4PIR
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![BU of 4pir by Molmil](/molmil-images/mine/4pir) | X-ray structure of the mouse serotonin 5-HT3 receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5-hydroxytryptamine receptor 3A, ... | Authors: | Hassaine, G, Deluz, C, Grasso, L, Wyss, R, Tol, M.B, Hovius, R, Graff, A, Stahlberg, H, Tomizaki, T, Desmyter, A, Moreau, C, Li, X.-D, Poitevin, F, Vogel, H, Nury, H. | Deposit date: | 2014-05-09 | Release date: | 2014-08-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | X-ray structure of the mouse serotonin 5-HT3 receptor. Nature, 512, 2014
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6Y59
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![BU of 6y59 by Molmil](/molmil-images/mine/6y59) | 5-HT3A receptor in Salipro (apo, C5 symmetric) | Descriptor: | 5-hydroxytryptamine receptor 3A | Authors: | Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M. | Deposit date: | 2020-02-25 | Release date: | 2020-12-23 | Last modified: | 2021-03-03 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers. Nat Commun, 12, 2021
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6Y5A
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![BU of 6y5a by Molmil](/molmil-images/mine/6y5a) | Serotonin-bound 5-HT3A receptor in Salipro | Descriptor: | 5-hydroxytryptamine receptor 3A, SEROTONIN | Authors: | Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M. | Deposit date: | 2020-02-25 | Release date: | 2020-12-23 | Last modified: | 2021-03-03 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers. Nat Commun, 12, 2021
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6Y5B
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![BU of 6y5b by Molmil](/molmil-images/mine/6y5b) | 5-HT3A receptor in Salipro (apo, asymmetric) | Descriptor: | 5-hydroxytryptamine receptor 3A | Authors: | Zhang, Y, Dijkman, P.M, Zou, R, Zandl-Lang, M, Sanchez, R.M, Eckhardt-Strelau, L, Koefeler, H, Vogel, H, Yuan, S, Kudryashev, M. | Deposit date: | 2020-02-25 | Release date: | 2020-12-23 | Last modified: | 2021-03-03 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Asymmetric opening of the homopentameric 5-HT 3A serotonin receptor in lipid bilayers. Nat Commun, 12, 2021
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2MQE
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![BU of 2mqe by Molmil](/molmil-images/mine/2mqe) | |
5IWL
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![BU of 5iwl by Molmil](/molmil-images/mine/5iwl) | CD47-diabody complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5F9 diabody, Leukocyte surface antigen CD47, ... | Authors: | Di, W, Jude, K.M, Garcia, K.C. | Deposit date: | 2016-03-22 | Release date: | 2016-06-29 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | CD47-blocking immunotherapies stimulate macrophage-mediated destruction of small-cell lung cancer. J.Clin.Invest., 126, 2016
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8GQU
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![BU of 8gqu by Molmil](/molmil-images/mine/8gqu) | AK-42 inhibitor binding human ClC-2 TMD | Descriptor: | 2-[[2,6-bis(chloranyl)-3-phenylmethoxy-phenyl]amino]pyridine-3-carboxylic acid, Chloride channel protein 2 | Authors: | Wang, L. | Deposit date: | 2022-08-30 | Release date: | 2023-07-05 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42. Nat Commun, 14, 2023
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2L1W
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7XLB
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![BU of 7xlb by Molmil](/molmil-images/mine/7xlb) | |
7XJA
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![BU of 7xja by Molmil](/molmil-images/mine/7xja) | TMD masked refine map of human ClC-2 | Descriptor: | Chloride channel protein 2 | Authors: | Wang, L. | Deposit date: | 2022-04-15 | Release date: | 2023-05-17 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14, 2023
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7XF5
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![BU of 7xf5 by Molmil](/molmil-images/mine/7xf5) | Full length human CLC-2 channel in apo state | Descriptor: | Chloride channel protein 2 | Authors: | Wang, L. | Deposit date: | 2022-04-01 | Release date: | 2023-05-03 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Cryo-EM structures of ClC-2 chloride channel reveal the blocking mechanism of its specific inhibitor AK-42 Nat Commun, 14, 2023
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8C1W
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![BU of 8c1w by Molmil](/molmil-images/mine/8c1w) | |
8C21
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![BU of 8c21 by Molmil](/molmil-images/mine/8c21) | |
8C20
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![BU of 8c20 by Molmil](/molmil-images/mine/8c20) | |
8C1Z
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![BU of 8c1z by Molmil](/molmil-images/mine/8c1z) | |
4HIQ
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![BU of 4hiq by Molmil](/molmil-images/mine/4hiq) | The Structure of V122I Mutant Transthyretin in Complex with AG10 | Descriptor: | 3-[3-(3,5-dimethyl-1H-pyrazol-4-yl)propoxy]-4-fluorobenzoic acid, Transthyretin | Authors: | Connelly, S, Alhamadsheh, M, Graef, I, Wilson, I.A. | Deposit date: | 2012-10-11 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.18 Å) | Cite: | AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. Proc.Natl.Acad.Sci.USA, 110, 2013
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4HIS
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![BU of 4his by Molmil](/molmil-images/mine/4his) | The Structure of V122I Mutant Transthyretin in Complex with Tafamidis | Descriptor: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | Authors: | Connelly, S, Alhamadsheh, M, Graef, I, Wilson, I.A. | Deposit date: | 2012-10-11 | Release date: | 2013-06-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin. Proc.Natl.Acad.Sci.USA, 110, 2013
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