4HMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hmk by Molmil](/molmil-images/mine/4hmk) | Crystal structure of LeuT-E290S with bound Br | Descriptor: | BROMIDE ION, LEUCINE, SODIUM ION, ... | Authors: | Kantcheva, A.K, Quick, M, Shi, L, Winther, A.M.L, Stolzenberg, S, Weinstein, H, Javitch, J.A, Nissen, P. | Deposit date: | 2012-10-18 | Release date: | 2013-05-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The chloride binding site of Neurotransmitter Sodium Symporters Proc.Natl.Acad.Sci.USA, 2013
|
|
4HOD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4hod by Molmil](/molmil-images/mine/4hod) | Crystal structure of LeuT-E290S with bound Cl | Descriptor: | CHLORIDE ION, LEUCINE, SODIUM ION, ... | Authors: | Kantcheva, A.K, Quick, M, Shi, L, Winther, A.M.L, Stolzenberg, S, Weinstein, H, Javitch, J.A, Nissen, P. | Deposit date: | 2012-10-22 | Release date: | 2013-05-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | The chloride binding site of Neurotransmitter Sodium Symporters Proc.Natl.Acad.Sci.USA, 2013
|
|
6OY3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6oy3 by Molmil](/molmil-images/mine/6oy3) | nhTMEM16 L302A +Ca2+ in nanodiscs | Descriptor: | CALCIUM ION, nhTMEM16 | Authors: | Falzone, M, Lee, B.C, Accardi, A. | Deposit date: | 2019-05-14 | Release date: | 2019-11-06 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Dynamic modulation of the lipid translocation groove generates a conductive ion channel in Ca 2+ -bound nhTMEM16. Nat Commun, 10, 2019
|
|
6XWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xwm by Molmil](/molmil-images/mine/6xwm) | Mechanism of substrate release in neurotransmitter:sodium symporters: the structure of LeuT in an inward-facing occluded conformation | Descriptor: | Na(+):neurotransmitter symporter (Snf family), PHENYLALANINE, SODIUM ION | Authors: | Boesen, T, Nissen, P, Gotfryd, K, Loland, C.J, Gether, U. | Deposit date: | 2020-01-24 | Release date: | 2020-05-06 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | X-ray structure of LeuT in an inward-facing occluded conformation reveals mechanism of substrate release. Nat Commun, 11, 2020
|
|
4X2S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4x2s by Molmil](/molmil-images/mine/4x2s) | |
3GJD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjd by Molmil](/molmil-images/mine/3gjd) | Crystal Structure of LeuT with bound OG | Descriptor: | CHLORIDE ION, LEUCINE, SODIUM ION, ... | Authors: | Winther, A.M.L, Quick, M, Javitch, J.A, Nissen, P. | Deposit date: | 2009-03-08 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
3GJC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3gjc by Molmil](/molmil-images/mine/3gjc) | Crystal Structure of the E290S mutant of LeuT with bound OG | Descriptor: | LEUCINE, SODIUM ION, Transporter, ... | Authors: | Winther, A.M.L, Quick, M, Javitch, J.A, Nissen, P. | Deposit date: | 2009-03-08 | Release date: | 2009-04-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Binding of an octylglucoside detergent molecule in the second substrate (S2) site of LeuT establishes an inhibitor-bound conformation Proc.Natl.Acad.Sci.USA, 106, 2009
|
|
6UWL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uwl by Molmil](/molmil-images/mine/6uwl) | |
6UWF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6uwf by Molmil](/molmil-images/mine/6uwf) | GltPh in complex with L-aspartate and sodium ions in outward-facing state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate | Authors: | Wang, X, Boudker, O. | Deposit date: | 2019-11-05 | Release date: | 2020-06-03 | Last modified: | 2020-11-18 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Use of paramagnetic 19 F NMR to monitor domain movement in a glutamate transporter homolog. Nat.Chem.Biol., 16, 2020
|
|