7EHI
 
 | | Crystal structure of covalent maltosyl-alpha-glucosidase intermediate | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | Authors: | Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T. | | Deposit date: | 2021-03-29 | | Release date: | 2021-08-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides.
Acta Crystallogr D Struct Biol, 77, 2021
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7EHH
 | | Crystal structure of alpha-glucosidase from Weissella cibaria BKK1 in complex with maltose | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, GLYCEROL, ... | | Authors: | Krusong, K, Wangpaiboon, K, Kim, S, Mori, T, Hakoshima, T. | | Deposit date: | 2021-03-29 | | Release date: | 2021-08-11 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A GH13 alpha-glucosidase from Weissella cibaria uncommonly acts on short-chain maltooligosaccharides.
Acta Crystallogr D Struct Biol, 77, 2021
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7EVT
 | | Crystal structure of the N-terminal degron-truncated human glutamine synthetase | | Descriptor: | Glutamine synthetase | | Authors: | Chek, M.F, Kim, S.Y, Mori, T, Hakoshima, T. | | Deposit date: | 2021-05-22 | | Release date: | 2021-11-10 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Crystal structure of N-terminal degron-truncated human glutamine synthetase.
Acta Crystallogr.,Sect.F, 77, 2021
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7EBC
 | | Crystal structure of Isocitrate lyase-1 from Saccaromyces cervisiae | | Descriptor: | Isocitrate lyase, MAGNESIUM ION, TETRAETHYLENE GLYCOL | | Authors: | Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. | | Deposit date: | 2021-03-09 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
J.Struct.Biol., 213, 2021
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7EBF
 | | Cryo-EM structure of Isocitrate lyase-1 from Candida albicans | | Descriptor: | Isocitrate lyase | | Authors: | Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. | | Deposit date: | 2021-03-09 | | Release date: | 2021-06-23 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.63 Å) | | Cite: | Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
J.Struct.Biol., 213, 2021
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7EBE
 | | Crystal structure of Isocitrate lyase-1 from Candida albicans | | Descriptor: | FORMIC ACID, Isocitrate lyase, MAGNESIUM ION | | Authors: | Hiragi, K, Nishio, K, Moriyama, S, Hamaguchi, T, Mizoguchi, A, Yonekura, K, Tani, K, Mizushima, T. | | Deposit date: | 2021-03-09 | | Release date: | 2021-06-23 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.69 Å) | | Cite: | Structural insights into the targeting specificity of ubiquitin ligase for S. cerevisiae isocitrate lyase but not C. albicans isocitrate lyase.
J.Struct.Biol., 213, 2021
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8KAO
 | | Glutamate dehydrogenase-69O | | Descriptor: | 2-oxopentanoic acid, Glutamate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | Authors: | Sakuraba, H, Ohshima, T. | | Deposit date: | 2023-08-03 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structure of glutamate dehydrogenase-69O
To be published
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8KAR
 | | Glutamate dehydrogenase-AKG | | Descriptor: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, Glutamate dehydrogenase, ... | | Authors: | Sakuraba, H, Ohshima, T. | | Deposit date: | 2023-08-03 | | Release date: | 2024-08-07 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Structure of glutamate dehydrogenase-AKG
To be published
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3WDZ
 | | Crystal Structure of Keap1 in Complex with phosphorylated p62 | | Descriptor: | Kelch-like ECH-associated protein 1, Peptide from Sequestosome-1 | | Authors: | Fukutomi, T, Takagi, K, Mizushima, T, Tanaka, K, Komatsu, M, Yamamoto, M. | | Deposit date: | 2013-06-26 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.
Mol.Cell, 51, 2013
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2Z5C
 | | Crystal Structure of a Novel Chaperone Complex for Yeast 20S Proteasome Assembly | | Descriptor: | Proteasome component PUP2, Protein YPL144W, Uncharacterized protein YLR021W | | Authors: | Yashiroda, H, Mizushima, T, Okamoto, K, Kameyama, T, Hayashi, H, Kishimoto, T, Kasahara, M, Kurimoto, E, Sakata, E, Suzuki, A, Hirano, Y, Murata, S, Kato, K, Yamane, T, Tanaka, K. | | Deposit date: | 2007-07-03 | | Release date: | 2008-01-22 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
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2Z5B
 | | Crystal Structure of a Novel Chaperone Complex for Yeast 20S Proteasome Assembly | | Descriptor: | Protein YPL144W, Uncharacterized protein YLR021W | | Authors: | Yashiroda, H, Mizushima, T, Okamoto, K, Kameyama, T, Hayashi, H, Kishimoto, T, Kasahara, M, Kurimoto, E, Sakata, E, Suzuki, A, Hirano, Y, Murata, S, Kato, K, Yamane, T, Tanaka, K. | | Deposit date: | 2007-07-03 | | Release date: | 2008-01-22 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomes
Nat.Struct.Mol.Biol., 15, 2008
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3WXB
 | | Crystal structure of NADPH bound carbonyl reductase from chicken fatty liver | | Descriptor: | 1,2-ETHANEDIOL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Uncharacterized protein | | Authors: | Yoneda, K, Sakuraba, H, Fukuda, Y, Sone, T, Araki, T, Ohshima, T. | | Deposit date: | 2014-07-29 | | Release date: | 2015-07-29 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure.
Febs J., 282, 2015
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3AUL
 | | Crystal structure of wild-type Lys48-linked diubiquitin in an open conformation | | Descriptor: | Polyubiquitin-C | | Authors: | Hirano, T, Olivier, S, Yagi, M, Takemoto, E, Hiromoto, T, Satoh, T, Mizushima, T, Kato, K. | | Deposit date: | 2011-02-09 | | Release date: | 2011-09-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.39 Å) | | Cite: | Conformational dynamics of wild-type Lys48-linked diubiquitin in solution
J.Biol.Chem., 286, 2011
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5B4N
 | | Structure analysis of function associated loop mutant of substrate recognition domain of Fbs1 ubiquitin ligase | | Descriptor: | F-box only protein 2 | | Authors: | Nishio, K, Yoshida, Y, Tanaka, K, Mizushima, T. | | Deposit date: | 2016-04-06 | | Release date: | 2016-09-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural analysis of a function-associated loop mutant of the substrate-recognition domain of Fbs1 ubiquitin ligase
Acta Crystallogr.,Sect.F, 72, 2016
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2ZJD
 | | Crystal Structure of LC3-p62 complex | | Descriptor: | Microtubule-associated proteins 1A/1B light chain 3B precursor, undecameric peptide from Sequestosome-1 | | Authors: | Ichimura, Y, Kumanomidou, T, Sou, Y, Mizushima, T, Ezaki, J, Ueno, T, Kominami, E, Yamane, T, Tanaka, K, Komatsu, M. | | Deposit date: | 2008-03-05 | | Release date: | 2008-06-03 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
J.Biol.Chem., 283, 2008
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5B0N
 | | Structure of Shigella effector LRR domain | | Descriptor: | E3 ubiquitin-protein ligase ipaH9.8 | | Authors: | Takagi, K, Sasakawa, C, Kim, M, Mizushima, T. | | Deposit date: | 2015-11-02 | | Release date: | 2016-04-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.8
Acta Crystallogr.,Sect.F, 72, 2016
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5B0T
 | | Structure of Shigella effector LRR domain | | Descriptor: | E3 ubiquitin-protein ligase ipaH9.8 | | Authors: | Takagi, K, Sasakawa, C, Kim, M, Mizushima, T. | | Deposit date: | 2015-11-04 | | Release date: | 2016-04-06 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the substrate-recognition domain of the Shigella E3 ligase IpaH9.8
Acta Crystallogr.,Sect.F, 72, 2016
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2H9V
 | | Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632 | | Descriptor: | (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, Rho-associated protein kinase 2 | | Authors: | Yamaguchi, H, Miwa, Y, Kasa, M, Kitano, K, Amano, M, Kaibuchi, K, Hakoshima, T. | | Deposit date: | 2006-06-12 | | Release date: | 2006-12-05 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632
J.Biochem.(Tokyo), 140, 2006
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3ANX
 | | Crystal structure of triamine/agmatine aminopropyltransferase (SPEE) from thermus thermophilus, complexed with MTA | | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, spermidine synthase | | Authors: | Ganbe, T, Ohnuma, M, Sato, T, Tanaka, N, Oshima, T, Kumasaka, T. | | Deposit date: | 2010-09-14 | | Release date: | 2011-04-13 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus
J.Mol.Biol., 408, 2011
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5B8C
 | | High resolution structure of the human PD-1 in complex with pembrolizumab Fv | | Descriptor: | Pembrolizumab heavy chain variable region (PemVH), Pembrolizumab light chain variable region (PemVL), Programmed cell death protein 1 | | Authors: | Horita, S, Shimamura, T, Iwata, S, Nomura, N. | | Deposit date: | 2016-06-14 | | Release date: | 2016-10-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.146 Å) | | Cite: | High-resolution crystal structure of the therapeutic antibody pembrolizumab bound to the human PD-1
Sci Rep, 6, 2016
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1VCV
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3WSO
 | | Crystal structure of the Skp1-FBG3 complex | | Descriptor: | F-box only protein 44, S-phase kinase-associated protein 1 | | Authors: | Kumanomidou, T, Nishio, K, Takagi, K, Nakagawa, T, Suzuki, A, Yamane, T, Tokunaga, F, Iwai, K, Murakami, A, Yoshida, Y, Tanaka, K, Mizushima, T. | | Deposit date: | 2014-03-18 | | Release date: | 2015-03-25 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Structural Differences between a Glycoprotein Specific F-Box Protein Fbs1 and Its Homologous Protein FBG3
Plos One, 10, 2015
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2JLN
 | | Structure of Mhp1, a nucleobase-cation-symport-1 family transporter | | Descriptor: | MERCURY (II) ION, MHP1, SODIUM ION | | Authors: | Weyand, S, Shimamura, T, Yajima, S, Suzuki, S, Mirza, O, Krusong, K, Carpenter, E.P, Rutherford, N.G, Hadden, J.M, O'Reilly, J, Ma, P, Saidijam, M, Patching, S.G, Hope, R.J, Norbertczak, H.T, Roach, P.C.J, Iwata, S, Henderson, P.J.F, Cameron, A.D. | | Deposit date: | 2008-09-11 | | Release date: | 2008-10-28 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure and Molecular Mechanism of a Nucleobase-Cation-Symport-1 Family Transporter.
Science, 322, 2008
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3VR0
 | | Crystal structure of Pyrococcus furiosus PbaB, an archaeal proteasome activator | | Descriptor: | GOLD ION, Putative uncharacterized protein | | Authors: | Kumoi, K, Satoh, T, Hiromoto, T, Mizushima, T, Kamiya, Y, Noda, M, Uchiyama, S, Murata, K, Yagi, H, Kato, K. | | Deposit date: | 2012-04-02 | | Release date: | 2013-04-03 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | An archaeal homolog of proteasome assembly factor functions as a proteasome activator
Plos One, 8, 2013
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3W21
 | | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase in complex with alpha-KG from Burkholderia ambifaria AMMD | | Descriptor: | 2-OXOGLUTARIC ACID, Putative uncharacterized protein, ZINC ION | | Authors: | Qin, H.M, Miyakawa, T, Jia, M.Z, Nakamura, A, Ohtsuka, J, Xue, Y.L, Kawashima, T, Kasahara, T, Hibi, M, Ogawa, J, Tanokura, M. | | Deposit date: | 2012-11-26 | | Release date: | 2013-07-17 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Crystal Structure of a Novel N-Substituted L-Amino Acid Dioxygenase from Burkholderia ambifaria AMMD
Plos One, 8, 2013
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