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3FOC
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BU of 3foc by Molmil
Tryptophanyl-tRNA synthetase from Giardia lamblia
Descriptor: GLYCEROL, SULFATE ION, Tryptophanyl-tRNA synthetase
Authors:Arakaki, T.L, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
Deposit date:2008-12-29
Release date:2009-01-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:The structure of tryptophanyl-tRNA synthetase from Giardia lamblia reveals divergence from eukaryotic homologs.
J.Struct.Biol., 171, 2010
1DTW
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BU of 1dtw by Molmil
HUMAN BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE
Descriptor: BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE ALPHA SUBUNIT, BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE BETA SUBUNIT, MAGNESIUM ION, ...
Authors:AEvarsson, A, Chuang, J.L, Wynn, R.M, Turley, S, Chuang, D.T, Hol, W.G.J.
Deposit date:2000-01-13
Release date:2000-03-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease.
Structure Fold.Des., 8, 2000
1EPX
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BU of 1epx by Molmil
CRYSTAL STRUCTURE ANALYSIS OF ALDOLASE FROM L. MEXICANA
Descriptor: FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE
Authors:Chudzik, D.M, Michels, P.A, de Walque, S, Hol, W.G.J.
Deposit date:2000-03-29
Release date:2000-07-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases.
J.Mol.Biol., 300, 2000
1EBD
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BU of 1ebd by Molmil
DIHYDROLIPOAMIDE DEHYDROGENASE COMPLEXED WITH THE BINDING DOMAIN OF THE DIHYDROLIPOAMIDE ACETYLASE
Descriptor: DIHYDROLIPOAMIDE ACETYLTRANSFERASE, DIHYDROLIPOAMIDE DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Mande, S.S, Sarfaty, S, Allen, M.D, Perham, R.N, Hol, W.G.J.
Deposit date:1996-02-03
Release date:1996-07-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Protein-protein interactions in the pyruvate dehydrogenase multienzyme complex: dihydrolipoamide dehydrogenase complexed with the binding domain of dihydrolipoamide acetyltransferase.
Structure, 4, 1996
1EYE
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BU of 1eye by Molmil
1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE
Descriptor: DIHYDROPTEROATE SYNTHASE I, MAGNESIUM ION, PTERIN-6-YL-METHYL-MONOPHOSPHATE
Authors:Baca, A.M, Sirawaraporn, R, Turley, S, Sirawaraporn, W, Hol, W.G.J.
Deposit date:2000-05-05
Release date:2000-10-11
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
J.Mol.Biol., 302, 2000
1EVZ
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BU of 1evz by Molmil
CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH NAD
Descriptor: GLYCEROL-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PENTADECANE
Authors:Suresh, S, Turley, S, Opperdoes, F.R, Michels, P.A.M, Hol, W.G.J.
Deposit date:2000-04-21
Release date:2001-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
Structure Fold.Des., 8, 2000
1EVY
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BU of 1evy by Molmil
CRYSTAL STRUCTURE OF LEISHMANIA MEXICANA GLYCEROL-3-PHOSPHATE DEHYDROGENASE
Descriptor: GLYCEROL-3-PHOSPHATE DEHYDROGENASE, PENTADECANE
Authors:Suresh, S, Turley, S, Opperdoes, F.R, Michels, P.A.M, Hol, W.G.J.
Deposit date:2000-04-20
Release date:2001-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana.
Structure Fold.Des., 8, 2000
1F2J
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BU of 1f2j by Molmil
CRYSTAL STRUCTURE ANALYSIS OF ALDOLASE FROM T. BRUCEI
Descriptor: FRUCTOSE-BISPHOSPHATE ALDOLASE, GLYCOSOMAL
Authors:Chudzik, D.M, Michels, P.A, De Walque, S, Hol, W.G.J.
Deposit date:2000-05-25
Release date:2000-07-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases.
J.Mol.Biol., 300, 2000
1FD7
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BU of 1fd7 by Molmil
HEAT-LABILE ENTEROTOXIN B-PENTAMER WITH BOUND LIGAND BMSC001
Descriptor: HEAT-LABILE ENTEROTOXIN B CHAIN, N-BENZYL-3-(ALPHA-D-GALACTOS-1-YL)-BENZAMIDE
Authors:Fan, E, Merritt, E.A, Pickens, J, Ahn, M, Hol, W.G.J.
Deposit date:2000-07-19
Release date:2000-08-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Exploration of the GM1 receptor-binding site of heat-labile enterotoxin and cholera toxin by phenyl-ring-containing galactose derivatives.
Acta Crystallogr.,Sect.D, 57, 2001
1FM2
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BU of 1fm2 by Molmil
THE 2 ANGSTROM CRYSTAL STRUCTURE OF CEPHALOSPORIN ACYLASE
Descriptor: GLUTARYL 7-AMINOCEPHALOSPORANIC ACID ACYLASE
Authors:Kim, Y, Yoon, K.H, Khang, Y, Turley, S, Hol, W.G.J.
Deposit date:2000-08-15
Release date:2001-08-15
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0 A crystal structure of cephalosporin acylase.
Structure Fold.Des., 8, 2000
1G3S
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BU of 1g3s by Molmil
CYS102SER DTXR
Descriptor: DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3Y
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BU of 1g3y by Molmil
ARG80ALA DTXR
Descriptor: DIPHTHERIA TOXIN REPRESSOR, ZINC ION
Authors:Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1FX7
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BU of 1fx7 by Molmil
CRYSTAL STRUCTURE OF THE IRON-DEPENDENT REGULATOR (IDER) FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor: COBALT (II) ION, IRON-DEPENDENT REPRESSOR IDER, SULFATE ION
Authors:Feese, M.D, Ingason, B.P, Goranson-Siekierke, J, Holmes, R.K, Hol, W.J.G.
Deposit date:2000-09-25
Release date:2001-03-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the iron-dependent regulator from Mycobacterium tuberculosis at 2.0-A resolution reveals the Src homology domain 3-like fold and metal binding function of the third domain.
J.Biol.Chem., 276, 2001
1FWZ
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BU of 1fwz by Molmil
GLU20ALA DTXR
Descriptor: DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION
Authors:Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
Deposit date:2000-09-25
Release date:2001-09-25
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3T
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BU of 1g3t by Molmil
CYS102SER DTXR
Descriptor: DIPHTHERIA TOXIN REPRESSOR
Authors:Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1G3W
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BU of 1g3w by Molmil
CD-CYS102SER DTXR
Descriptor: CADMIUM ION, DIPHTHERIA TOXIN REPRESSOR, SULFATE ION
Authors:Pohl, E, Goranson-Siekierke, J, Holmes, R.K, Hol, W.G.J.
Deposit date:2000-10-25
Release date:2001-10-25
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of three diphtheria toxin repressor (DtxR) variants with decreased repressor activity.
Acta Crystallogr.,Sect.D, 57, 2001
1GYQ
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BU of 1gyq by Molmil
CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE FROM LEISHMANIA MEXICANA IN COMPLEX WITH N6-BENZYL-NAD
Descriptor: N6-BENZYL-NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE)
Authors:Suresh, S, Hol, W.
Deposit date:1999-03-05
Release date:1999-03-16
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.
Proc.Natl.Acad.Sci.USA, 96, 1999
1X9G
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BU of 1x9g by Molmil
PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA DONOVANI
Descriptor: PUTATIVE MAR1
Authors:Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-08-20
Release date:2004-09-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
1XN4
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BU of 1xn4 by Molmil
PUTATIVE MAR1 RIBONUCLEASE FROM LEISHMANIA MAJOR
Descriptor: ribonuclease MAR1
Authors:Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2004-10-04
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
1GYP
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BU of 1gyp by Molmil
CRYSTAL STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM LEISHMANIA MEXICANA: IMPLICATIONS FOR STRUCTURE-BASED DRUG DESIGN AND A NEW POSITION FOR THE INORGANIC PHOSPHATE BINDING SITE
Descriptor: GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION
Authors:Kim, H, Feil, I.K, Verlinde, C.L.M.J, Petra, P.H, Hol, W.G.J.
Deposit date:1995-08-01
Release date:1995-12-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Leishmania mexicana: implications for structure-based drug design and a new position for the inorganic phosphate binding site.
Biochemistry, 34, 1995
1HXI
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BU of 1hxi by Molmil
AN UNEXPECTED EXTENDED CONFORMATION FOR THE THIRD TPR MOTIF OF THE PEROXIN PEX5 FROM TRYPANOSOMA BRUCEI
Descriptor: MAGNESIUM ION, PEROXISOME TARGETING SIGNAL 1 RECEPTOR PEX5
Authors:Kumar, A, Roach, C, Hirsh, I.S, Turley, S, deWalque, S, Michels, P.A.M, Hol, W.G.J.
Deposit date:2001-01-15
Release date:2001-03-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:An unexpected extended conformation for the third TPR motif of the peroxin PEX5 from Trypanosoma brucei.
J.Mol.Biol., 307, 2001
1I33
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BU of 1i33 by Molmil
LEISHMANIA MEXICANA GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE IN COMPLEX WITH INHIBITORS
Descriptor: GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE, N-1,2,3,4-TETRAHYDRONAPHTH-1-YL-2'-[3,5-DIMETHOXYBENZAMIDO]-2'-DEOXY-ADENOSINE
Authors:Suresh, S, Bressi, J.C, Kennedy, K.J, Verlinde, C.L.M.J, Gelb, M.H, Hol, W.G.J.
Deposit date:2001-02-12
Release date:2001-10-03
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors.
J.Mol.Biol., 309, 2001
1YZV
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BU of 1yzv by Molmil
HYPOTHETICAL PROTEIN FROM TRYPANOSOMA CRUZI
Descriptor: HYPOTHETICAL PROTEIN, SULFATE ION
Authors:Caruthers, J, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-02-28
Release date:2005-03-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily.
Protein Sci., 14, 2005
1ZSO
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BU of 1zso by Molmil
Hypothetical protein from plasmodium falciparum
Descriptor: hypothetical protein
Authors:Holmes, M.A, Merritt, E.A, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
Deposit date:2005-05-24
Release date:2005-06-07
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.
Acta Crystallogr.,Sect.F, 62, 2006
1OXY
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BU of 1oxy by Molmil
CRYSTALLOGRAPHIC ANALYSIS OF OXYGENATED AND DEOXYGENATED STATES OF ARTHROPOD HEMOCYANIN SHOWS UNUSUAL DIFFERENCES
Descriptor: COPPER (II) ION, HEMOCYANIN (SUBUNIT TYPE II), OXYGEN MOLECULE
Authors:Ton-that, H, Magnus, K.
Deposit date:1995-01-06
Release date:1995-02-27
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences.
Proteins, 19, 1994

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