtilis SPP1 phage | Descriptor: | GENE 22 PRODUCT | Authors: | Veesler, D, Blangy, S, Tavares, P, Campanacci, V, Cambillau, C. | Deposit date: | 2010-04-19 | Release date: | 2010-06-09 | Last modified: | 2017-07-12 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystal Structure of Bacillus Subtilis Spp1 Phage Gp22 Shares Fold Similarity with a Domain of Lactococcal Phage P2 Rbp. Protein Sci., 19, 2010
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2XHD
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![BU of 2xhd by Molmil](/molmil-images/mine/2xhd) | Crystal structure of N-((2S)-5-(6-fluoro-3-pyridinyl)-2,3-dihydro-1H- inden-2-yl)-2-propanesulfonamide in complex with the ligand binding domain of the human GluA2 receptor | Descriptor: | GLUTAMATE RECEPTOR 2, GLUTAMIC ACID, N-[(2S)-5-(6-FLUORO-3-PYRIDINYL)-2,3-DIHYDRO-1H-INDEN-2-YL]-2-PROPANESULFONAMIDE, ... | Authors: | Ward, S.E, Harries, M, Aldegheri, L, Andreotti, D, Ballantine, S, Bax, B.D, Harris, A.J, Harker, A.J, Lund, J, Melarange, R, Mingardi, A, Mookherjee, C, Mosley, J, Neve, M, Oliosi, B, Profeta, R, Smith, K.J, Smith, P.W, Spada, S, Thewlis, K.M, Yusaf, S.P. | Deposit date: | 2010-06-14 | Release date: | 2010-07-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of N-[(2S)-5-(6-Fluoro-3-Pyridinyl)-2,3-Dihydro-1H-Inden-2-Yl]-2-Propanesulfonamide, a Novel Clinical Ampa Receptor Positive Modulator. J.Med.Chem., 53, 2010
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1MKH
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4I19
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![BU of 4i19 by Molmil](/molmil-images/mine/4i19) | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. | Descriptor: | ACETATE ION, Epoxide hydrolase, FORMIC ACID | Authors: | Tan, K, Bigelow, L, Clancy, S, Babnigg, G, Bingman, C.A, Yennamalli, R, Lohman, J, Ma, M, Shen, B, Phillips Jr, G.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2012-11-20 | Release date: | 2012-12-05 | Last modified: | 2013-01-30 | Method: | X-RAY DIFFRACTION (2.148 Å) | Cite: | The crystal structure of an epoxide hydrolase from Streptomyces carzinostaticus subsp. neocarzinostaticus. To be Published
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3QQZ
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![BU of 3qqz by Molmil](/molmil-images/mine/3qqz) | Crystal structure of the C-terminal domain of the yjiK protein from Escherichia coli CFT073 | Descriptor: | CALCIUM ION, Putative uncharacterized protein yjiK | Authors: | Stein, A, Chhor, G, Nocek, B, Fenske, R.J, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-02-16 | Release date: | 2011-03-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of the C-terminal domain of the yjiK protein from Escherichia coli CFT073 TO BE PUBLISHED
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5EH0
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![BU of 5eh0 by Molmil](/molmil-images/mine/5eh0) | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach | Descriptor: | DIMETHYL SULFOXIDE, Dual specificity protein kinase TTK, N2-(2-Methoxy-4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine | Authors: | Innocenti, P, Woodward, H.L, Solanki, S, Naud, N, Westwood, I.M, Cronin, N, Hayes, A, Roberts, J, Henley, A.T, Baker, R, Faisal, A, Mak, G, Box, G, Valenti, M, De Haven Brandon, A, O'Fee, L, Saville, J, Schmitt, J, Burke, R, van Montfort, R.L.M, Raymaud, F.I, Eccles, S.A, Linardopoulos, S, Blagg, J, Hoelder, S. | Deposit date: | 2015-10-27 | Release date: | 2016-04-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach. J.Med.Chem., 59, 2016
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3QZ6
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3RNR
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![BU of 3rnr by Molmil](/molmil-images/mine/3rnr) | Crystal Structure of Stage II Sporulation E Family Protein from Thermanaerovibrio acidaminovorans | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, GLYCEROL, ... | Authors: | Kim, Y, Li, H, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-22 | Release date: | 2011-06-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Stage II Sporulation E Family Protein from Thermanaerovibrio acidaminovorans To be Published
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3RCN
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![BU of 3rcn by Molmil](/molmil-images/mine/3rcn) | Crystal Structure of Beta-N-Acetylhexosaminidase from Arthrobacter aurescens | Descriptor: | ACETIC ACID, Beta-N-acetylhexosaminidase, GLYCEROL, ... | Authors: | Kim, Y, Chhor, G, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-03-31 | Release date: | 2011-06-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.514 Å) | Cite: | Crystal Structure of Beta-N-Acetylhexosaminidase from Arthrobacter aurescens To be Published
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5EI6
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![BU of 5ei6 by Molmil](/molmil-images/mine/5ei6) | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach | Descriptor: | DIMETHYL SULFOXIDE, Dual specificity protein kinase TTK, ~{N}-(2,4-dimethoxyphenyl)-5-(1-methylpyrazol-4-yl)isoquinolin-3-amine | Authors: | Innocenti, P, Woodward, H.L, Solanki, S, Naud, N, Westwood, I.M, Cronin, N, Hayes, A, Roberts, J, Henley, A.T, Baker, R, Faisal, A, Mak, G, Box, G, Valenti, M, De Haven Brandon, A, O'Fee, L, Saville, J, Schmitt, J, Burke, R, van Montfort, R.L.M, Raymaud, F.I, Eccles, S.A, Linardopoulos, S, Blagg, J, Hoelder, S. | Deposit date: | 2015-10-29 | Release date: | 2016-04-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach. J.Med.Chem., 59, 2016
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5EHY
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![BU of 5ehy by Molmil](/molmil-images/mine/5ehy) | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach | Descriptor: | 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 4-(furan-3-yl)-3-phenyl-2~{H}-pyrazolo[4,3-c]pyridine, ... | Authors: | Innocenti, P, Woodward, H.L, Solanki, S, Naud, N, Westwood, I.M, Cronin, N, Hayes, A, Roberts, J, Henley, A.T, Baker, R, Faisal, A, Mak, G, Box, G, Valenti, M, De Haven Brandon, A, O'Fee, L, Saville, J, Schmitt, J, Burke, R, van Montfort, R.L.M, Raymaud, F.I, Eccles, S.A, Linardopoulos, S, Blagg, J, Hoelder, S. | Deposit date: | 2015-10-29 | Release date: | 2016-04-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach. J.Med.Chem., 59, 2016
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5EI8
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![BU of 5ei8 by Molmil](/molmil-images/mine/5ei8) | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle kinase 1 (MPS1) Using a Structure-Based Hydridization Approach | Descriptor: | DIMETHYL SULFOXIDE, Dual specificity protein kinase TTK, ~{N}-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-(1-methylpyrazol-4-yl)pyrido[3,4-d]pyrimidin-2-amine | Authors: | Innocenti, P, Woodward, H.L, Solanki, S, Naud, N, Westwood, I.M, Cronin, N, Hayes, A, Roberts, J, Henley, A.T, Baker, R, Faisal, A, Mak, G, Box, G, Valenti, M, De Haven Brandon, A, O'Fee, L, Saville, J, Schmitt, J, Burke, R, van Montfort, R.L.M, Raymaud, F.I, Eccles, S.A, Linardopoulos, S, Blagg, J, Hoelder, S. | Deposit date: | 2015-10-29 | Release date: | 2016-04-20 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach. J.Med.Chem., 59, 2016
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3RQZ
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![BU of 3rqz by Molmil](/molmil-images/mine/3rqz) | Crystal structure of metallophosphoesterase from Sphaerobacter thermophilus | Descriptor: | ACETATE ION, Metallophosphoesterase, ZINC ION | Authors: | Chang, C, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-28 | Release date: | 2011-05-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of metallophosphoesterase from Sphaerobacter thermophilus To be Published
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4KTB
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![BU of 4ktb by Molmil](/molmil-images/mine/4ktb) | The crystal structure of posible asymmetric diadenosine tetraphosphate (Ap(4)A) hydrolases from Jonesia denitrificans DSM 20603 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Putative uncharacterized protein, ... | Authors: | Tan, K, Kim, Y, Wu, R, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2013-05-20 | Release date: | 2013-06-05 | Method: | X-RAY DIFFRACTION (1.936 Å) | Cite: | The crystal structure of posible asymmetric diadenosine tetraphosphate (Ap(4)A) hydrolases from Jonesia denitrificans DSM 20603 To be Published
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4KND
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![BU of 4knd by Molmil](/molmil-images/mine/4knd) | Thioredoxin from Anaeromyxobacter dehalogenans. | Descriptor: | Thioredoxin | Authors: | Osipiuk, J, Hatzos-Skintges, C, Clancy, S, Adkins, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP) | Deposit date: | 2013-05-09 | Release date: | 2013-05-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Thioredoxin from Anaeromyxobacter dehalogenans. To be Published
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1KK3
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![BU of 1kk3 by Molmil](/molmil-images/mine/1kk3) | Structure of the wild-type large gamma subunit of initiation factor eIF2 from Pyrococcus abyssi complexed with GDP-Mg2+ | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ZINC ION, ... | Authors: | Schmitt, E, Blanquet, S, Mechulam, Y. | Deposit date: | 2001-12-06 | Release date: | 2002-04-10 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The large subunit of initiation factor aIF2 is a close structural homologue of elongation factors. EMBO J., 21, 2002
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3OOV
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![BU of 3oov by Molmil](/molmil-images/mine/3oov) | Crystal structure of a methyl-accepting chemotaxis protein, residues 122 to 287 | Descriptor: | GLYCEROL, Methyl-accepting chemotaxis protein, putative | Authors: | Joachimiak, A, Duke, N.E.C, Hatzos-Skintges, C, Mulligan, R, Clancy, S, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-08-31 | Release date: | 2010-09-08 | Last modified: | 2017-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a methyl-accepting chemotaxis protein, residues 122 to 287 To be Published
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3RQ1
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![BU of 3rq1 by Molmil](/molmil-images/mine/3rq1) | Crystal Structure of Aminotransferase Class I and II from Veillonella parvula | Descriptor: | 2-OXOGLUTARIC ACID, Aminotransferase class I and II, CHLORIDE ION, ... | Authors: | Kim, Y, Hatzos-Skintges, C, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-04-27 | Release date: | 2011-05-18 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of Aminotransferase Class I and II from Veillonella parvula To be Published
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1MNB
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![BU of 1mnb by Molmil](/molmil-images/mine/1mnb) | BIV TAT PEPTIDE (RESIDUES 68-81), NMR, MINIMIZED AVERAGE STRUCTURE | Descriptor: | BIV TAR RNA, BIV TAT PEPTIDE | Authors: | Puglisi, J.D, Chen, L, Blanchard, S, Frankel, A.D. | Deposit date: | 1996-07-25 | Release date: | 1997-01-27 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of a bovine immunodeficiency virus Tat-TAR peptide-RNA complex. Science, 270, 1995
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3PFM
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![BU of 3pfm by Molmil](/molmil-images/mine/3pfm) | Crystal structure of a EAL domain of GGDEF domain protein from Pseudomonas fluorescens Pf | Descriptor: | GGDEF domain protein | Authors: | Nocek, B, Stein, A, Marshall, N, Clancy, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-10-28 | Release date: | 2010-11-10 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.908 Å) | Cite: | Crystal structure of a EAL domain of GGDEF domain protein from Pseudomonas fluorescens Pf TO BE PUBLISHED
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2YAK
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![BU of 2yak by Molmil](/molmil-images/mine/2yak) | Structure of death-associated protein Kinase 1 (dapk1) in complex with a ruthenium octasporine ligand (OSV) | Descriptor: | DEATH-ASSOCIATED PROTEIN KINASE 1, RUTHENIUM OCTASPORINE 4 | Authors: | Feng, L, Geisselbrecht, Y, Blanck, S, Wilbuer, A, Atilla-Gokcumen, G.E, Filippakopoulos, P, Kraeling, K, Celik, M.A, Harms, K, Maksimoska, J, Marmorstein, R, Frenking, G, Knapp, S, Essen, L.-O, Meggers, E. | Deposit date: | 2011-02-23 | Release date: | 2011-04-27 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structurally Sophisticated Octahedral Metal Complexes as Highly Selective Protein Kinase Inhibitors. J.Am.Chem.Soc., 133, 2011
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