7ZSB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zsb by Molmil](/molmil-images/mine/7zsb) | |
7ZSA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zsa by Molmil](/molmil-images/mine/7zsa) | |
7ZS9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7zs9 by Molmil](/molmil-images/mine/7zs9) | |
1NMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1nmk by Molmil](/molmil-images/mine/1nmk) | The Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data | Descriptor: | (13E,15E)-(3S,6S,9R,10R,11S,12S,18S,21S)-10,12-DIHYDROXY-3-(3-HYDROXYBEN-ZYL)-18-((E)-3-HYDROXY-1-METHYLPROPENYL)-6-ISOPROPYL-11-METHYL-9-(3-OXO-BUTYL)-19-OXA-1,4,7,25-TETRAAZA-BICYCLO[19.3.1]PENTACOSA-13,15-DIENE-2,5,8,20-TETRAONE, Peptidyl-prolyl cis-trans isomerase A | Authors: | Kallen, J, Sedrani, R, Wagner, J. | Deposit date: | 2003-01-10 | Release date: | 2003-04-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Sanglifehrin-Cyclophilin Interaction: Degradation Work, Synthetic Macrocyclic Analogues, X-ray Crystal Structure and Binding Data J.Am.Chem.Soc., 125, 2003
|
|
6AZW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6azw by Molmil](/molmil-images/mine/6azw) | IDO1/FXB-001116 crystal structure | Descriptor: | (2R)-N-(4-cyanophenyl)-2-[cis-4-(quinolin-4-yl)cyclohexyl]propanamide, Indoleamine 2,3-dioxygenase 1 | Authors: | Lewis, H.A, Lammens, A, Steinbacher, S. | Deposit date: | 2017-09-13 | Release date: | 2018-03-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
7M2G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m2g by Molmil](/molmil-images/mine/7m2g) | INTERLEUKIN-2 (human) mutant P65K, C125S | Descriptor: | GLYCEROL, Interleukin-2, SULFATE ION | Authors: | Ptacin, J.L, Milla, M.E, Steinbacher, S, Maskos, K, Thomsen, M. | Deposit date: | 2021-03-16 | Release date: | 2021-08-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | An engineered IL-2 reprogrammed for anti-tumor therapy using a semi-synthetic organism. Nat Commun, 12, 2021
|
|
1B33
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1b33 by Molmil](/molmil-images/mine/1b33) | STRUCTURE OF LIGHT HARVESTING COMPLEX OF ALLOPHYCOCYANIN ALPHA AND BETA CHAINS/CORE-LINKER COMPLEX AP*LC7.8 | Descriptor: | ALLOPHYCOCYANIN, ALPHA CHAIN, BETA CHAIN, ... | Authors: | Reuter, W, Wiegand, G, Huber, R, Than, M.E. | Deposit date: | 1998-12-15 | Release date: | 1999-02-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis at 2.2 A of orthorhombic crystals presents the asymmetry of the allophycocyanin-linker complex, AP.LC7.8, from phycobilisomes of Mastigocladus laminosus. Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
1E0R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1e0r by Molmil](/molmil-images/mine/1e0r) | Beta-apical domain of thermosome | Descriptor: | THERMOSOME | Authors: | Bosch, G, Baumeister, W, Essen, L.-O. | Deposit date: | 2000-04-06 | Release date: | 2000-08-19 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Beta-Apical Domain from Thermosome Reveals Structural Plasticity in Protrusion Region J.Mol.Biol., 301, 2000
|
|
2VFO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vfo by Molmil](/molmil-images/mine/2vfo) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V125L | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
|
|
2VFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vfq by Molmil](/molmil-images/mine/2vfq) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V450A | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN,, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
|
|
2VFN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vfn by Molmil](/molmil-images/mine/2vfn) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V125A | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, GLYCEROL, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
|
|
2XU1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2xu1 by Molmil](/molmil-images/mine/2xu1) | CATHEPSIN L WITH A NITRILE INHIBITOR | Descriptor: | (2S,4R)-1-[1-(4-chlorophenyl)cyclopropyl]carbonyl-4-(2-chlorophenyl)sulfonyl-N-[1-(iminomethyl)cyclopropyl]pyrrolidine-2-carboxamide, CATHEPSIN L1 | Authors: | Banner, D.W, Benz, J.M, Steinbacher, S, Haap, W. | Deposit date: | 2010-10-14 | Release date: | 2011-01-12 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Systematic Investigation of Halogen Bonding in Protein-Ligand Interactions. Angew.Chem.Int.Ed.Engl., 50, 2011
|
|
2VFM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vfm by Molmil](/molmil-images/mine/2vfm) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666) | Descriptor: | BIFUNCTIONAL TAIL PROTEIN, CALCIUM ION, GLYCEROL, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
|
|
2VFP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2vfp by Molmil](/molmil-images/mine/2vfp) | Low Temperature Structure of P22 Tailspike Protein Fragment (109-666), Mutant V349L | Descriptor: | CALCIUM ION, GLYCEROL, P22 TAILSPIKE PROTEIN, ... | Authors: | Becker, M, Mueller, J.J, Heinemann, U, Seckler, R. | Deposit date: | 2007-11-05 | Release date: | 2008-12-16 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Side-Chain Stacking and Beta-Helix Stability in P22 Tailspike Protein To be Published
|
|
4L3P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l3p by Molmil](/molmil-images/mine/4l3p) | Crystal Structure of 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine bound to TAK1-TAB1 | Descriptor: | 2-(1-benzothiophen-7-yl)-4-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]furo[2,3-c]pyridin-7-amine, Mitogen-activated protein kinase kinase kinase 7, TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera | Authors: | Wang, J, Hornberger, K.R, Crew, A.P, Steinbacher, S, Maskos, K, Moertl, M. | Deposit date: | 2013-06-06 | Release date: | 2013-06-19 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Discovery and optimization of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1. Bioorg.Med.Chem.Lett., 23, 2013
|
|
1YND
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ynd by Molmil](/molmil-images/mine/1ynd) | Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6A resolution | Descriptor: | Peptidyl-prolyl cis-trans isomerase A, SANGLIFEHRIN A | Authors: | Kallen, J, Sedrani, R, Zenke, G, Wagner, J. | Deposit date: | 2005-01-24 | Release date: | 2005-04-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6 A resolution. J.Biol.Chem., 280, 2005
|
|