3OEI
| Crystal structure of Mycobacterium tuberculosis RelJK (Rv3357-Rv3358-RelBE3) | Descriptor: | CITRATE ANION, RelJ (Antitoxin Rv3357), RelK (Toxin Rv3358) | Authors: | Miallau, L, Cascio, D, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2010-08-12 | Release date: | 2011-03-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.145 Å) | Cite: | Comparative proteomics identifies the cell-associated lethality of M. tuberculosis RelBE-like toxin-antitoxin complexes. Structure, 21, 2013
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3L2X
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4RIL
| Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction | Descriptor: | Alpha-synuclein | Authors: | Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S. | Deposit date: | 2014-10-06 | Release date: | 2015-08-26 | Last modified: | 2023-09-20 | Method: | ELECTRON CRYSTALLOGRAPHY (1.43 Å) | Cite: | Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525, 2015
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4RO5
| Crystal structure of the SAT domain from the non-reducing fungal polyketide synthase CazM | Descriptor: | GLYCEROL, SAT domain from CazM | Authors: | Winter, J.M, Cascio, D, Sawaya, M.R, Tang, Y. | Deposit date: | 2014-10-27 | Release date: | 2015-09-09 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. J.Am.Chem.Soc., 137, 2015
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4RPM
| Crystal structure of the SAT domain from the non-reducing fungal polyketide synthase CazM with bound hexanoyl | Descriptor: | HEXANOIC ACID, HEXANOYL-COENZYME A, SAT domain from CazM | Authors: | Winter, J.M, Cascio, D, Sawaya, M.R, Tang, Y. | Deposit date: | 2014-10-30 | Release date: | 2015-09-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Biochemical and Structural Basis for Controlling Chemical Modularity in Fungal Polyketide Biosynthesis. J.Am.Chem.Soc., 137, 2015
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3EMN
| The Crystal Structure of Mouse VDAC1 at 2.3 A resolution | Descriptor: | 1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE, Voltage-dependent anion-selective channel protein 1 | Authors: | Ujwal, R, Cascio, D, Colletier, J.-P, Faham, S, Zhang, J, Toro, L, Ping, P, Abramson, J. | Deposit date: | 2008-09-24 | Release date: | 2008-12-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating Proc.Natl.Acad.Sci.USA, 105, 2008
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4RUB
| A CRYSTAL FORM OF RIBULOSE-1,5-BISPHOSPHATE CARBOXYLASE(SLASH)OXYGENASE FROM NICOTIANA TABACUM IN THE ACTIVATED STATE | Descriptor: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, FORMIC ACID, MAGNESIUM ION, ... | Authors: | Schreuder, H, Cascio, D, Curmi, P.M.G, Eisenberg, D. | Deposit date: | 1990-05-25 | Release date: | 1992-10-15 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A crystal form of ribulose-1,5-bisphosphate carboxylase/oxygenase from Nicotiana tabacum in the activated state. J.Mol.Biol., 197, 1987
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3DH4
| Crystal Structure of Sodium/Sugar symporter with bound Galactose from vibrio parahaemolyticus | Descriptor: | ERBIUM (III) ION, SODIUM ION, Sodium/glucose cotransporter, ... | Authors: | Abramson, J, Faham, S, Cascio, D. | Deposit date: | 2008-06-16 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of a sodium galactose transporter reveals mechanistic insights into Na+/sugar symport. Science, 321, 2008
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3IV5
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3JR9
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3JRF
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3JRD
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3JRG
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3JRE
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3JRA
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3SGP
| Amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | Authors: | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2011-06-15 | Release date: | 2012-03-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4016 Å) | Cite: | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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3JRB
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3JRH
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4RZT
| Lac repressor engineered to bind sucralose, sucralose-bound tetramer | Descriptor: | 4-chloro-4-deoxy-alpha-D-galactopyranose-(1-2)-1,6-dichloro-1,6-dideoxy-beta-D-fructofuranose, Lac repressor | Authors: | Arbing, M.A, Cascio, D, Sawaya, M.R, Kosuri, S, Church, G.M. | Deposit date: | 2014-12-24 | Release date: | 2015-12-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13, 2016
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4RZS
| Lac repressor engineered to bind sucralose, unliganded tetramer | Descriptor: | GLYCEROL, Lac repressor | Authors: | Arbing, M.A, Cascio, D, Kosuri, S, Church, G.M. | Deposit date: | 2014-12-24 | Release date: | 2015-12-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Engineering an allosteric transcription factor to respond to new ligands. Nat.Methods, 13, 2016
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3JTC
| Importance of Mg2+ in the Ca2+-Dependent Folding of the gamma-Carboxyglutamic Acid Domains of Vitamin K-Dependent clotting and anticlotting Proteins | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Endothelial protein C receptor, ... | Authors: | Bajaj, S.P, Vadivel, K, Agah, S, Cascio, D, Krishnaswamy, S, Esmon, C, Padmanabhan, K. | Deposit date: | 2009-09-11 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural and Functional Studies of gamma-Carboxyglutamic Acid Domains of Factor VIIa and Activated Protein C: Role of Magnesium at Physiological Calcium. J.Mol.Biol., 425, 2013
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3JRC
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3JRI
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3SGN
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3SGM
| Bromoderivative-2 of amyloid-related segment of alphaB-crystallin residues 90-100 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha-crystallin B chain | Authors: | Laganowsky, A, Sawaya, M.R, Cascio, D, Eisenberg, D. | Deposit date: | 2011-06-15 | Release date: | 2012-03-21 | Method: | X-RAY DIFFRACTION (1.7006 Å) | Cite: | Atomic view of a toxic amyloid small oligomer. Science, 335, 2012
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