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2YSZ
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BU of 2ysz by Molmil
Solution structure of the chimera of the C-terminal PID domain of Fe65L and the C-terminal tail peptide of APP
Descriptor: Amyloid beta A4 precursor protein-binding family B member 2 and Amyloid beta A4 protein
Authors:Li, H, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode
J.Biol.Chem., 283, 2008
2YTW
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BU of 2ytw by Molmil
Solution structure of the PDZ-domain of human protease HTRA 1 precursor
Descriptor: Serine protease HTRA1
Authors:Goroncy, A.K, Saito, K, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the PDZ-domain of human protease HTRA 1 precursor
To be Published
2YRP
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BU of 2yrp by Molmil
Solution structure of the TIG domain from Human Nuclear factor of activated T-cells, cytoplasmic 4
Descriptor: Nuclear factor of activated T-cells, cytoplasmic 4
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-02
Release date:2008-02-12
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the TIG domain from Human Nuclear factor of activated T-cells, cytoplasmic 4
To be Published
2YT2
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BU of 2yt2 by Molmil
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Descriptor: Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor
Authors:Li, H, Koshiba, S, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2
J.Struct.Funct.Genom., 11, 2010
2YT0
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BU of 2yt0 by Molmil
Solution structure of the chimera of the C-terminal tail peptide of APP and the C-terminal PID domain of Fe65L
Descriptor: Amyloid beta A4 protein and Amyloid beta A4 precursor protein-binding family B member 2
Authors:Li, H, Koshiba, S, Tochio, N, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode
J.Biol.Chem., 283, 2008
2YS4
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BU of 2ys4 by Molmil
Solution structure of the N-terminal PapD-like domain of HYDIN protein from human
Descriptor: Hydrocephalus-inducing protein homolog
Authors:Li, H, Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-03
Release date:2008-04-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal PapD-like domain of HYDIN protein from human
To be Published
2YT1
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BU of 2yt1 by Molmil
Solution structure of the chimera of the C-terminal tail peptide of APP and the C-terminal PID domain of Fe65L
Descriptor: Amyloid beta A4 protein and Amyloid beta A4 precursor protein-binding family B member 2
Authors:Li, H, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode
J.Biol.Chem., 283, 2008
3PP0
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BU of 3pp0 by Molmil
Crystal Structure of the Kinase domain of Human HER2 (erbB2).
Descriptor: 2-{2-[4-({5-chloro-6-[3-(trifluoromethyl)phenoxy]pyridin-3-yl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethoxy}ethanol, Receptor tyrosine-protein kinase erbB-2
Authors:Skene, R.J, Aertgeerts, K, Sogabe, S.
Deposit date:2010-11-23
Release date:2011-03-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein.
J.Biol.Chem., 286, 2011
3POZ
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BU of 3poz by Molmil
EGFR Kinase domain complexed with tak-285
Descriptor: Epidermal growth factor receptor, N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide, SULFATE ION
Authors:Aertgeerts, K, Skene, R, Sogabe, S.
Deposit date:2010-11-23
Release date:2011-03-30
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein.
J.Biol.Chem., 286, 2011
3RCD
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BU of 3rcd by Molmil
HER2 Kinase Domain Complexed with TAK-285
Descriptor: N-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5H-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-3-hydroxy-3-methylbutanamide, Receptor tyrosine-protein kinase erbB-2
Authors:Aertgeerts, K, Skene, R, Sogabe, S.
Deposit date:2011-03-30
Release date:2011-11-23
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Design and Synthesis of Novel Human Epidermal Growth Factor Receptor 2 (HER2)/Epidermal Growth Factor Receptor (EGFR) Dual Inhibitors Bearing a Pyrrolo[3,2-d]pyrimidine Scaffold.
J.Med.Chem., 54, 2011
2YT5
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BU of 2yt5 by Molmil
Solution structure of the PHD domain of Metal-response element-binding transcription factor 2
Descriptor: Metal-response element-binding transcription factor 2, ZINC ION
Authors:Masuda, K, Muto, Y, Isono, K, Watanabe, S, Harada, T, Kigawa, T, Koseki, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-04-05
Release date:2008-04-15
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the PHD domain of Metal-response element-binding transcription factor 2
To be Published
3B43
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BU of 3b43 by Molmil
I-band fragment I65-I70 from titin
Descriptor: Titin
Authors:von Castelmur, E, Marino, M, Labeit, D, Labeit, S, Mayans, O.
Deposit date:2007-10-23
Release date:2008-01-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain
Proc.Natl.Acad.Sci.Usa, 105, 2008
2DJ4
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BU of 2dj4 by Molmil
Solution structure of the 13th filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-31
Release date:2006-10-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 13th filamin domain from human Filamin-B
To be Published
2DS4
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BU of 2ds4 by Molmil
Solution structure of the filamin domain from human tripartite motif protein 45
Descriptor: Tripartite motif protein 45
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-06-21
Release date:2006-12-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the filamin domain from human tripartite motif protein 45
To be Published
2DHZ
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BU of 2dhz by Molmil
Solution Structure of the RA Domain in the Human Link Guanine Nucleotide Exchange Factor II (Link-GEFII)
Descriptor: Rap guanine nucleotide exchange factor (GEF)-like 1
Authors:Zhao, C, Kigawa, T, Yoneyama, M, Koshiba, S, Harada, T, Watanabe, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-27
Release date:2006-09-27
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution Structure of the RA Domain in the Human Link Guanine Nucleotide Exchange Factor II (Link-GEFII)
To be Published
2DIC
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BU of 2dic by Molmil
Solution structure of the 12th filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-29
Release date:2006-09-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 12th filamin domain from human Filamin-B
To be Published
2DMB
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BU of 2dmb by Molmil
Solution structure of the 15th Filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Tochio, N, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-04-20
Release date:2006-10-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 15th Filamin domain from human Filamin-B
To be Published
2DI9
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BU of 2di9 by Molmil
Solution structure of the 9th filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-03-29
Release date:2006-09-29
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 9th filamin domain from human Filamin-B
To be Published
2E9I
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BU of 2e9i by Molmil
Solution structure of the N-terminal extended 20th Filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-01-25
Release date:2007-07-31
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal extended 20th Filamin domain from human Filamin-B
To be Published
2EE0
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BU of 2ee0 by Molmil
Solution structures of the CA domain of human protocadherin 9
Descriptor: Protocadherin-9
Authors:Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structures of the CA domain of human protocadherin 9
To be Published
2EED
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BU of 2eed by Molmil
Solution structure of the 24th filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 24th filamin domain from human Filamin-B
To be Published
2ECI
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BU of 2eci by Molmil
Solution structure of the RING domain of the human TNF receptor-associated factor 6 protein
Descriptor: TNF receptor-associated factor 6, ZINC ION
Authors:Miyamoto, K, Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-13
Release date:2008-03-18
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the RING domain of the human TNF receptor-associated factor 6 protein
To be Published
2EE6
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BU of 2ee6 by Molmil
Solution structure of the 21th filamin domain from human Filamin-B
Descriptor: Filamin-B
Authors:Tomizawa, T, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-02-15
Release date:2007-08-21
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the 21th filamin domain from human Filamin-B
To be Published
2EKI
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BU of 2eki by Molmil
Solution structures of the TGS domain of human developmentally-regulated GTP-binding protein 1
Descriptor: Developmentally-regulated GTP-binding protein 1
Authors:Sato, M, Koshiba, S, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-23
Release date:2007-09-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structures of the TGS domain of human developmentally-regulated GTP-binding protein 1
To be Published
2ELI
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BU of 2eli by Molmil
Solution structure of the second Phorbol esters/diacylglycerol binding domain of human Protein kinase C alpha type
Descriptor: Protein kinase C alpha type, ZINC ION
Authors:Tochio, N, Koshiba, S, Saito, K, Tomizawa, T, Watanabe, S, Harada, T, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-27
Release date:2008-04-01
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution structure of the second Phorbol esters/diacylglycerol binding domain of human Protein kinase C alpha type
To be Published

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數據於2024-09-18公開中

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