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7Z5L
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BU of 7z5l by Molmil
Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and dimethyl sulfoxide (DMSO)
Descriptor: GLYCEROL, Insulin A chain, Insulin B chain, ...
Authors:van den Elsen, J.M.H, Wahid, A.A, Crennell, C.
Deposit date:2022-03-09
Release date:2023-03-22
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
7Z5Q
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BU of 7z5q by Molmil
Crystal structure of human insulin, crystallised in the presence of macrophage migration inhibitory factor (MIF) and p-Hydroxyphenylpyruvate (HPP)
Descriptor: Insulin, Insulin A chain, SULFATE ION
Authors:van den Elsen, J.M.H, Wahid, A.A, Crennell, S.J.
Deposit date:2022-03-09
Release date:2023-03-22
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dissociation of Hexameric Insulin Facilitated by Macrophage Migration Inhibitory Factor Indicates a Novel Role in Insulin Signalling
To Be Published
6RMT
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BU of 6rmt by Molmil
Crystal structure of disulphide-linked human C3d dimer
Descriptor: CHLORIDE ION, Complement C3
Authors:Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J.
Deposit date:2019-05-07
Release date:2020-11-18
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insights Into the Structure-Function Relationships of Dimeric C3d Fragments.
Front Immunol, 12, 2021
6RMU
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BU of 6rmu by Molmil
Crystal structure of disulphide-linked human C3d dimer in complex with Staphylococcus aureus complement subversion protein Sbi-IV
Descriptor: 1,2-ETHANEDIOL, Complement C3, DI(HYDROXYETHYL)ETHER, ...
Authors:Wahid, A.A, van den Elsen, J.M.H, Crennell, S.J.
Deposit date:2019-05-07
Release date:2020-11-18
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Staphylococcal Complement Evasion Protein Sbi Stabilises C3d Dimers by Inducing an N-Terminal Helix Swap
Front Immunol, 13, 2022
1MPA
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BU of 1mpa by Molmil
BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
Descriptor: CADMIUM ION, MN12H2 IGG2A-KAPPA, PORA P1.16 PEPTIDE FLUORESCEIN CONJUGATE
Authors:Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
Deposit date:1997-02-26
Release date:1997-09-04
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
2MPA
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BU of 2mpa by Molmil
BACTERICIDAL ANTIBODY AGAINST NEISSERIA MENINGITIDIS
Descriptor: CADMIUM ION, CONJUGATE OF PORA P1.16 PEPTIDE WITH FLUORESCEIN, MN12H2 IGG2A-KAPPA, ...
Authors:Van Den Elsen, J.M.H, Herron, J.N, Kroon, J, Gros, P.
Deposit date:1999-06-09
Release date:1999-06-23
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Bactericidal antibody recognition of a PorA epitope of Neisseria meningitidis: crystal structure of a Fab fragment in complex with a fluorescein-conjugated peptide.
Proteins, 29, 1997
1HTY
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BU of 1hty by Molmil
GOLGI ALPHA-MANNOSIDASE II
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R.
Deposit date:2001-01-02
Release date:2002-01-02
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
1HXK
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BU of 1hxk by Molmil
GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH DEOXYMANNOJIRIMICIN
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1-DEOXYMANNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R.
Deposit date:2001-01-16
Release date:2002-01-16
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
1HWW
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BU of 1hww by Molmil
GOLGI ALPHA-MANNOSIDASE II IN COMPLEX WITH SWAINSONINE
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 1S-8AB-OCTAHYDRO-INDOLIZIDINE-1A,2A,8B-TRIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:van den Elsen, J.M.H, Kuntz, D.A, Rose, D.R.
Deposit date:2001-01-10
Release date:2002-01-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of Golgi alpha-mannosidase II: a target for inhibition of growth and metastasis of cancer cells.
EMBO J., 20, 2001
1HZF
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BU of 1hzf by Molmil
C4ADG FRAGMENT OF HUMAN COMPLEMENT FACTOR C4A
Descriptor: COMPLEMENT FACTOR C4A
Authors:van den Elsen, J.M.H, Martin, A, Wong, V, Clemenza, L, Rose, D.R, Isenman, D.E.
Deposit date:2001-01-24
Release date:2002-10-09
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystal structure of the C4d fragment of human complement component C4.
J.Mol.Biol., 322, 2002
2AP2
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BU of 2ap2 by Molmil
SINGLE CHAIN FV OF C219 IN COMPLEX WITH SYNTHETIC EPITOPE PEPTIDE
Descriptor: P-GLYCOPROTEIN, SINGLE CHAIN FV
Authors:Van Den Elsen, J.M.H, Rose, D.R.
Deposit date:1999-03-22
Release date:1999-11-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein.
Proc.Natl.Acad.Sci.USA, 96, 1999
4OFS
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BU of 4ofs by Molmil
Crystal structure of a truncated catalytic core of the 2-oxoacid dehydrogenase multienzyme complex from Thermoplasma acidophilum
Descriptor: Probable lipoamide acyltransferase
Authors:Marrot, N.L, Marshall, J.J.T, Svergun, D.I, Crennell, S.J, Hough, D.W, van den Elsen, J.M.H, Danson, M.J.
Deposit date:2014-01-15
Release date:2014-12-10
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.
Biochem.J., 463, 2014
7AD6
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BU of 7ad6 by Molmil
Crystal structure of human complement C5 in complex with the K92 bovine knob domain peptide.
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CYSTEINE, ...
Authors:Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R.
Deposit date:2020-09-14
Release date:2021-03-10
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
7AD7
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BU of 7ad7 by Molmil
Crystal structure of human complement C5 in complex with the K8 bovine knob domain peptide.
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Macpherson, A, van den Elsen, J.M.H, Schulze, M.E, Birtley, J.R.
Deposit date:2020-09-14
Release date:2021-03-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The allosteric modulation of Complement C5 by knob domain peptides.
Elife, 10, 2021
3OED
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BU of 3oed by Molmil
The structure of the complex between complement receptor CR2 and its ligand complement fragment C3d
Descriptor: Complement C3, Complement receptor type 2
Authors:Isenman, D.E, van den Elsen, J.M.H.
Deposit date:2010-08-12
Release date:2011-05-11
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:A crystal structure of the complex between human complement receptor 2 and its ligand C3d.
Science, 332, 2011
1QUB
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BU of 1qub by Molmil
CRYSTAL STRUCTURE OF THE GLYCOSYLATED FIVE-DOMAIN HUMAN BETA2-GLYCOPROTEIN I PURIFIED FROM BLOOD PLASMA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (human beta2-Glycoprotein I), ...
Authors:Bouma, B, de Groot, P.G, van den Elsen, J.M.H, Ravelli, R.B.G, Schouten, A, Simmelink, M.J.A, Derksen, R.H.W.M, Kroon, J, Gros, P.
Deposit date:1999-07-01
Release date:1999-10-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.
EMBO J., 18, 1999
2JVG
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BU of 2jvg by Molmil
Structure of C3-binding domain 4 of Staphylococcus aureus protein Sbi
Descriptor: IgG-binding protein SBI
Authors:Upadhyay, A, Burman, J, Clark, E.A, van den Elsen, J.M.H, Bagby, S.
Deposit date:2007-09-20
Release date:2008-06-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi.
J.Biol.Chem., 283, 2008
2JVH
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BU of 2jvh by Molmil
Structure of C3-binding domain 4 of S. aureus protein Sbi
Descriptor: IgG-binding protein SBI
Authors:Upadhyay, A, Burman, J, Clark, E.A, van den Elsen, J.M.H, Bagby, S.
Deposit date:2007-09-20
Release date:2008-06-10
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi.
J.Biol.Chem., 283, 2008
2JOL
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BU of 2jol by Molmil
Average NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei
Descriptor: Putative G-nucleotide exchange factor
Authors:Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S.
Deposit date:2007-03-14
Release date:2007-03-27
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Biochem.J., 411, 2008
2JOK
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BU of 2jok by Molmil
NMR structure of the catalytic domain of guanine nucleotide exchange factor BopE from Burkholderia pseudomallei
Descriptor: Putative G-nucleotide exchange factor
Authors:Wu, H, Upadhyay, A, Williams, C, Galyov, E.E, van den Elsen, J.M.H, Bagby, S.
Deposit date:2007-03-14
Release date:2007-09-18
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:The guanine-nucleotide-exchange factor BopE from Burkholderia pseudomallei adopts a compact version of the Salmonella SopE/SopE2 fold and undergoes a closed-to-open conformational change upon interaction with Cdc42
Biochem.J., 411, 2008
3RQC
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BU of 3rqc by Molmil
Crystal structure of the catalytic core of the 2-oxoacid dehydrogenase multienzyme complex from Thermoplasma acidophilum
Descriptor: Probable lipoamide acyltransferase
Authors:Marrott, N.L, Crennell, S.J, Hough, D.W, Danson, M.J, van den Elsen, J.M.H.
Deposit date:2011-04-28
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.01 Å)
Cite:The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly.
Febs J., 279, 2012

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数据于2024-11-13公开中

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