4TNE
| Crystal Structure of Human Transthyretin Thr119Tyr Mutant | Descriptor: | GLYCEROL, Transthyretin | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-06-03 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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6PWS
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6PWT
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4TLS
| Crystal Structure of Human Transthyretin Glu92Pro Mutant | Descriptor: | GLYCEROL, PHOSPHATE ION, SODIUM ION, ... | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TLT
| Crystal structure of human transthyretin | Descriptor: | MAGNESIUM ION, Transthyretin | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TLK
| Crystal Structure of Human Transthyretin Ser85Pro/Glu92Pro Mutant | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SODIUM ION, ... | Authors: | Saelices, L, Cascio, D, Sawaya, M, Eisenberg, D.S. | Deposit date: | 2014-05-30 | Release date: | 2015-10-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Uncovering the Mechanism of Aggregation of Human Transthyretin. J.Biol.Chem., 290, 2015
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4TM9
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4RIK
| Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77 | Descriptor: | Alpha-synuclein | Authors: | Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S. | Deposit date: | 2014-10-06 | Release date: | 2015-08-26 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.854 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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4TJX
| Crystal structure of protease-associated domain of Arabidopsis VSR1 in complex with aleurain peptide | Descriptor: | Aleurain peptide, Vacuolar-sorting receptor 1 | Authors: | Luo, F, Fong, Y.H, Jiang, L.W, Wong, K.B. | Deposit date: | 2014-05-25 | Release date: | 2014-12-10 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.902 Å) | Cite: | How vacuolar sorting receptor proteins interact with their cargo proteins: crystal structures of apo and cargo-bound forms of the protease-associated domain from an Arabidopsis vacuolar sorting receptor. Plant Cell, 26, 2014
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8ITR
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4TJV
| Crystal structure of protease-associated domain of Arabidopsis vacuolar sorting receptor 1 | Descriptor: | IODIDE ION, Vacuolar-sorting receptor 1 | Authors: | Luo, F, Fong, Y.H, Jiang, L.W, Wong, K.B. | Deposit date: | 2014-05-25 | Release date: | 2014-12-10 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | How vacuolar sorting receptor proteins interact with their cargo proteins: crystal structures of apo and cargo-bound forms of the protease-associated domain from an Arabidopsis vacuolar sorting receptor. Plant Cell, 26, 2014
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6T3L
| PAS-GAF fragment from Deinococcus radiodurans phytochrome in dark state | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | Authors: | Claesson, E, Takala, H, Yuan Wahlgren, W, Pandey, S, Schmidt, M, Westenhoff, S. | Deposit date: | 2019-10-11 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser. Elife, 9, 2020
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6T3U
| PAS-GAF fragment from Deinococcus radiodurans phytochrome 1ps after photoexcitation | Descriptor: | 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(4-ethenyl-3-methyl-5-oxidanylidene-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-1-ium -2-ylidene]methyl]-5-[(Z)-[(3E)-3-ethylidene-4-methyl-5-oxidanylidene-pyrrolidin-2-ylidene]methyl]-4-methyl-1H-pyrrol-3- yl]propanoic acid, Bacteriophytochrome | Authors: | Claesson, E, Takala, H, Yuan Wahlgren, W, Pandey, S, Schmidt, M, Westenhoff, S. | Deposit date: | 2019-10-11 | Release date: | 2020-04-08 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | The primary structural photoresponse of phytochrome proteins captured by a femtosecond X-ray laser. Elife, 9, 2020
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6N6B
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6ITE
| Crystal structure of group A Streptococcal surface dehydrogenase (SDH) | Descriptor: | Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION | Authors: | Yuan, C, Li, R, Huang, M.D. | Deposit date: | 2018-11-21 | Release date: | 2019-09-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.739 Å) | Cite: | Structural determination of group A Streptococcal surface dehydrogenase and characterization of its interaction with urokinase-type plasminogen activator receptor. Biochem.Biophys.Res.Commun., 510, 2019
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6XVD
| Crystal structure of complex of urokinase and a upain-1 variant(W3F) in pH7.4 condition | Descriptor: | Urokinase-type plasminogen activator, upain-1-W3F | Authors: | Xue, G.P, Xie, X, Zhou, Y, Yuan, C, Huang, M.D, Jiang, L.G. | Deposit date: | 2020-01-21 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Insight to the residue in P2 position prevents the peptide inhibitor from being hydrolyzed by serine proteases. Biosci.Biotechnol.Biochem., 84, 2020
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4XFO
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4XFN
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5DUP
| Influenza A virus H5 hemagglutinin globular head in complex with antibody AVFluIgG03 | Descriptor: | AVFluIgG03 Heavy Chain, AVFluIgG03 Light Chain, Hemagglutinin | Authors: | Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L. | Deposit date: | 2015-09-20 | Release date: | 2015-12-16 | Method: | X-RAY DIFFRACTION (3.052 Å) | Cite: | Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
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5DUT
| Influenza A virus H5 hemagglutinin globular head | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | Authors: | Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L. | Deposit date: | 2015-09-20 | Release date: | 2015-12-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
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5DUM
| Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody 65C6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 65C6 Heavy Chain, 65C6 Light Chain, ... | Authors: | Sun, J, Zuo, T, Wang, G, Zhou, P, Zhang, L, Wang, X. | Deposit date: | 2015-09-19 | Release date: | 2015-12-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.003 Å) | Cite: | Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
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5DUR
| Influenza A virus H5 hemagglutinin globular head in complex with antibody 100F4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy Chain of Antibody 100F4, Hemagglutinin, ... | Authors: | Zuo, T, Sun, J, Wang, G, Zhou, P, Wang, X, Zhang, L. | Deposit date: | 2015-09-20 | Release date: | 2015-12-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.82 Å) | Cite: | Comprehensive analysis of antibody recognition in convalescent humans from highly pathogenic avian influenza H5N1 infection Nat Commun, 6, 2015
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8TBF
| Tricomplex of RMC-7977, KRAS WT, and CypA | Descriptor: | (1R,5S,6r)-N-[(1P,7S,9S,13S,20M)-20-{5-(4-cyclopropylpiperazin-1-yl)-2-[(1S)-1-methoxyethyl]pyridin-3-yl}-21-ethyl-17,17-dimethyl-8,14-dioxo-15-oxa-4-thia-9,21,27,28-tetraazapentacyclo[17.5.2.1~2,5~.1~9,13~.0~22,26~]octacosa-1(24),2,5(28),19,22,25-hexaen-7-yl]-3-oxabicyclo[3.1.0]hexane-6-carboxamide, 1,2-ETHANEDIOL, GTPase KRas, ... | Authors: | Tomlinson, A.C.A, Chen, A, Knox, J.E, Yano, J.K. | Deposit date: | 2023-06-28 | Release date: | 2024-02-07 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Concurrent inhibition of oncogenic and wild-type RAS-GTP for cancer therapy. Nature, 629, 2024
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4ZS6
| Receptor binding domain and Fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein, fab Heavy Chain, ... | Authors: | Yu, X, Wang, X. | Deposit date: | 2015-05-13 | Release date: | 2015-09-02 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.166 Å) | Cite: | Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27 Sci Rep, 5, 2015
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5JKG
| The crystal structure of FGFR4 kinase domain in complex with LY2874455 | Descriptor: | 2-[4-[E-2-[5-[(1R)-1-[3,5-bis(chloranyl)pyridin-4-yl]ethoxy]-1H-indazol-3-yl]ethenyl]pyrazol-1-yl]ethanol, Fibroblast growth factor receptor 4 | Authors: | Wu, D, Chen, L, Chen, Y. | Deposit date: | 2016-04-26 | Release date: | 2016-10-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.352 Å) | Cite: | Crystal Structure of the FGFR4/LY2874455 Complex Reveals Insights into the Pan-FGFR Selectivity of LY2874455 Plos One, 11, 2016
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