9B6N
Fab1-1 in complex with the capsid of Adeno-associated virus type 9
Summary for 9B6N
Entry DOI | 10.2210/pdb9b6n/pdb |
EMDB information | 44271 |
Descriptor | Capsid protein VP1, Fab1-1 heavy chain, Fab1-1 light chain (3 entities in total) |
Functional Keywords | adeno-associated virus, aav, capsid, fab-complex, antibody, nab, virus, viral protein-immune system complex, viral protein/immune system |
Biological source | Adeno-associated virus More |
Total number of polymer chains | 5 |
Total formula weight | 201332.07 |
Authors | Mietzsch, M.,McKenna, R. (deposition date: 2024-03-25, release date: 2025-04-09, Last modification date: 2025-05-21) |
Primary citation | Mietzsch, M.,Nelson, A.R.,Hsi, J.,Zachary, J.,Potts, L.,Chipman, P.,Ghanem, M.,Alexander, I.E.,Logan, G.J.,Huiskonen, J.,McKenna, R. Structural characterization of antibody-responses from Zolgensma treatment guides the design of a capsid suitable for redosing Nat Commun, 2025 |
Experimental method | ELECTRON MICROSCOPY (3.31 Å) |
Structure validation
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