9B6T

Fab1-7 in complex with the capsid of Adeno-associated virus type 9

Summary for 9B6T

Entry DOI	10.2210/pdb9b6t/pdb
EMDB information	44277
Descriptor	Capsid protein VP1, Fab1-7 heavy chain, Fab1-7 light chain (3 entities in total)
Functional Keywords	adeno-associated virus, aav, capsid, fab-complex, antibody, nab, virus, viral protein-immune system complex, viral protein/immune system
Biological source	Adeno-associated virus More
Total number of polymer chains	8
Total formula weight	383807.44
Authors	Mietzsch, M.,McKenna, R. (deposition date: 2024-03-25, release date: 2025-04-16)
Primary citation	Mietzsch, M.,Nelson, A.R.,Hsi, J.,Zachary, J.,Potts, L.,Chipman, P.,Ghanem, M.,Alexander, I.E.,Logan, G.J.,Huiskonen, J.,McKenna, R. Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing Nat Commun, 2025
Experimental method	ELECTRON MICROSCOPY (2.54 Å)

Structure validation