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1HTI
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BU of 1hti by Molmil
CRYSTAL STRUCTURE OF RECOMBINANT HUMAN TRIOSEPHOSPHATE ISOMERASE AT 2.8 ANGSTROMS RESOLUTION. TRIOSEPHOSPHATE ISOMERASE RELATED HUMAN GENETIC DISORDERS AND COMPARISON WITH THE TRYPANOSOMAL ENZYME
Descriptor: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Mande, S.C, Hol, W.G.J.
Deposit date:1994-10-12
Release date:1995-01-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme.
Protein Sci., 3, 1994
1IIG
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BU of 1iig by Molmil
STRUCTURE OF TRYPANOSOMA BRUCEI BRUCEI TRIOSEPHOSPHATE ISOMERASE COMPLEXED WITH 3-PHOSPHONOPROPIONATE
Descriptor: 3-PHOSPHONOPROPANOIC ACID, TRIOSEPHOSPHATE ISOMERASE
Authors:Noble, M.E, Wierenga, R.K, Lambeir, A.M, Opperdoes, F.R, Thunnissen, A.M, Kalk, K.H, Groendijk, H, Hol, W.G.J.
Deposit date:2001-04-23
Release date:2001-05-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The adaptability of the active site of trypanosomal triosephosphate isomerase as observed in the crystal structures of three different complexes.
Proteins, 10, 1991
4GFT
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BU of 4gft by Molmil
Malaria invasion machinery protein-Nanobody complex
Descriptor: 1,2-ETHANEDIOL, Myosin A tail domain interacting protein, Nanobody
Authors:Khamrui, S, Turley, S, Pardon, E, Steyaert, J, Verlinde, C, Fan, E, Bergman, L.W, Hol, W.G.J.
Deposit date:2012-08-03
Release date:2013-07-03
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
4JTM
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BU of 4jtm by Molmil
Structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli
Descriptor: Type II secretion system protein D
Authors:Korotkov, K.V, Delarosa, J.R, Hol, W.G.J.
Deposit date:2013-03-23
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:A dodecameric ring-like structure of the N0 domain of the type II secretin from enterotoxigenic Escherichia coli.
J.Struct.Biol., 18, 2013
4IDL
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BU of 4idl by Molmil
Low melting temperature Anti-Cholera Toxin Llama VHH domain
Descriptor: Single Domain Antibody VHH A9
Authors:Legler, P.M, Lam, A, Hol, W.G.J.
Deposit date:2012-12-12
Release date:2013-02-13
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Structure of a low-melting-temperature anti-cholera toxin: llama V(H)H domain.
Acta Crystallogr.,Sect.F, 69, 2013
1BI2
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BU of 1bi2 by Molmil
STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor: DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E, Hol, W.G.J.
Deposit date:1998-06-21
Release date:1999-06-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
1BI3
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BU of 1bi3 by Molmil
STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor: DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION
Authors:Pohl, E, Hol, W.G.J.
Deposit date:1998-06-21
Release date:1999-06-22
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
1BI1
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BU of 1bi1 by Molmil
STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR
Descriptor: DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E, Hol, W.G.J.
Deposit date:1998-06-21
Release date:1999-06-22
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR.
J.Biol.Chem., 273, 1998
4J75
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BU of 4j75 by Molmil
Crystal Structure of a parasite tRNA synthetase, product-bound
Descriptor: GLYCEROL, TRYPTOPHANYL-5'AMP, Tryptophanyl-tRNA synthetase
Authors:Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:2013-02-12
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
4J76
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BU of 4j76 by Molmil
Crystal Structure of a parasite tRNA synthetase, ligand-free
Descriptor: GLYCEROL, Tryptophanyl-tRNA synthetase
Authors:Koh, C.Y, Kim, J.E, Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:2013-02-12
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Crystal structures of Plasmodium falciparum cytosolic tryptophanyl-tRNA synthetase and its potential as a target for structure-guided drug design.
Mol.Biochem.Parasitol., 189, 2013
4GGN
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BU of 4ggn by Molmil
Malaria invasion machinery protein complex
Descriptor: Myosin A tail domain interacting protein MTIP, Myosin-A
Authors:Khamrui, S, Turley, S, Bergman, L.W, Hol, W.G.J.
Deposit date:2012-08-06
Release date:2013-07-03
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:The structure of the D3 domain of Plasmodium falciparum myosin tail interacting protein MTIP in complex with a nanobody.
Mol.Biochem.Parasitol., 190, 2013
1F8W
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BU of 1f8w by Molmil
CRYSTAL STRUCTURE OF NADH PEROXIDASE MUTANT: R303M
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH PEROXIDASE
Authors:Yeh, J.I, Claiborne, A, Hol, W.G.J.
Deposit date:2000-07-05
Release date:2001-02-05
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Analysis of the kinetic and redox properties of the NADH peroxidase R303M mutant: correlation with the crystal structure.
Biochemistry, 39, 2000
2BTM
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BU of 2btm by Molmil
DOES THE HIS12-LYS13 PAIR PLAY A ROLE IN THE ADAPTATION OF THERMOPHILIC TIMS TO HIGH TEMPERATURES?
Descriptor: 2-PHOSPHOGLYCOLIC ACID, PROTEIN (TRIOSEPHOSPHATE ISOMERASE)
Authors:Delboni, L.F, Mande, S.C, Hol, W.G.J.
Deposit date:1999-01-04
Release date:1999-01-13
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Lys13 plays a crucial role in the functional adaptation of the thermophilic triose-phosphate isomerase from Bacillus stearothermophilus to high temperatures.
J.Biol.Chem., 274, 1999
1LT4
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BU of 1lt4 by Molmil
HEAT-LABILE ENTEROTOXIN MUTANT S63K
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1997-04-14
Release date:1997-06-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a non-toxic mutant of heat-labile enterotoxin, which is a potent mucosal adjuvant.
Protein Sci., 6, 1997
1YF9
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BU of 1yf9 by Molmil
Structural analysis of Leishmania major ubiquitin conjugating enzyme E2
Descriptor: CHLORIDE ION, Ubiquitin carrier protein 4
Authors:Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-12-31
Release date:2005-02-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Analysis of Leishmania major ubiquitin conjugating enzyme E2
To be Published
1A7K
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BU of 1a7k by Molmil
GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN A MONOCLINIC CRYSTAL FORM
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION
Authors:Kim, H, Hol, W.G.J.
Deposit date:1998-03-16
Release date:1998-06-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of Leishmania mexicana glycosomal glyceraldehyde-3-phosphate dehydrogenase in a new crystal form confirms the putative physiological active site structure.
J.Mol.Biol., 278, 1998
2BSX
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BU of 2bsx by Molmil
Crystal structure of the Plasmodium falciparum purine nucleoside phosphorylase complexed with inosine
Descriptor: INOSINE, PURINE NUCLEOSIDE PHOSPHORYLASE
Authors:Schnick, C, Brzozowski, A.M, Dodson, E.J, Murshudov, G.N, Brannigan, J.A, Wilkinson, A.J.
Deposit date:2005-05-24
Release date:2005-08-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Plasmodium Falciparum Purine Nucleoside Phosphorylase Complexed with Sulfate and its Natural Substrate Inosine
Acta Crystallogr.,Sect.D, 61, 2005
1QS0
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BU of 1qs0 by Molmil
Crystal Structure of Pseudomonas Putida 2-oxoisovalerate Dehydrogenase (Branched-Chain Alpha-Keto Acid Dehydrogenase, E1B)
Descriptor: 2-OXO-4-METHYLPENTANOIC ACID, 2-OXOISOVALERATE DEHYDROGENASE ALPHA-SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA-SUBUNIT, ...
Authors:Aevarsson, A, Seger, K, Turley, S, Sokatch, J.R, Hol, W.G.J.
Deposit date:1999-06-24
Release date:1999-08-18
Last modified:2021-08-04
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes.
Nat.Struct.Biol., 6, 1999
1NHS
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BU of 1nhs by Molmil
AN L40C MUTATION CONVERTS THE CYSTEINE-SULFENIC ACID REDOX CENTRE IN ENTEROCOCCAL NADH PEROXIDASE TO A DISULFIDE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH PEROXIDASE, SULFATE ION
Authors:Mande, S.S, Claiborne, A, Hol, W.G.J.
Deposit date:1994-12-09
Release date:1995-02-14
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:An L40C mutation converts the cysteine-sulfenic acid redox center in enterococcal NADH peroxidase to a disulfide.
Biochemistry, 34, 1995
1NHR
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BU of 1nhr by Molmil
AN L40C MUTATION CONVERTS THE CYSTEINE-SULFENIC ACID REDOX CENTRE IN ENTEROCOCCAL NADH PEROXIDASE TO A DISULFIDE
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, NADH PEROXIDASE, SULFATE ION
Authors:Mande, S.S, Claiborne, A, Hol, W.G.J.
Deposit date:1994-12-09
Release date:1995-02-14
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An L40C mutation converts the cysteine-sulfenic acid redox center in enterococcal NADH peroxidase to a disulfide.
Biochemistry, 34, 1995
1LT3
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BU of 1lt3 by Molmil
HEAT-LABILE ENTEROTOXIN DOUBLE MUTANT N40C/G166C
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
Authors:Van Den Akker, F, Hol, W.G.J.
Deposit date:1997-04-12
Release date:1997-07-07
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of heat-labile enterotoxin from Escherichia coli with increased thermostability introduced by an engineered disulfide bond in the A subunit.
Protein Sci., 6, 1997
1LT5
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BU of 1lt5 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH THIODIGALACTOSIDE
Descriptor: HEAT-LABILE ENTEROTOXIN, beta-D-galactopyranose-(1-1)-1-thio-beta-D-galactopyranose
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1997-09-30
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Structure, 5, 1997
1LT6
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BU of 1lt6 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER COMPLEXED WITH METANITROPHENYLGALACTOSIDE
Descriptor: 3-nitrophenyl alpha-D-galactopyranoside, HEAT-LABILE ENTEROTOXIN
Authors:Merritt, E.A, Hol, W.G.J.
Deposit date:1997-10-01
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural foundation for the design of receptor antagonists targeting Escherichia coli heat-labile enterotoxin.
Structure, 5, 1997
4DFR
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BU of 4dfr by Molmil
CRYSTAL STRUCTURES OF ESCHERICHIA COLI AND LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE REFINED AT 1.7 ANGSTROMS RESOLUTION. I. GENERAL FEATURES AND BINDING OF METHOTREXATE
Descriptor: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ...
Authors:Filman, D.J, Matthews, D.A, Bolin, J.T, Kraut, J.
Deposit date:1982-06-25
Release date:1982-10-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
J.Biol.Chem., 257, 1982
1AG1
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BU of 1ag1 by Molmil
MONOHYDROGEN PHOSPHATE BINDING TO TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE
Descriptor: PHOSPHATE ION, TRIOSEPHOSPHATE ISOMERASE
Authors:Verlinde, C.L.M.J, Hol, W.G.J.
Deposit date:1997-03-28
Release date:1997-06-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Anion binding at the active site of trypanosomal triosephosphate isomerase. Monohydrogen phosphate does not mimic sulphate.
Eur.J.Biochem., 198, 1991

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