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9DC3
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BU of 9dc3 by Molmil
AAV8 in complex with the AAVX affinity ligand
Descriptor: AAVX affinity ligand, Capsid protein
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-08-25
Release date:2024-11-27
Last modified:2025-01-01
Method:ELECTRON MICROSCOPY (2.31 Å)
Cite:Structural characterization and epitope mapping of the AAVX affinity purification ligand.
Mol Ther Methods Clin Dev, 32, 2024
9B7T
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BU of 9b7t by Molmil
Fab3-3 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab3-3 heavy chain, Fab3-3 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-05-21
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6N
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BU of 9b6n by Molmil
Fab1-1 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-1 heavy chain, Fab1-1 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-09
Last modified:2025-06-25
Method:ELECTRON MICROSCOPY (3.31 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7V
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BU of 9b7v by Molmil
Fab3-5 in complex with the capsid of Adeno-associated virus type 9
Descriptor: CALCIUM ION, Capsid protein VP1, Fab3-5 heavy chain, ...
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7S
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BU of 9b7s by Molmil
Fab3-2 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab3-2 heavy chain, Fab3-2 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7U
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BU of 9b7u by Molmil
Fab3-4 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab3-4 heavy chain, Fab3-4 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7X
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BU of 9b7x by Molmil
Fab3-7 in complex with the capsid of Adeno-associated virus type 9
Descriptor: CALCIUM ION, Capsid protein VP1, Fab3-7 heavy chain, ...
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-05-28
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7R
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BU of 9b7r by Molmil
Fab3-1 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab3-1 heavy chain, Fab3-1 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-05-14
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7W
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BU of 9b7w by Molmil
Fab3-6 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab3-6 heavy chain, Fab3-6 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-02
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6O
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BU of 9b6o by Molmil
Fab1-2 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-2 heavy chain, Fab1-2 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (2.61 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6P
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BU of 9b6p by Molmil
Fab1-3 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-3 heavy chain, Fab1-3 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (3.13 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7L
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BU of 9b7l by Molmil
Fab2-2 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab2-2 heavy chain, Fab2-2 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7O
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BU of 9b7o by Molmil
Fab2-5 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab2-5 heavy chain, Fab2-5 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6T
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BU of 9b6t by Molmil
Fab1-7 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-7 heavy chain, Fab1-7 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (2.54 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7K
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BU of 9b7k by Molmil
Fab2-1 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab2-1 heavy chain, Fab2-1 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (2.75 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6S
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BU of 9b6s by Molmil
Fab1-6 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-6 heavy chain, Fab1-6 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B7N
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BU of 9b7n by Molmil
Fab2-4 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab2-4 heavy chain, Fab2-4 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-27
Release date:2025-04-16
Last modified:2025-06-04
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6R
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BU of 9b6r by Molmil
Fab1-5 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-5 heavy chain, Fab1-5 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9B6Q
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BU of 9b6q by Molmil
Fab1-4 in complex with the capsid of Adeno-associated virus type 9
Descriptor: Capsid protein VP1, Fab1-4 heavy chain, Fab1-4 light chain
Authors:Mietzsch, M, McKenna, R.
Deposit date:2024-03-25
Release date:2025-04-16
Last modified:2025-06-11
Method:ELECTRON MICROSCOPY (2.77 Å)
Cite:Structural characterization of antibody-responses following Zolgensma treatment for AAV capsid engineering to expand patient cohorts.
Nat Commun, 16, 2025
9CV9
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BU of 9cv9 by Molmil
Bufavirus 1 at pH 4.0
Descriptor: VP1
Authors:Gulkis, M.C, McKenna, R, Bennett, A.D.
Deposit date:2024-07-28
Release date:2024-08-28
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
9CV0
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BU of 9cv0 by Molmil
Bufavirus 1 at pH 7.4
Descriptor: VP1
Authors:Gulkis, M.C, McKenna, R, Bennett, A.D.
Deposit date:2024-07-27
Release date:2024-08-28
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.84 Å)
Cite:Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
9CWS
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BU of 9cws by Molmil
Bufavirus 1 at pH 2.6
Descriptor: VP1
Authors:Gulkis, M.C, McKenna, R, Bennett, A.D.
Deposit date:2024-07-30
Release date:2024-08-21
Last modified:2024-09-18
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
9CUZ
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BU of 9cuz by Molmil
Bufavirus 1 complexed with 6SLN
Descriptor: N-acetyl-alpha-neuraminic acid, VP1
Authors:Gulkis, M.C, McKenna, R, Bennett, A.D.
Deposit date:2024-07-27
Release date:2024-09-18
Method:ELECTRON MICROSCOPY (2.16 Å)
Cite:Structural Characterization of Human Bufavirus 1: Receptor Binding and Endosomal pH-Induced Changes.
Viruses, 16, 2024
6U4T
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BU of 6u4t by Molmil
Carbonic anhydrase 9 in complex with SB4197
Descriptor: 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION
Authors:Murray, A.B, Lomelino, C.L, McKenna, R.
Deposit date:2019-08-26
Release date:2020-01-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.356 Å)
Cite:"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
J.Med.Chem., 63, 2020
6UGQ
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BU of 6ugq by Molmil
Human Carbonic Anhydrase IX-mimic complexed with SB4-206
Descriptor: 5-chloro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase IX-mimic, ZINC ION
Authors:Murray, A.B, Lomelino, C.L, McKenna, R.
Deposit date:2019-09-26
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.305 Å)
Cite:"A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII.
J.Med.Chem., 63, 2020

238582

數據於2025-07-09公開中

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