8GJU
| Crystal structure of human methylmalonyl-CoA mutase (MMUT) in complex with methylmalonic acidemia type A protein (MMAA), coenzyme A, and GDP | Descriptor: | COENZYME A, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Mascarenhas, R.M, Ruetz, M, Gouda, H, Yaw, M, Banerjee, R. | Deposit date: | 2023-03-16 | Release date: | 2023-08-09 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.79 Å) | Cite: | Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair. Nat Commun, 14, 2023
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6X8Z
| Crystal structure of N-truncated human B12 chaperone CblD(C262S)-thiolato-cob(III)alamin complex (108-296) | Descriptor: | COBALAMIN, Methylmalonic aciduria and homocystinuria type D protein, mitochondrial | Authors: | Mascarenhas, R, Li, Z, Koutmos, M, Banerjee, R. | Deposit date: | 2020-06-02 | Release date: | 2020-09-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | An Interprotein Co-S Coordination Complex in the B 12 -Trafficking Pathway. J.Am.Chem.Soc., 142, 2020
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8DYJ
| Crystal structure of human methylmalonyl-CoA mutase in complex with ADP and cob(II)alamin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, COBALAMIN, Methylmalonyl-CoA mutase, ... | Authors: | Mascarenhas, R.N, Gouda, H, Banerjee, R. | Deposit date: | 2022-08-04 | Release date: | 2023-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair. Proc.Natl.Acad.Sci.USA, 120, 2023
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8DYL
| Crystal structure of human methylmalonyl-CoA mutase bound to aquocobalamin | Descriptor: | COBALAMIN, GLYCEROL, Methylmalonyl-CoA mutase, ... | Authors: | Mascarenhas, R.N, Gouda, H, Banerjee, R. | Deposit date: | 2022-08-04 | Release date: | 2023-07-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair. Proc.Natl.Acad.Sci.USA, 120, 2023
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